Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease

(2019) Silvia C Bobeica et al.   eLife

Biosynthesis and Chemical Applications of Thioamides

(2019) Nilkamal Mahanta et al.   ACS Chemical Biology

Biosynthesis of Diverse Antimicrobial and Antiproliferative Acyloins in Anaerobic Bacteria

(2019) Sebastian Schieferdecker et al.   ACS Chemical Biology

Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals a Novel Nonribosomal Peptide Backbone-Tailoring Strategy

(2019) Kyle L. Dunbar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Thioamide Formation in Bacterial Antimetabolite Pathway

(2018) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ironing out siderophore biosynthesis: a review of non-ribosomal peptide synthetase (NRPS)-independent siderophore synthetases

(2018) Cassandra S. Carroll et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria

(2018) Kyle Dunbar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

‘Democratized’ genomic enzymology web tools for functional assignment

(2018) Rémi Zallot et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Natural products from anaerobes

(2018) Jeffrey S. Li et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database

(2017) Neil D Rawlings et al.   NUCLEIC ACIDS RESEARCH

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks

(2015) John A. Gerlt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs

(2015) Fumitaka Kudo et al.   CHEMICAL RECORD

Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors

(2015) Alina Iulia Chiriac et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome

(2015) Anwesha Goswami et al.   Molecular BioSystems

The tRNA-Dependent Biosynthesis of Modified Cyclic Dipeptides

(2014) Tobias Giessen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Formation of a Dinuclear Copper(I) Complex from theClostridium-Derived Antibiotic Closthioamide

(2013) Florian Kloss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life

(2013) Joris Beld et al.   NATURAL PRODUCT REPORTS

Antiterminator-Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium

(2012) Swantje Behnken et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The ATP-grasp enzymes

(2011) Maria V. Fawaz et al.   BIOORGANIC CHEMISTRY

Highly Efficient Total Synthesis of the Clostridium-Derived anti-MRSA Antibiotic Closthioamide

(2011) Florian Kloss et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Closthioamide: An Unprecedented Polythioamide Antibiotic from the Strictly Anaerobic Bacterium Clostridium cellulolyticum

(2010) Thorger Lincke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase

(2009) Andrew M. Gulick   ACS Chemical Biology

Biosynthetic genes for aminoglycoside antibiotics

(2009) Fumitaka Kudo et al.   JOURNAL OF ANTIBIOTICS