Contact-ID, a tool for profiling organelle contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation

Directed Evolution of Split APEX2 Peroxidase

(2019) Yisu Han et al.   ACS Chemical Biology

Atlas of Subcellular RNA Localization Revealed by APEX-Seq

(2019) Furqan M. Fazal et al.   CELL

How large B-factors can be in protein crystal structures

(2018) Oliviero Carugo   BMC BIOINFORMATICS

Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

(2018) Emily Tubbs et al.   DIABETES

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

(2018) Tomofumi Misaka et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics

(2018) Justyna Janikiewicz et al.   Cell Death & Disease

Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages

(2018) Edgar Djaha Yoboue et al.   Cell Death & Disease

Wolfram syndrome: MAMs’ connection?

(2018) Benjamin Delprat et al.   Cell Death & Disease

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75

(2018) Manuela D’Eletto et al.   Cell Reports

Split-BioID: a proximity biotinylation assay for dimerization-dependent protein interactions

(2017) Sofie De Munter et al.   FEBS LETTERS

Introducing inducible fluorescent split cholesterol oxidase to mammalian cells

(2017) Konstantin G. Chernov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ascorbate peroxidase proximity labeling coupled with biochemical fractionation identifies promoters of endoplasmic reticulum–mitochondrial contacts

(2017) Il-Taeg Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Architecture Mapping of the Inner Mitochondrial Membrane Proteome by Chemical Tools in Live Cells

(2017) Song-Yi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Architecture of the human interactome defines protein communities and disease networks

(2017) Edward L. Huttlin et al.   NATURE

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases

(2017) Pierre Theurey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Identification of microsporidia host-exposed proteins reveals a repertoire of rapidly evolving proteins

(2017) Aaron W. Reinke et al.   Nature Communications

Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes

(2017) Isabel Myriam Schopp et al.   Nature Communications

Mitochondria chaperone GRP75 moonlighting as a cell cycle controller to derail endocytosis provides an opportunity for nanomicrosphere intracellular delivery

(2017) Zhihui Gao et al.   Oncotarget

DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca 2+ Transfer through the MAM

(2017) Sung Jin Park et al.   Cell Reports

Comparative Proteomic Analysis of the Mitochondria-associated ER Membrane (MAM) in a Long-term Type 2 Diabetic Rodent Model

(2017) Jacey Hongjie Ma et al.   Scientific Reports

Optimizing the fragment complementation of APEX2 for detection of specific protein-protein interactions in live cells

(2017) Miaomiao Xue et al.   Scientific Reports

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts

(2016) Ken H. Loh et al.   CELL

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria-associated ER membranes and Alzheimer disease

(2016) Estela Area-Gomez et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Emerging Network of Mitochondria-Organelle Contacts

(2016) Andrew Murley et al.   MOLECULAR CELL

A split horseradish peroxidase for the detection of intercellular protein–protein interactions and sensitive visualization of synapses

(2016) Jeffrey D Martell et al.   NATURE BIOTECHNOLOGY

Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization

(2016) Heather L. Glasgow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver

(2016) Pierre Theurey et al.   Journal of Molecular Cell Biology

Versatile protein tagging in cells with split fluorescent protein

(2016) Daichi Kamiyama et al.   Nature Communications

Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells

(2016) Song-Yi Lee et al.   ACS Central Science

Structure and function of ER membrane contact sites with other organelles

(2015) Melissa J. Phillips et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteomic Analysis of Mitochondrial-Associated ER Membranes (MAM) during RNA Virus Infection Reveals Dynamic Changes in Protein and Organelle Trafficking

(2015) Stacy M. Horner et al.   PLoS One

New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

(2014) Xue-Wen Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway

(2014) Shotaro Saita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

(2014) Ana Paula Arruda et al.   NATURE MEDICINE

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

(2014) Junji Suzuki et al.   Nature Communications

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)

(2013) Chloe N. Poston et al.   Journal of Proteomics

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Lipid Transport between the Endoplasmic Reticulum and Mitochondria

(2013) V. V. Flis et al.   Cold Spring Harbor Perspectives in Biology

Selective escape of proteins from the mitochondria during mitophagy

(2013) Shotaro Saita et al.   Nature Communications

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

(2012) Malena B. Rone et al.   MOLECULAR ENDOCRINOLOGY

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

(2012) Jeffrey D Martell et al.   NATURE BIOTECHNOLOGY

Calcium signaling around Mitochondria Associated Membranes (MAMs)

(2011) Simone Patergnani et al.   Cell Communication and Signaling

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

mGRASP enables mapping mammalian synaptic connectivity with light microscopy

(2011) Jinhyun Kim et al.   NATURE METHODS

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

(2011) Marian L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Staying in touch: the molecular era of organelle contact sites

(2011) Yael Elbaz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oxidative protein folding in the endoplasmic reticulum: Tight links to the mitochondria-associated membrane (MAM)

(2010) Thomas Simmen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM)

(2010) Susanna Y. Gilady et al.   CELL STRESS & CHAPERONES

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

Detergent-Resistant Microdomains Determine the Localization of  -1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction

(2010) T. Hayashi et al.   MOLECULAR PHARMACOLOGY

Organelle-specific, rapid induction of molecular activities and membrane tethering

(2010) Toru Komatsu et al.   NATURE METHODS

Ca2+ transfer from the ER to mitochondria: When, how and why

(2009) Rosario Rizzuto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1

(2009) Natasha C Chang et al.   EMBO JOURNAL

Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

(2009) Sandra Barth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols