mCSM-membrane: predicting the effects of mutations on transmembrane proteins

Structure guided prediction of Pyrazinamide resistance mutations in pncA

(2020) Malancha Karmakar et al.   Scientific Reports

Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU

(2019) David B. Ascher et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Empirical ways to identify novel Bedaquiline resistance mutations in AtpE

(2019) Malancha Karmakar et al.   PLoS One

Prediction of disease-associated mutations in the transmembrane regions of proteins with known 3D structure

(2019) Petr Popov et al.   PLoS One

Variant type is associated with disease characteristics in SDHB, SDHC and SDHD-linked phaeochromocytoma–paraganglioma

(2019) Jean Pierre Bayley et al.   JOURNAL OF MEDICAL GENETICS

Analysis of a Novel pncA Mutation for Susceptibility to Pyrazinamide Therapy

(2018) Malancha Karmakar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genesSDHB,SDHCandSDHD

(2018) Katrina A Andrews et al.   JOURNAL OF MEDICAL GENETICS

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation

(2018) Aleš Hnízda et al.   LEUKEMIA

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

(2018) Kathryn E. Holt et al.   NATURE GENETICS

Kinact: a computational approach for predicting activating missense mutations in protein kinases

(2018) Carlos HM Rodrigues et al.   NUCLEIC ACIDS RESEARCH

Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae

(2018) Sundeep Chaitanya Vedithi et al.   Scientific Reports

Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis

(2018) Stephanie Portelli et al.   Scientific Reports

Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design

(2017) Amanda T.S. Albanaz et al.   Expert Opinion on Drug Discovery

Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures

(2017) Harry C Jubb et al.   JOURNAL OF MOLECULAR BIOLOGY

mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions

(2017) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

Familial STAG2 germline mutation defines a new human cohesinopathy

(2017) Fernanda C. Soardi et al.   npj Genomic Medicine

SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity

(2017) Ruth T. Casey et al.   Molecular Genetics & Genomic Medicine

Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability

(2016) Brett M. Kroncke et al.   BIOCHEMISTRY

Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance

(2016) Jody Phelan et al.   BMC Medicine

Tumour risks and genotype–phenotype–proteotype analysis of patients with germline mutations in the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD

(2016) Katrina A Andrews et al.   LANCET

mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures

(2016) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

CSM-lig: a web server for assessing and comparing protein–small molecule affinities

(2016) Douglas E.V. Pires et al.   NUCLEIC ACIDS RESEARCH

Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses

(2016) Ana Carolina Rios Silvino et al.   PLoS One

mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance

(2016) Douglas E. V. Pires et al.   Scientific Reports

The Presence, Persistence and Functional Properties of Plasmodium vivax Duffy Binding Protein II Antibodies Are Influenced by HLA Class II Allelic Variants

(2016) Flora S. Kano et al.   PLoS Neglected Tropical Diseases

Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis

(2016) Rhiannon R. White et al.   PLoS Pathogens

Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy

(2015) Martina Nemethova et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma

(2015) M. Jafri et al.   Cancer Discovery

Genetic Variations and Diseases in UniProtKB/Swiss-Prot: The Ins and Outs of Expert Manual Curation

(2014) Maria Livia Famiglietti et al.   HUMAN MUTATION

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach

(2014) D. E. V. Pires et al.   NUCLEIC ACIDS RESEARCH

Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins

(2013) Joseph J Babcock et al.   ACTA PHARMACOLOGICA SINICA

Protter: interactive protein feature visualization and integration with experimental proteomic data

(2013) Ulrich Omasits et al.   BIOINFORMATICS

ModBase, a database of annotated comparative protein structure models and associated resources

(2013) Ursula Pieper et al.   NUCLEIC ACIDS RESEARCH

Prediction of the human membrane proteome

(2010) Linn Fagerberg et al.   PROTEOMICS

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS