Fluid Brain Glycolysis: Limits, Speed, Location, Moonlighting, and the Fates of Glycogen and Lactate

Aerobic Glycolysis in the Brain: Warburg and Crabtree Contra Pasteur

(2020) L. Felipe Barros et al.   NEUROCHEMICAL RESEARCH

The Science and Translation of Lactate Shuttle Theory

(2018) George A. Brooks   Cell Metabolism

Lactate metabolism: historical context, prior misinterpretations, and current understanding

(2018) Brian S. Ferguson et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

CrossTalk opposing view: lack of evidence supporting an astrocyte-to-neuron lactate shuttle coupling neuronal activity to glucose utilisation in the brain

(2018) Lasse K. Bak et al.   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk proposal: an important astrocyte-to-neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain

(2018) L. F. Barros et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal control of astrocytic respiration through a variant of the Crabtree effect

(2018) Ignacio Fernández-Moncada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

(2018) Lee J. Sweetlove et al.   Nature Communications

Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity

(2018) Jimmy Zhang et al.   Cell Reports

Four Key Steps Control Glycolytic Flux in Mammalian Cells

(2018) Lukas Bahati Tanner et al.   Cell Systems

NBCe1 mediates the regulation of the NADH/NAD+ redox state in cortical astrocytes by neuronal signals

(2018) Susanne Köhler et al.   GLIA

Non-Canonical Control of Neuronal Energy Status by the Na+ Pump

(2018) Felipe Baeza-Lehnert et al.   Cell Metabolism

Brain Glucose Metabolism: Integration of Energetics with Function

(2018) Gerald A. Dienel   PHYSIOLOGICAL REVIEWS

Astrocytic and neuronal oxidative metabolism are coupled to the rate of glutamate-glutamine cycle in the tree shrew visual cortex

(2017) Sarah Sonnay et al.   GLIA

Current technical approaches to brain energy metabolism

(2017) L. Felipe Barros et al.   GLIA

Nanomolar nitric oxide concentrations quickly and reversibly modulate astrocytic energy metabolism

(2017) Alejandro San Martín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tight coupling of astrocyte energy metabolism to synaptic activity revealed by genetically encoded FRET nanosensors in hippocampal tissue

(2017) Iván Ruminot et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction

(2017) Yuri Zilberter et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Near-critical GLUT1 and Neurodegeneration

(2017) L. Felipe Barros et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

GLUT4 Mobilization Supports Energetic Demands of Active Synapses

(2017) Ghazaleh Ashrafi et al.   NEURON

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress

(2017) Meiyan Jin et al.   Cell Reports

Glycogen distribution in the microwave-fixed mouse brain reveals heterogeneous astrocytic patterns

(2016) Yuki Oe et al.   GLIA

Extrusion versus diffusion: mechanisms for recovery from sodium loads in mouse CA1 pyramidal neurons

(2016) Miguel A. Mondragão et al.   JOURNAL OF PHYSIOLOGY-LONDON

Substrate channelling as an approach to cascade reactions

(2016) Ian Wheeldon et al.   Nature Chemistry

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function

(2016) SoRi Jang et al.   NEURON

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hemichannel-mediated release of lactate

(2015) Anastassios Karagiannis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Channel-Mediated Lactate Release by K+-Stimulated Astrocytes

(2015) T. Sotelo-Hitschfeld et al.   JOURNAL OF NEUROSCIENCE

Integrating Proteomics and Enzyme Kinetics Reveals Tissue-Specific Types of the Glycolytic and Gluconeogenic Pathways

(2015) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

NH4+ triggers the release of astrocytic lactate via mitochondrial pyruvate shunting

(2015) Rodrigo Lerchundi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-preferential fuelling of the Na+/K+-ATPase pump

(2014) Ignacio Fernández-Moncada et al.   BIOCHEMICAL JOURNAL

Protein moonlighting in iron metabolism: glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

(2014) Vishant Mahendra Boradia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neurons Have an Active Glycogen Metabolism that Contributes to Tolerance to Hypoxia

(2014) Isabel Saez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Displacing hexokinase from mitochondrial voltage-dependent anion channel impairs GLT-1-mediated glutamate uptake but does not disrupt interactions between GLT-1 and mitochondrial proteins

(2014) Joshua G. Jackson et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cerebral glycolysis: a century of persistent misunderstanding and misconception

(2014) Avital Schurr   Frontiers in Neuroscience

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Diffusion of d-glucose measured in the cytosol of a single astrocyte

(2012) Marko Kreft et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Acute feedback control of astrocytic glycolysis by lactate

(2012) T. Sotelo-Hitschfeld et al.   GLIA

Quantitative Importance of the Pentose Phosphate Pathway Determined by Incorporation of 13C from [2-13C]- and [3-13C]Glucose into TCA Cycle Intermediates and Neurotransmitter Amino Acids in Functionally Intact Neurons

(2012) Eva M F Brekke et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

Fast and Reversible Stimulation of Astrocytic Glycolysis by K+ and a Delayed and Persistent Effect of Glutamate

(2011) C. X. Bittner et al.   JOURNAL OF NEUROSCIENCE

NBCe1 Mediates the Acute Stimulation of Astrocytic Glycolysis by Extracellular K+

(2011) I. Ruminot et al.   JOURNAL OF NEUROSCIENCE

Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria

(2011) E. N. Genda et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Regulation of Surface Glucose Transporter-3

(2011) J. M. Ferreira et al.   JOURNAL OF NEUROSCIENCE

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

(2010) Thomas Misje Mathiisen et al.   GLIA

Na+-Ca2+cosignaling in the stimulation of the glucose transporter GLUT1 in cultured astrocytes

(2007) Omar H. Porras et al.   GLIA