Fungal persister cells: The basis for recalcitrant infections?

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

(2018) Anuradha Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ras hyperactivation versus overexpression: Lessons from Ras dynamics in Candida albicans

(2018) Vavilala A. Pratyusha et al.   Scientific Reports

Development and regulation of single- and multi-species Candida albicans biofilms

(2017) Matthew B. Lohse et al.   NATURE REVIEWS MICROBIOLOGY

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras

(2017) Ken Peeters et al.   Nature Communications

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

(2017) Anuradha Chowdhary et al.   PLoS Pathogens

Comparative Ploidy Proteomics ofCandida albicansBiofilms Unraveled the Role of theAHP1Gene in the Biofilm Persistence Against Amphotericin B

(2016) Thuyen Truong et al.   MOLECULAR & CELLULAR PROTEOMICS

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

The Extracellular Matrix of Candida albicans Biofilms Impairs Formation of Neutrophil Extracellular Traps

(2016) Chad J. Johnson et al.   PLoS Pathogens

A common mechanism involving the TORC1 pathway can lead to amphotericin B-persistence in biofilm and planktonic Saccharomyces cerevisiae populations

(2016) Rasmus Bojsen et al.   Scientific Reports

Delicate Metabolic Control and Coordinated Stress Response Critically Determine Antifungal Tolerance of Candida albicans Biofilm Persisters

(2015) Peng Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biofilms: An Underappreciated Mechanism of Treatment Failure and Recurrence in Vaginal Infections: Table 1.

(2015) Christina A. Muzny et al.   CLINICAL INFECTIOUS DISEASES

Defining the frontiers between antifungal resistance, tolerance and the concept of persistence

(2015) Eric Delarze et al.   DRUG RESISTANCE UPDATES

Candida albicans Amphotericin B-Tolerant Persister Formation is Closely Related to Surface Adhesion

(2015) Jing Sun et al.   MYCOPATHOLOGIA

Infiltration of Matrix-Non-producers Weakens the Salmonella Biofilm and Impairs Its Antimicrobial Tolerance and Pathogenicity

(2015) Chakravarthy S. Srinandan et al.   Frontiers in Microbiology

Saccharomyces cerevisiae biofilm tolerance towards systemic antifungals depends on growth phase

(2014) Rasmus Bojsen et al.   BMC MICROBIOLOGY

Current status of antifungal resistance and its impact on clinical practice

(2014) Laura Alcazar-Fuoli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Amphotericin forms an extramembranous and fungicidal sterol sponge

(2014) Thomas M Anderson et al.   Nature Chemical Biology

A neglected epidemic: fungal infections in HIV/AIDS

(2014) Darius Armstrong-James et al.   TRENDS IN MICROBIOLOGY

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

Update on antifungal resistance in Aspergillus and Candida

(2013) M.C. Arendrup   CLINICAL MICROBIOLOGY AND INFECTION

Recent insights into Candida albicans biofilm resistance mechanisms

(2013) Lotte Mathé et al.   CURRENT GENETICS

The Eagle-like effect of echinocandins: what’s in a name?

(2013) Kim Vanstraelen et al.   Expert Review of Anti-Infective Therapy

Aging and cell death in the other yeasts,Schizosaccharomyces pombeandCandida albicans

(2013) Su-Ju Lin et al.   FEMS YEAST RESEARCH

Activated ClpP kills persisters and eradicates a chronic biofilm infection

(2013) B. P. Conlon et al.   NATURE

A problem of persistence: still more questions than answers?

(2013) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

(2013) Benjamin Matteson Vincent et al.   PLOS BIOLOGY

Caspofungin Kills Candida albicans by Causing both Cellular Apoptosis and Necrosis

(2012) Binghua Hao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of Treatment Strategy on Outcomes in Patients with Candidemia and Other Forms of Invasive Candidiasis: A Patient-Level Quantitative Review of Randomized Trials

(2012) D. R. Andes et al.   CLINICAL INFECTIOUS DISEASES

Risk Factors and Outcomes of Candidemia Caused by Biofilm-Forming Isolates in a Tertiary Care Hospital

(2012) Mario Tumbarello et al.   PLoS One

Small but Crucial: The Novel Small Heat Shock Protein Hsp21 Mediates Stress Adaptation and Virulence in Candida albicans

(2012) François L. Mayer et al.   PLoS One

Superoxide Dismutases Are Involved in Candida albicans Biofilm Persistence against Miconazole

(2011) Anna Bink et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hsp90 Governs Dispersion and Drug Resistance of Fungal Biofilms

(2011) Nicole Robbins et al.   PLoS Pathogens

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Role of Fks1p and Matrix Glucan in Candida albicans Biofilm Resistance to an Echinocandin, Pyrimidine, and Polyene

(2010) J. E. Nett et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fungicidal activity of miconazole against Candida spp. biofilms

(2010) Davy Vandenbosch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of Candida albicans

(2009) M. D. LaFleur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hsp90 Orchestrates Temperature-Dependent Candida albicans Morphogenesis via Ras1-PKA Signaling

(2009) Rebecca S. Shapiro et al.   CURRENT BIOLOGY

New triazoles and echinocandins: mode of action,in vitroactivity and mechanisms of resistance

(2009) Maria Teresa Fera et al.   Expert Review of Anti-Infective Therapy

Apoptosis in Candida biofilms exposed to amphotericin B

(2009) R. S. Al-Dhaheri et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

(2009) Sheena D. Singh et al.   PLoS Pathogens

Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans

(2009) Christopher Askew et al.   PLoS Pathogens

Absence of Amphotericin B-Tolerant Persister Cells in Biofilms of Some Candida Species

(2008) R. S. Al-Dhaheri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Candida albicans cells lacking CaMCA1-encoded metacaspase show resistance to oxidative stress-induced death and change in energy metabolism

(2008) YingYing Cao et al.   FUNGAL GENETICS AND BIOLOGY

The activity of the glyoxylate cycle in peroxisomes of Candida albicans depends on a functional  -oxidation pathway: evidence for reduced metabolite transport across the peroxisomal membrane

(2008) K. Piekarska et al.   MICROBIOLOGY-SGM

A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases

(2007) Harald Kusch et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY