Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

E-cadherin is required for metastasis in multiple models of breast cancer

(2019) Veena Padmanaban et al.   NATURE

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure

(2018) Alessia Visconti et al.   Nature Communications

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21

(2018) Quinn T. Ostrom et al.   Scientific Reports

Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk

(2018) Sivaramakrishna Rachakonda et al.   GENES CHROMOSOMES & CANCER

Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

(2018) Yan Zhang et al.   NATURE GENETICS

Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

(2018) Tongwu Zhang et al.   GENOME RESEARCH

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

(2018) David L. Duffy et al.   Nature Communications

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal

(2017) Dayana A Delgado et al.   JOURNAL OF MEDICAL GENETICS

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

(2017) Beatrice S Melin et al.   NATURE GENETICS

A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF

(2017) Jiyeon Choi et al.   NATURE GENETICS

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma

(2017) Katherine J. Ransohoff et al.   Oncotarget

Colocalization of GWAS and eQTL Signals Detects Target Genes

(2016) Farhad Hormozdiari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Bach Family of Transcription Factors: A Comprehensive Review

(2016) Yin Zhou et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

(2016) Ying Jin et al.   NATURE GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Increased Risk of Melanoma in Organ Transplant Recipients: Systematic Review and Meta-analysis of Cohort Studies

(2015) A Green et al.   ACTA DERMATO-VENEREOLOGICA

Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database

(2015) Kyriaki Antonopoulou et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Altered E-Cadherin Levels and Distribution in Melanocytes Precede Clinical Manifestations of Vitiligo

(2015) Roselyne Y. Wagner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF

(2015) Tamar Golan et al.   MOLECULAR CELL

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

(2015) Matthew H Law et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Hereditary Diffuse Gastric Cancer Syndrome

(2015) Samantha Hansford et al.   JAMA Oncology

Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma

(2014) Lauren G. Aoude et al.   JNCI-Journal of the National Cancer Institute

FOXD3 Modulates Migration through Direct Transcriptional Repression of TWIST1 in Melanoma

(2014) M. B. Weiss et al.   MOLECULAR CANCER RESEARCH

POT1 loss-of-function variants predispose to familial melanoma

(2014) Carla Daniela Robles-Espinoza et al.   NATURE GENETICS

Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma

(2014) Jianxin Shi et al.   NATURE GENETICS

Genetic variants in PARP1 (rs3219090) and IRF4(rs12203592) genes associated with melanoma susceptibility in a Spanish population

(2013) Maria Peña-Chilet et al.   BMC CANCER

SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis

(2013) J. C. Cronin et al.   CANCER RESEARCH

A variant in FTO shows association with melanoma risk not due to BMI

(2013) Mark M Iles et al.   NATURE GENETICS

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

(2012) Ying Jin et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Multiple Primary Cutaneous Melanomas in Li-Fraumeni Syndrome

(2011) Clara Curiel-Lewandrowski et al.   ARCHIVES OF DERMATOLOGY

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma†

(2011) Christopher I. Amos et al.   HUMAN MOLECULAR GENETICS

Meta-Analysis Combining New and Existing Data Sets Confirms that the TERT–CLPTM1L Locus Influences Melanoma Risk

(2011) Matthew H. Law et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

(2011) Satoru Yokoyama et al.   NATURE

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

(2011) Corine Bertolotto et al.   NATURE

Genome-wide association study identifies three new melanoma susceptibility loci

(2011) Jennifer H Barrett et al.   NATURE GENETICS

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

(2011) Stuart MacGregor et al.   NATURE GENETICS

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

Direct Reprogramming of Melanocytes to Neural Crest Stem-Like Cells by One Defined Factor

(2011) Susan E. Zabierowski et al.   STEM CELLS

IRF4 Variants Have Age-Specific Effects on Nevus Count and Predispose to Melanoma

(2010) David L. Duffy et al.   AMERICAN JOURNAL OF HUMAN GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Familial Melanoma: A Meta-analysis and Estimates of Attributable Fraction

(2010) C. M. Olsen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Estimating the Attributable Fraction for Cancer: A Meta-analysis of Nevi and Melanoma

(2010) C. M. Olsen et al.   Cancer Prevention Research

FOXD3 Is a Mutant B-RAF–Regulated Inhibitor of G1-S Progression in Melanoma Cells

(2010) Ethan V. Abel et al.   CANCER RESEARCH

Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest

(2010) Kevin Curran et al.   DEVELOPMENTAL BIOLOGY

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Estimating the attributable fraction for melanoma: A meta-analysis of pigmentary characteristics and freckling

(2010) Catherine M. Olsen et al.   INTERNATIONAL JOURNAL OF CANCER

FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism

(2009) A. J. Thomas et al.   DEVELOPMENT

Multiple Pigmentation Gene Polymorphisms Account for a Substantial Proportion of Risk of Cutaneous Malignant Melanoma

(2009) David L. Duffy et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A review of human carcinogens—Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish

(2009) Béatrice Secretan et al.   LANCET ONCOLOGY

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi

(2009) Mario Falchi et al.   NATURE GENETICS

Genome-wide association study identifies three loci associated with melanoma risk

(2009) D Timothy Bishop et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Transgenic expression of Notch in melanocytes demonstrates RBP-Jκ-dependent signaling

(2009) Karine Schouwey et al.   Pigment Cell & Melanoma Research

A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

(2008) Yu-mei Chang et al.   INTERNATIONAL JOURNAL OF CANCER

A Prospective Study of Telomere Length and the Risk of Skin Cancer

(2008) Jiali Han et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

(2008)   NATURE GENETICS

Common sequence variants on 20q11.22 confer melanoma susceptibility

(2008) Kevin M Brown et al.   NATURE GENETICS