Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database

(2015) Kyriaki Antonopoulou et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions

(2014) Jennifer H. Barrett et al.   INTERNATIONAL JOURNAL OF CANCER

The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

(2014) Mark M. Iles et al.   JNCI-Journal of the National Cancer Institute

POT1 loss-of-function variants predispose to familial melanoma

(2014) Carla Daniela Robles-Espinoza et al.   NATURE GENETICS

Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma

(2014) Jianxin Shi et al.   NATURE GENETICS

Loss ofCDKN2Aexpression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

(2014) Richard J. Young et al.   Pigment Cell & Melanoma Research

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

(2013) Juliet D. French et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Beyond GWASs: Illuminating the Dark Road from Association to Function

(2013) Stacey L. Edwards et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variants in PARP1 (rs3219090) and IRF4(rs12203592) genes associated with melanoma susceptibility in a Spanish population

(2013) Maria Peña-Chilet et al.   BMC CANCER

A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway

(2013) Christian Praetorius et al.   CELL

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans

(2013) Mingfeng Zhang et al.   HUMAN MOLECULAR GENETICS

A variant in FTO shows association with melanoma risk not due to BMI

(2013) Mark M Iles et al.   NATURE GENETICS

Identification of seven loci affecting mean telomere length and their association with disease

(2013) Veryan Codd et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Telomere Length and the Risk of Cutaneous Malignant Melanoma in Melanoma-Prone Families with and without CDKN2A Mutations

(2013) Laura S. Burke et al.   PLoS One

Quantitative assessment of the influence of CYP1B1 polymorphisms and head and neck squamous cell carcinoma risk

(2013) Ming Shen et al.   TUMOR BIOLOGY

CYP1B1 and hormone-induced cancer

(2012) Ketan Gajjar et al.   CANCER LETTERS

Further development of forensic eye color predictive tests

(2012) Y. Ruiz et al.   Forensic Science International-Genetics

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells

(2012) Silvia Brambillasca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomerase Reverse Transcriptase Locus Polymorphisms and Cancer Risk: A Field Synopsis and Meta-Analysis

(2012) Simone Mocellin et al.   JNCI-Journal of the National Cancer Institute

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

(2012) K. Hoffmeyer et al.   SCIENCE

The role of CCND1 alterations during the progression of cutaneous malignant melanoma

(2012) Laura Vízkeleti et al.   TUMOR BIOLOGY

The Anterior Gradient Homolog 3 (AGR3) Gene Is Associated With Differentiation and Survival in Ovarian Cancer

(2011) Erin R. King et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q

(2011) Craig Teerlink et al.   HUMAN GENETICS

Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets

(2011) Miao-Xin Li et al.   HUMAN GENETICS

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma†

(2011) Christopher I. Amos et al.   HUMAN MOLECULAR GENETICS

Meta-Analysis Combining New and Existing Data Sets Confirms that the TERT–CLPTM1L Locus Influences Melanoma Risk

(2011) Matthew H. Law et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide association study identifies three new melanoma susceptibility loci

(2011) Jennifer H Barrett et al.   NATURE GENETICS

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

(2011) Stuart MacGregor et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

(2011) Alexandra C. Nica et al.   PLoS Genetics

IRF4 Variants Have Age-Specific Effects on Nevus Count and Predispose to Melanoma

(2010) David L. Duffy et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

GWAMA: software for genome-wide association meta-analysis

(2010) Reedik Mägi et al.   BMC BIOINFORMATICS

Melanocytic Nevi, Nevus Genes, and Melanoma Risk in a Large Case-Control Study in the United Kingdom

(2010) J. A. Newton-Bishop et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

No Association between TERT-CLPTM1L Single Nucleotide Polymorphism rs401681 and Mean Telomere Length or Cancer Risk

(2010) K. A. Pooley et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate

(2010) Julia A. Newton-Bishop et al.   EUROPEAN JOURNAL OF CANCER

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Genetic variants in telomere-maintaining genes and skin cancer risk

(2010) Hongmei Nan et al.   HUMAN GENETICS

Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N6-threonylcarbamoyladenosine in tRNA

(2010) Simon Arragain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Krüppel-Like Transcription Factor 4 Contributes to Maintenance of Telomerase Activity in Stem Cells

(2010) Chui-Wei Wong et al.   STEM CELLS

Genotype Imputation

(2009) Yun Li et al.   Annual Review of Genomics and Human Genetics

Serum 25-Hydroxyvitamin D3 Levels Are Associated With Breslow Thickness at Presentation and Survival From Melanoma

(2009) Julia A. Newton-Bishop et al.   JOURNAL OF CLINICAL ONCOLOGY

RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway

(2009) Yasuyuki Miyake et al.   MOLECULAR CELL

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi

(2009) Mario Falchi et al.   NATURE GENETICS

Genome-wide association study identifies three loci associated with melanoma risk

(2009) D Timothy Bishop et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

(2008) P. I.W. de Bakker et al.   HUMAN MOLECULAR GENETICS

A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes

(2008) Yu-mei Chang et al.   INTERNATIONAL JOURNAL OF CANCER

A Prospective Study of Telomere Length and the Risk of Skin Cancer

(2008) Jiali Han et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Common sequence variants on 20q11.22 confer melanoma susceptibility

(2008) Kevin M Brown et al.   NATURE GENETICS

ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

(2008) Jiali Han et al.   PLoS Genetics