Non-additive (dominance) effects of genetic variants associated with refractive error and myopia

Cohort profile: design and methods in the eye and vision consortium of UK Biobank

(2019) Sharon Yu Lin Chua et al.   BMJ Open

Interaction between lifestyle and genetic susceptibility in myopia: the Generation R study

(2019) Clair A. Enthoven et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

A commonly occurring genetic variant within the NPLOC4–TSPAN10–PDE6G gene cluster is associated with the risk of strabismus

(2019) Denis Plotnikov et al.   HUMAN GENETICS

Association Between Polygenic Risk Score and Risk of Myopia

(2019) Neema Ghorbani Mojarrad et al.   JAMA Ophthalmology

Global prevalence of visual impairment associated with myopic macular degeneration and temporal trends from 2000 through 2050: systematic review, meta-analysis and modelling

(2018) Timothy R Fricke et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

(2018) Milly S. Tedja et al.   NATURE GENETICS

Education and myopia: assessing the direction of causality by mendelian randomisation

(2018) Edward Mountjoy et al.   BMJ-British Medical Journal

Education and myopia: assessing the direction of causality by mendelian randomisation

(2018) Edward Mountjoy et al.   BMJ-British Medical Journal

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci

(2018) Rupal L. Shah et al.   HUMAN GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Clinical and molecular genetic analysis of a family with late-onset LAMA2-related muscular dystrophy

(2016) Juan Ding et al.   BRAIN & DEVELOPMENT

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively

(2016) Andrew R. Wood et al.   DIABETOLOGIA

The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis

(2016) Wen Huang et al.   PLoS Genetics

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

(2016) Qiao Fan et al.   Scientific Reports

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

(2015) Zhihong Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

(2015) Tobias L Lenz et al.   NATURE GENETICS

Frequency and Distribution of Refractive Error in Adult Life: Methodology and Findings of the UK Biobank Study

(2015) Phillippa M. Cumberland et al.   PLoS One

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Statistical power and significance testing in large-scale genetic studies

(2014) Pak C. Sham et al.   NATURE REVIEWS GENETICS

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

(2013) Virginie J M Verhoeven et al.   NATURE GENETICS

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

(2013) Amy K. Kiefer et al.   PLoS Genetics

Myopia

(2012) Ian G Morgan et al.   LANCET

The Heritability of Ocular Traits

(2010) Paul G. Sanfilippo et al.   SURVEY OF OPHTHALMOLOGY