The emerging role of the long non-coding RNA HOTAIR in breast cancer development and treatment
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Title
The emerging role of the long non-coding RNA HOTAIR in breast cancer development and treatment
Authors
Keywords
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Journal
Journal of Translational Medicine
Volume 18, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-04-03
DOI
10.1186/s12967-020-02320-0
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Note: Only part of the references are listed.- Long non-coding RNA GAS5 regulates the growth and metastasis of human cervical cancer cells via induction of apoptosis and cell cycle arrest
- (2020) Zhang Yan et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency
- (2019) Weisi Lu et al. Stem Cell Research & Therapy
- The Role of Noncoding RNAs in Double-Strand Break Repair
- (2019) Nathalie Durut et al. Frontiers in Plant Science
- nab-Paclitaxel plus carboplatin or gemcitabine versus gemcitabine plus carboplatin as first-line treatment of patients with triple-negative metastatic breast cancer: results from the tnAcity trial
- (2018) D A Yardley et al. ANNALS OF ONCOLOGY
- Decreased BRMS1L expression is correlated with glioma grade and predicts poor survival in glioblastoma via an invasive phenotype
- (2018) Jia Lv et al. Cancer Biomarkers
- LncRNA HOTAIR is a Prognostic Biomarker for the Proliferation and Chemoresistance of Colorectal Cancer via MiR-203a-3p-Mediated Wnt/ß-Catenin Signaling Pathway
- (2018) Zhigang Xiao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Estrogen receptor β promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network
- (2018) Jie Ding et al. ONCOGENE
- LncRNA HOTAIR influences cell growth, migration, invasion, and apoptosis via the miR-20a-5p/HMGA2 axis in breast cancer
- (2018) Wenyan Zhao et al. Cancer Medicine
- The regulatory roles of lncRNAs in the process of breast cancer invasion and metastasis
- (2018) Siying Zhou et al. BIOSCIENCE REPORTS
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Downregulation of Long Noncoding RNA HOTAIR and EZH2 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Human Breast Cancer Cells
- (2018) Lu Han et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression
- (2018) Ning Li et al. Radiation Oncology
- HOTAIR but not ANRIL long non-coding RNA contributes to the pathogenesis of multiple sclerosis
- (2017) Majid Pahlevan Kakhki et al. IMMUNOLOGY
- HOTAIR role in melanoma progression and its identification in the blood of patients with advanced disease
- (2017) Monica Cantile et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Knockdown of Hotair suppresses proliferation and cell cycle progression in hepatocellular carcinoma cell by downregulating CCND1 expression
- (2017) Jia-Jia Zhou et al. Molecular Medicine Reports
- Non-coding RNA: A protective role for TERRA at telomeres
- (2017) Linda Koch NATURE REVIEWS GENETICS
- Genetic polymorphisms of HOTAIR gene are associated with the risk of breast cancer in a sample of southeast Iranian population
- (2017) Shekoufeh Hassanzarei et al. TUMOR BIOLOGY
- Long non-coding RNA HOTAIR enhances radioresistance in MDA-MB231 breast cancer cells
- (2017) Yun Zhou et al. Oncology Letters
- Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer
- (2017) Ali R. Özeş et al. Scientific Reports
- Downregulation of miRNA-141 in breast cancer cells is associated with cell migration and invasion: involvement of ANP32E targeting
- (2017) Ping Li et al. Cancer Medicine
- lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer
- (2017) Peilong Li et al. Molecular Therapy-Nucleic Acids
- Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells
- (2017) Jia Deng et al. PLoS One
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- Long Noncoding RNA HOTAIR Modulates MiR-206-mediated Bcl-w Signaling to Facilitate Cell Proliferation in Breast Cancer
- (2017) Wei Ding et al. Scientific Reports
- Analysis of the association of HOTAIR single nucleotide polymorphism (rs920778) and risk of cervical cancer
- (2016) Haifeng Qiu et al. APMIS
- Delphinidin-3-glucoside suppresses breast carcinogenesis by inactivating the Akt/HOTAIR signaling pathway
- (2016) Xiaohong Yang et al. BMC CANCER
- Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules
- (2016) Zoi Piperigkou et al. MATRIX BIOLOGY
- The long noncoding RNA HOTAIR activates autophagy by upregulating ATG3 and ATG7 in hepatocellular carcinoma
- (2016) Liang Yang et al. Molecular BioSystems
- NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
- (2016) A R Özeş et al. ONCOGENE
- The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
- (2016) C Battistelli et al. ONCOGENE
- LncRNA HOTAIR promotes cisplatin resistance in gastric cancer by targeting miR-126 to activate the PI3K/AKT/MRP1 genes
- (2016) Jin Yan et al. TUMOR BIOLOGY
- Identification of genetic variation in the lncRNA HOTAIR associated with HPV16-related cervical cancer pathogenesis
- (2016) Sweta Sharma Saha et al. CELLULAR ONCOLOGY
- Epigenetic modification of miR-141 regulates SKA2 by an endogenous ‘sponge’ HOTAIR in glioma
- (2016) Er-Bao Bian et al. Oncotarget
- A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?
- (2016) Licia Selleri et al. PLoS Genetics
- HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
- (2015) Yinghui Li et al. CANCER RESEARCH
- Calycosin and Genistein Induce Apoptosis by Inactivation of HOTAIR/p-Akt Signaling Pathway in Human Breast Cancer MCF-7 Cells
- (2015) Jian Chen et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer
- (2015) Sifeng Tao et al. Journal of Translational Medicine
- Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells
- (2015) Shun Fang et al. LABORATORY INVESTIGATION
- HOTAIR Forms an Intricate and Modular Secondary Structure
- (2015) Srinivas Somarowthu et al. MOLECULAR CELL
- HOTAIR is a potential target for the treatment of cisplatin-resistant ovarian cancer
- (2015) YU WANG et al. Molecular Medicine Reports
- LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
- (2015) X Xue et al. ONCOGENE
- Knockdown of long non-coding RNA HOTAIR inhibits proliferation and invasiveness and improves radiosensitivity in colorectal cancer
- (2015) XIAO-DONG YANG et al. ONCOLOGY REPORTS
- Breast Cancer: Radiogenomic Biomarker Reveals Associations among Dynamic Contrast-enhanced MR Imaging, Long Noncoding RNA, and Metastasis
- (2015) Shota Yamamoto et al. RADIOLOGY
- Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract
- (2015) Yi Liu et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Effect of HOTAIR rs920778 polymorphism on breast cancer susceptibility and clinicopathologic features in a Turkish population
- (2015) Süleyman Bayram et al. TUMOR BIOLOGY
- The long non-coding RNA HOTAIR affects the radiosensitivity of pancreatic ductal adenocarcinoma by regulating the expression of Wnt inhibitory factor 1
- (2015) Yanhui Jiang et al. TUMOR BIOLOGY
- A functional HOTAIR rs12826786 C>T polymorphism is associated with breast cancer susceptibility and poor clinicopathological characteristics in a Turkish population: a hospital-based case–control study
- (2015) Süleyman Bayram et al. TUMOR BIOLOGY
- Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer
- (2015) Jing Li et al. TUMOR BIOLOGY
- Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326
- (2015) Jing Ke et al. Oncotarget
- LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer
- (2015) Ali Zhang et al. Cell Reports
- HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer
- (2015) Andrew E. Teschendorff et al. Genome Medicine
- HOTAIR Interacting with MAPK1 Regulates Ovarian Cancer skov3 Cell Proliferation, Migration, and Invasion
- (2015) Tang Yiwei et al. MEDICAL SCIENCE MONITOR
- Digital Quantitation of Potential Therapeutic Target RNAs
- (2015) David W. Dodd et al. Nucleic Acid Therapeutics
- Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes
- (2015) Xiaoping Su et al. Oncotarget
- The identification of an ESCC susceptibility SNP rs920778 that regulates the expression of lncRNAHOTAIRvia a novel intronic enhancer
- (2014) Xiaojiao Zhang et al. CARCINOGENESIS
- Non-coding RNAs: biological functions and applications
- (2014) Baby Santosh et al. CELL BIOCHEMISTRY AND FUNCTION
- Long Noncoding RNAs: Emerging Stars in Gene Regulation, Epigenetics and Human Disease
- (2014) Arunoday Bhan et al. ChemMedChem
- Long Non-Coding RNA HOTAIR Promotes Cell Migration and Invasion via Down-Regulation of RNA Binding Motif Protein 38 in Hepatocellular Carcinoma Cells
- (2014) Chaofeng Ding et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Long non-coding RNA HOTAIR is associated with human cervical cancer progression
- (2014) HEE JUNG KIM et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Long Non-coding RNAHOTAIRIs Targeted and Regulated by miR-141 in Human Cancer Cells
- (2014) Takeshi Chiyomaru et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functions of lncRNA HOTAIR in lung cancer
- (2014) Gregory Loewen et al. Journal of Hematology & Oncology
- Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo
- (2014) Arunoday Bhan et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer
- (2014) Ming-zhe Ma et al. Molecular Cancer
- Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer
- (2014) Xiang-hua Liu et al. Molecular Cancer
- The Long Non-Coding HOTAIR Is Modulated by Cyclic Stretch and WNT/β-CATENIN in Human Aortic Valve Cells and Is a Novel Repressor of Calcification Genes
- (2014) Katrina Carrion et al. PLoS One
- MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway
- (2014) Hongyi Zhang et al. STEM CELLS
- HOTAIR enhanced aggressive biological behaviors and induced radio-resistance via inhibiting p21 in cervical cancer
- (2014) Li Jing et al. TUMOR BIOLOGY
- Long noncoding RNA HOTAIR involvement in cancer
- (2014) Yansheng Wu et al. TUMOR BIOLOGY
- Binding Interactions between Long Noncoding RNA HOTAIR and PRC2 Proteins
- (2013) Liang Wu et al. BIOCHEMISTRY
- Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer
- (2013) Kristina P. Sørensen et al. BREAST CANCER RESEARCH AND TREATMENT
- Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
- (2013) Eunhee Kim et al. CANCER CELL
- Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
- (2013) E. M. Dijkgraaf et al. CANCER RESEARCH
- EZH2 takes the stage when BRCA1 loses
- (2013) Lan Wang et al. CELL CYCLE
- BRCA1 is a negative modulator of the PRC2 complex
- (2013) Lan Wang et al. EMBO JOURNAL
- Antisense Transcript Long Noncoding RNA (lncRNA) HOTAIR is Transcriptionally Induced by Estradiol
- (2013) Arunoday Bhan et al. JOURNAL OF MOLECULAR BIOLOGY
- The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21WAF1/CIP1 Expression
- (2013) Zhili Liu et al. PLoS One
- Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
- (2013) Je-Hyun Yoon et al. Nature Communications
- Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression
- (2013) Lingjie Li et al. Cell Reports
- Long Intergenic Noncoding RNA HOTAIR Is Overexpressed and Regulates PTEN Methylation in Laryngeal Squamous Cell Carcinoma
- (2012) Dandan Li et al. AMERICAN JOURNAL OF PATHOLOGY
- Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer
- (2012) Lingeng Lu et al. BREAST CANCER RESEARCH AND TREATMENT
- Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma
- (2012) MASAHISA ISHIBASHI et al. ONCOLOGY REPORTS
- The sequence, structure and evolutionary features of HOTAIR in mammals
- (2011) Sha He et al. BMC EVOLUTIONARY BIOLOGY
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human
- (2011) Patrick Schorderet et al. PLoS Genetics
- Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
- (2010) Rajnish A. Gupta et al. NATURE
- miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
- (2010) Li Ma et al. NATURE CELL BIOLOGY
- Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
- (2010) M.-C. Tsai et al. SCIENCE
- AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2
- (2009) Hana Kim et al. NUCLEIC ACIDS RESEARCH
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