The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition

Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29

(2015) Carla Cicchini et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development

(2015) C.-L. Tien et al.   DEVELOPMENT

Tumor-secreted Hsp90 Subverts Polycomb Function to Drive Prostate Tumor Growth and Invasion

(2015) Krystal D. Nolan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes

(2015) Patompon Wongtrakoongate et al.   PLoS Genetics

Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells

(2014) J. Chen et al.   CANCER RESEARCH

Functional interplay between MyoD and CTCF in regulating long-range chromatin interactions during differentiation

(2014) C. Battistelli et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte

(2014) Carla Cicchini et al.   LIVER INTERNATIONAL

EZH2: Not EZHY (Easy) to Deal

(2014) Gauri Deb et al.   MOLECULAR CANCER RESEARCH

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

(2014) Catherine Cifuentes-Rojas et al.   MOLECULAR CELL

RNA Binding of PRC2: Promiscuous or Well Ordered?

(2014) Markus Kretz et al.   MOLECULAR CELL

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long non-coding RNAHOTAIRis an independent prognostic marker for nasopharyngeal carcinoma progression and survival

(2013) Yan Nie et al.   CANCER SCIENCE

Large Intervening Non-Coding RNA HOTAIR is Associated with Hepatocellular Carcinoma Progression

(2013) YJ Geng et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

(2013) Syuzo Kaneko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

(2013) Sarah Javaid et al.   Cell Reports

Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression

(2013) Lingjie Li et al.   Cell Reports

Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting

(2012) P. Arnold et al.   GENOME RESEARCH

Early events in cell adhesion and polarity during epithelial-mesenchymal transition

(2012) R. Y.-J. Huang et al.   JOURNAL OF CELL SCIENCE

Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

(2011) Zhe Yang et al.   ANNALS OF SURGICAL ONCOLOGY

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs

(2011) F Garibaldi et al.   CELL DEATH AND DIFFERENTIATION

The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α

(2011) Laura Santangelo et al.   HEPATOLOGY

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

(2011) Oliver G McDonald et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Yeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis

(2009) Feng-Ming Lin et al.   EMBO JOURNAL

Convergence of Wnt Signaling on the HNF4α-Driven Transcription in Controlling Liver Zonation

(2009) Marta Colletti et al.   GASTROENTEROLOGY

Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays

(2009) Eugene Bolotin et al.   HEPATOLOGY

Distinct expression of polycomb group proteins EZH2 and BMI1 in hepatocellular carcinoma

(2009) Yutaka Yonemitsu et al.   HUMAN PATHOLOGY

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

(2008) M. Rodriguez et al.   CANCER RESEARCH

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

(2008) Satoshi Fujii et al.   CANCER SCIENCE

E2f6 and Bmi1 cooperate in axial skeletal development

(2008) Maria Courel et al.   DEVELOPMENTAL DYNAMICS

The LIM Protein AJUBA Recruits Protein Arginine Methyltransferase 5 To Mediate SNAIL-Dependent Transcriptional Repression

(2008) Z. Hou et al.   MOLECULAR AND CELLULAR BIOLOGY

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

(2008) Q Cao et al.   ONCOGENE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

TGFβ-induced EMT requires focal adhesion kinase (FAK) signaling

(2007) Carla Cicchini et al.   EXPERIMENTAL CELL RESEARCH