Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells

Downregulation of HOXA1 gene affects small cell lung cancer cell survival and chemoresistance under the regulation of miR-100

(2014) Faman Xiao et al.   EUROPEAN JOURNAL OF CANCER

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

(2014) Xiang-hua Liu et al.   Molecular Cancer

Long noncoding RNAHOTAIRis relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer

(2014) Hiroshi Ono et al.   Cancer Medicine

The Noncoding RNA Expression Profile and the Effect of lncRNA AK126698 on Cisplatin Resistance in Non-Small-Cell Lung Cancer Cell

(2013) Yong Yang et al.   PLoS One

The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21WAF1/CIP1 Expression

(2013) Zhili Liu et al.   PLoS One

Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing

(2012) F. Mohammad et al.   DEVELOPMENT

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

IGFBP-3 methylation-derived deficiency mediates the resistance to cisplatin through the activation of the IGFIR/Akt pathway in non-small cell lung cancer

(2012) M Cortés-Sempere et al.   ONCOGENE

Long non-coding RNAs and cancer: a new frontier of translational research?

(2012) R Spizzo et al.   ONCOGENE

Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma

(2012) Tian-Zhou Zha et al.   TUMOR BIOLOGY

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL

(2011) Vitaliy O. Kaminskyy et al.   CARCINOGENESIS

Small-cell lung cancer

(2011) Jan P van Meerbeeck et al.   LANCET

SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15

(2011) M Tessema et al.   ONCOGENE

Treatment options for small cell lung cancer – do we have more choice?

(2010) M Puglisi et al.   BRITISH JOURNAL OF CANCER

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer)

(2009) L Plowright et al.   BRITISH JOURNAL OF CANCER

IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer

(2009) I Ibanez de Caceres et al.   ONCOGENE

Transcriptional Activation of Signal Transducer and Activator of Transcription (STAT) 3 and STAT5B Partially Mediate Homeobox A1-Stimulated Oncogenic Transformation of the Immortalized Human Mammary Epithelial Cell

(2008) Kumarasamypet M. Mohankumar et al.   ENDOCRINOLOGY