NMDA receptor channel gating control by the pre-M1 helix

From bedside‐to‐bench: What disease‐associated variants are teaching us about the NMDA receptor

(2020) Johansen B. Amin et al.   JOURNAL OF PHYSIOLOGY-LONDON

A structurally-derived model of subunit-dependent NMDA receptor function

(2018) Alasdair Gibb et al.   JOURNAL OF PHYSIOLOGY-LONDON

Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells

(2018) Subhrajit Bhattacharya et al.   NEURON

Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor

(2018) Farzad Jalali-Yazdi et al.   CELL

Mapping the Conformational Landscape of Glutamate Receptors Using Single Molecule FRET

(2018) David M. MacLean et al.   TRENDS IN NEUROSCIENCES

Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors

(2018) Jin-Bao Zhang et al.   Cell Reports

GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function

(2017) Wenjuan Chen et al.   JOURNAL OF HUMAN GENETICS

Channel opening and gating mechanism in AMPA-subtype glutamate receptors

(2017) Edward C. Twomey et al.   NATURE

The structure–energy landscape of NMDA receptor gating

(2017) Drew M Dolino et al.   Nature Chemical Biology

PDBsum: Structural summaries of PDB entries

(2017) Roman A. Laskowski et al.   PROTEIN SCIENCE

Validation of Structures in the Protein Data Bank

(2017) Swanand Gore et al.   STRUCTURE

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

(2017) Kevin K. Ogden et al.   PLoS Genetics

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

(2016) Sharon A. Swanger et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Molecular Determinant of Subtype-Specific Desensitization in Ionotropic Glutamate Receptors

(2016) Matthew Alsaloum et al.   JOURNAL OF NEUROSCIENCE

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

(2016) Nami Tajima et al.   NATURE

Delineating the GRIN1 phenotypic spectrum

(2016) Johannes R. Lemke et al.   NEUROLOGY

Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs

(2016) Maria V. Yelshanskaya et al.   NEURON

The RING 2.0 web server for high quality residue interaction networks

(2016) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios

(2015) Xiaolin Zhu et al.   GENETICS IN MEDICINE

Context-Dependent GluN2B-Selective Inhibitors of NMDA Receptor Function Are Neuroprotective with Minimal Side Effects

(2015) Hongjie Yuan et al.   NEURON

Emerging structural insights into the function of ionotropic glutamate receptors

(2015) Erkan Karakas et al.   TRENDS IN BIOCHEMICAL SCIENCES

NMDA receptor structures reveal subunit arrangement and pore architecture

(2014) Chia-Hsueh Lee et al.   NATURE

Crystal structure of a heterotetrameric NMDA receptor ion channel

(2014) E. Karakas et al.   SCIENCE

GRIN2Bmutations in west syndrome and intellectual disability with focal epilepsy

(2013) Johannes R. Lemke et al.   ANNALS OF NEUROLOGY

De novo mutations in epileptic encephalopathies

(2013) et al.   NATURE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

GluN1 splice variant control of GluN1/GluN2D NMDA receptors

(2012) Katie M. Vance et al.   JOURNAL OF PHYSIOLOGY-LONDON

Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening

(2011) Iehab Talukder et al.   JOURNAL OF GENERAL PHYSIOLOGY

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Emerging Models of Glutamate Receptor Ion Channel Structure and Function

(2011) Mark L. Mayer   STRUCTURE

Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors

(2011) Katie M. Vance et al.   Nature Communications

Specific Sites within the Ligand-Binding Domain and Ion Channel Linkers Modulate NMDA Receptor Gating

(2010) I. Talukder et al.   JOURNAL OF NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

The Activation Gate and Gating Mechanism of the NMDA Receptor

(2008) H.-R. Chang et al.   JOURNAL OF NEUROSCIENCE

Activation of recombinant NR1/NR2C NMDA receptors

(2008) Shashank M. Dravid et al.   JOURNAL OF PHYSIOLOGY-LONDON