Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
Authors
Keywords
-
Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 217, Issue 6, Pages -
Publisher
Rockefeller University Press
Online
2020-04-06
DOI
10.1084/jem.20192362
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides
- (2020) Xiaoxiao Wan et al. NATURE IMMUNOLOGY
- Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy
- (2019) Imran Siddiqui et al. IMMUNITY
- The single-cell transcriptional landscape of mammalian organogenesis
- (2019) Junyue Cao et al. NATURE
- A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry
- (2019) Nicolas Damond et al. Cell Metabolism
- Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes
- (2019) Yue J. Wang et al. Cell Metabolism
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
- (2019) Francesca Alfei et al. NATURE
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
- (2019) Chen Yao et al. NATURE IMMUNOLOGY
- Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset
- (2019) Louis Gioia et al. Science Immunology
- Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice
- (2018) Javier A. Carrero et al. DIABETES
- Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes
- (2018) Jamie L. Felton et al. JOURNAL OF IMMUNOLOGY
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node
- (2018) Ruby Alonso et al. Nature Communications
- Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides
- (2018) Xiaoxiao Wan et al. NATURE
- Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production
- (2017) Elise Dalmas et al. IMMUNITY
- The islet-resident macrophage is in an inflammatory state and senses microbial products in blood
- (2017) Stephen T. Ferris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Origins, Recruitment, and Regulation of CD11c+Cells in Inflamed Islets of Autoimmune Diabetes Mice
- (2017) Joanna E. Klementowicz et al. JOURNAL OF IMMUNOLOGY
- Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection
- (2017) Samad A. Ibitokou et al. JOURNAL OF IMMUNOLOGY
- Reversed graph embedding resolves complex single-cell trajectories
- (2017) Xiaojie Qiu et al. NATURE METHODS
- Imaging the emergence and natural progression of spontaneous autoimmune diabetes
- (2017) James F. Mohan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
- (2017) Javier A. Carrero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Massively parallel digital transcriptional profiling of single cells
- (2017) Grace X. Y. Zheng et al. Nature Communications
- Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes
- (2016) Pia Leete et al. DIABETES
- T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections
- (2016) Daniel T. Utzschneider et al. IMMUNITY
- Expanding antigen-specific regulatory networks to treat autoimmunity
- (2016) Xavier Clemente-Casares et al. NATURE
- Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
- (2016) Se Jin Im et al. NATURE
- CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
- (2016) Lokesh A Kalekar et al. NATURE IMMUNOLOGY
- Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
- (2016) Jenny Aurielle B Babon et al. NATURE MEDICINE
- Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis
- (2016) Jean Fan et al. NATURE METHODS
- The pancreas anatomy conditions the origin and properties of resident macrophages
- (2015) Boris Calderon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Spatial reconstruction of single-cell gene expression data
- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor
- (2015) Gary E Grajales-Reyes et al. NATURE IMMUNOLOGY
- Phagocytosis of apoptotic cells in homeostasis
- (2015) Sanja Arandjelovic et al. NATURE IMMUNOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Population dynamics of islet-infiltrating cells in autoimmune diabetes
- (2015) Angela M. Magnuson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- A Minor Subset of Batf3-Dependent Antigen-Presenting Cells in Islets of Langerhans Is Essential for the Development of Autoimmune Diabetes
- (2014) Stephen T. Ferris et al. IMMUNITY
- Regulation of Alternative Macrophage Activation by Galectin-3
- (2014) A. C. MacKinnon et al. JOURNAL OF IMMUNOLOGY
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
- (2013) Joel Crespo et al. CURRENT OPINION IN IMMUNOLOGY
- The central role of antigen presentation in islets of Langerhans in autoimmune diabetes
- (2013) Boris Calderon et al. CURRENT OPINION IN IMMUNOLOGY
- CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity
- (2013) Yosuke Kumamoto et al. IMMUNITY
- Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children
- (2013) Anette G. Ziegler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- T Cells Are Essential Effectors of Type 1 Diabetes in the Nonobese Diabetic Mouse Model
- (2013) J. G. M. Markle et al. JOURNAL OF IMMUNOLOGY
- B Lymphocyte "Original Sin" in the Bone Marrow Enhances Islet Autoreactivity in Type 1 Diabetes-Prone Nonobese Diabetic Mice
- (2013) R. A. Henry-Bonami et al. JOURNAL OF IMMUNOLOGY
- Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse
- (2013) Javier A. Carrero et al. PLoS One
- Humoral Autoimmunity in Type 1 Diabetes: Prediction, Significance, and Detection of Distinct Disease Subtypes
- (2013) M. Pietropaolo et al. Cold Spring Harbor Perspectives in Medicine
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
- (2012) Travis A. Doering et al. IMMUNITY
- Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
- (2012) Shigeki Chiba et al. NATURE IMMUNOLOGY
- TNF Receptor 1 Deficiency Increases Regulatory T Cell Function in Nonobese Diabetic Mice
- (2011) J. Chee et al. JOURNAL OF IMMUNOLOGY
- Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response
- (2011) B. Calderon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans
- (2011) B. Calderon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis
- (2010) Vladislav Volarevic et al. AUTOIMMUNITY
- Isolated human islets contain a distinct population of mesenchymal stem cells
- (2010) Françoise Carlotti et al. Islets
- KLF2 Transcription-Factor Deficiency in T Cells Results in Unrestrained Cytokine Production and Upregulation of Bystander Chemokine Receptors
- (2009) Michael A. Weinreich et al. IMMUNITY
- Suppression of Autoimmune Diabetes by Soluble Galectin-1
- (2009) M. J. Perone et al. JOURNAL OF IMMUNOLOGY
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
- Insulin as an autoantigen in NOD/human diabetes
- (2008) Li Zhang et al. CURRENT OPINION IN IMMUNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started