The pancreas anatomy conditions the origin and properties of resident macrophages

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

A Minor Subset of Batf3-Dependent Antigen-Presenting Cells in Islets of Langerhans Is Essential for the Development of Autoimmune Diabetes

(2014) Stephen T. Ferris et al.   IMMUNITY

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Macrophage heterogeneity in tissues: phenotypic diversity and functions

(2014) Siamon Gordon et al.   IMMUNOLOGICAL REVIEWS

Progressive replacement of embryo-derived cardiac macrophages with age

(2014) Kaaweh Molawi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Monocytes Infiltrate the Pancreas via the MCP-1/CCR2 Pathway and Differentiate into Stellate Cells

(2014) Kazuko Ino et al.   PLoS One

Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis

(2014) T. DeFalco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7

(2014) Xiangwei Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

The central role of antigen presentation in islets of Langerhans in autoimmune diabetes

(2013) Boris Calderon et al.   CURRENT OPINION IN IMMUNOLOGY

Resident Macrophages Mediate Islet Amyloid Polypeptide–Induced Islet IL-1β Production and β-Cell Dysfunction

(2013) Clara Y. Westwell-Roper et al.   DIABETES

The immune cells in adipose tissue

(2013) A. W. Ferrante   DIABETES OBESITY & METABOLISM

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Liver-resident NK cells confer adaptive immunity in skin-contact inflammation

(2013) Hui Peng et al.   JOURNAL OF CLINICAL INVESTIGATION

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization

(2013) H. Cucak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

(2013) Ansuman T Satpathy et al.   NATURE IMMUNOLOGY

Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing

(2012) Scott W. Boyer et al.   CELL CYCLE

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Zbtb46expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

(2012) Ansuman T. Satpathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

(2012) Matthew M. Meredith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

(2012) Guillaume Hoeffel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Listeriolysin O Is Strongly Immunogenic Independently of Its Cytotoxic Activity

(2012) Javier A. Carrero et al.   PLoS One

An Abundant Tissue Macrophage Population in the Adult Murine Heart with a Distinct Alternatively-Activated Macrophage Profile

(2012) Alexander R. Pinto et al.   PLoS One

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells

(2011) N. Buza-Vidas et al.   BLOOD

All Hematopoietic Cells Develop from Hematopoietic Stem Cells through Flk2/Flt3-Positive Progenitor Cells

(2011) Scott W. Boyer et al.   Cell Stem Cell

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Lymphangiogenesis Is Required for Pancreatic Islet Inflammation and Diabetes

(2011) Na Yin et al.   PLoS One

Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development

(2010) C. Boiers et al.   BLOOD

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

(2010) James F Mohan et al.   NATURE IMMUNOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Islet-associated macrophages in type 2 diabetes

(2009) S. J. Richardson et al.   DIABETOLOGIA

Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation

(2009) Muzlifah Haniffa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Amplification of Autoimmune Response through Induction of Dendritic Cell Maturation in Inflamed Tissues

(2009) K. Melli et al.   JOURNAL OF IMMUNOLOGY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Dendritic cells in islets of Langerhans constitutively present   cell-derived peptides bound to their class II MHC molecules

(2008) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE