Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization

Direct interactions with influenza promote bacterial adherence during respiratory infections

(2019) Hannah M. Rowe et al.   Nature Microbiology

STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation

(2019) Saroj Nepal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus

(2018) Simon P. Jochems et al.   NATURE IMMUNOLOGY

A critical role of Gas6/Axl signal in allergic airway responses during RSV vaccine-enhanced disease

(2017) Takehiko Shibata et al.   IMMUNOLOGY AND CELL BIOLOGY

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

(2017) Alexander V. Misharin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

(2017) Ting Shi et al.   LANCET

Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

(2016) Jihye Han et al.   Autophagy

Respiratory syncytial virus infection activates IL-13–producing group 2 innate lymphoid cells through thymic stromal lymphopoietin

(2016) Matthew T. Stier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Influenza A virus-induced release of interleukin-10 inhibits the anti-microbial activities of invariant natural killer T cells during invasive pneumococcal superinfection

(2016) A Barthelemy et al.   Mucosal Immunology

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

Mechanisms of Interferon-γ Production by Neutrophils and Its Function duringStreptococcus pneumoniaePneumonia

(2015) John C. Gomez et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nasopharyngeal bacterial burden and antibiotics: Influence on inflammatory markers and disease severity in infants with respiratory syncytial virus bronchiolitis

(2015) M. Carmen Suárez-Arrabal et al.   JOURNAL OF INFECTION

Association between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data

(2015) Daniel M. Weinberger et al.   PLOS MEDICINE

RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

(2015) Catherine Ptaschinski et al.   PLoS Pathogens

Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33

(2015) Jordy Saravia et al.   PLoS Pathogens

Respiratory Syncytial Virus Increases the Virulence ofStreptococcus pneumoniaeby Binding to Penicillin Binding Protein 1a. A New Paradigm in Respiratory Infection

(2014) Claire M. Smith et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Growth Arrest–Specific Gene 6 in the Development of Fungal Allergic Airway Disease in Mice

(2014) Takehiko Shibata et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

(2014) J. H. M. van der Meer et al.   BLOOD

Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma

(2014) T. Shibata et al.   JOURNAL OF IMMUNOLOGY

Axl Receptor Blockade Protects from Invasive Pulmonary Aspergillosis in Mice

(2014) Takehiko Shibata et al.   JOURNAL OF IMMUNOLOGY

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae

(2011) Toshinobu Yokoyama et al.   Infection and Drug Resistance

Interferon-γ Production by Neutrophils during Bacterial Pneumonia in Mice

(2010) Mitsuhiro Yamada et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

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Incidence of bacterial coinfection with respiratory syncytial virus bronchopulmonary infection in pediatric inpatients

(2010) Haruka Hishiki et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4- and IFN-β-dependent

(2010) K A Shirey et al.   Mucosal Immunology

Risk Factors in Children Hospitalized With RSV Bronchiolitis Versus Non-RSV Bronchiolitis

(2010) C. G. Garcia et al.   PEDIATRICS

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of the Inflammatory Response toStreptococcus pneumoniaein a Model of Acute Lung Tissue Infection

(2008) Feng Xu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Fusion Protein of Respiratory Syncytial Virus Triggers p53-Dependent Apoptosis

(2008) J. Eckardt-Michel et al.   JOURNAL OF VIROLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE