Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury

Regulated necrosis in kidney ischemia-reperfusion injury

(2019) Aspasia Pefanis et al.   KIDNEY INTERNATIONAL

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation

(2019) Wenjun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

TNFα-Mediated Necroptosis Aggravates Ischemia-Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response

(2019) Faji Yang et al.   Oxidative Medicine and Cellular Longevity

Liver ASK1 protects from non‐alcoholic fatty liver disease and fibrosis

(2019) Tenagne D Challa et al.   EMBO Molecular Medicine

Antibiotic pretreatment alleviates liver transplant damage in mice and humans

(2019) Kojiro Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Heme Oxygenase-1 dictates innate – adaptive immune phenotype in human liver transplantation

(2019) Kentaro Kadono et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Serelaxin induces Notch1 signaling and alleviates hepatocellular damage in orthotopic liver transplantation

(2018) Shoichi Kageyama et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice

(2018) Andrea Kristina Horst et al.   HEPATOLOGY

Recombinant relaxin protects liver transplants from ischemia damage by hepatocyte glucocorticoid receptor: From bench-to-bedside

(2018) Shoichi Kageyama et al.   HEPATOLOGY

Recipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside

(2018) Shoichi Kageyama et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CEACAM1 in Liver Injury, Metabolic and Immune Regulation

(2018) Andrea Horst et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial

(2017) Rohit Loomba et al.   HEPATOLOGY

Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury

(2017) Kojiro Nakamura et al.   JOURNAL OF HEPATOLOGY

Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury

(2017) Shi Yue et al.   JOURNAL OF IMMUNOLOGY

Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human

(2017) Kojiro Nakamura et al.   LIVER TRANSPLANTATION

Negative CD4 + TIM-3 Signaling Confers Resistance Against Cold Preservation Damage in Mouse Liver Transplantation

(2015) Y. Liu et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury

(2015) Yuanxing Liu et al.   JOURNAL OF HEPATOLOGY

Graft rinse prior to reperfusion in liver transplantation: literature review and online survey within the Eurotransplant community

(2015) Philipp Houben et al.   TRANSPLANT INTERNATIONAL

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

(2014) Yu-Hwa Huang et al.   NATURE

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: A role for intracellular high-mobility group box 1 in cellular protection

(2013) Hai Huang et al.   HEPATOLOGY

Cold induces reactive oxygen species production and activation of the NF-kappa B response in endothelial cells and inflammationin vivo

(2013) E. M. Awad et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Soluble thrombomodulin attenuates sinusoidal obstruction syndrome in rat through suppression of high mobility group box 1

(2013) Kojiro Nakamura et al.   LIVER INTERNATIONAL

The Short Isoform of the CEACAM1 Receptor in Intestinal T Cells Regulates Mucosal Immunity and Homeostasis via Tfh Cell Induction

(2012) Lanfen Chen et al.   IMMUNITY

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

(2012) Yuan Zhai et al.   Nature Reviews Gastroenterology & Hepatology

Mechanistic Control of Carcinoembryonic Antigen-related Cell Adhesion Molecule-1 (CEACAM1) Splice Isoforms by the Heterogeneous Nuclear Ribonuclear Proteins hnRNP L, hnRNP A1, and hnRNP M

(2011) Kenneth J. Dery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway

(2010) Xiaoli Guo et al.   EMBO Molecular Medicine

T-Cell Immunoglobulin Mucin-3 Determines Severity of Liver Ischemia/Reperfusion Injury in Mice in a TLR4-Dependent Manner

(2010) Yoichiro Uchida et al.   GASTROENTEROLOGY

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(2008) John Klune et al.   MOLECULAR MEDICINE