Arctiin attenuates high glucose‐induced human retinal capillary endothelial cell proliferation by regulating ROCK1/PTEN/PI3K/Akt/VEGF pathway in vitro

Diabetic Retinopathy: Pathophysiology and Treatments

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Curcumin Alleviates Diabetic Retinopathy in Experimental Diabetic Rats

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Novel Method of Preparation and Activity Research on Arctigenin from Fructus Arctii

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Chlorogenic acid attenuates diabetic retinopathy by reducing VEGF expression and inhibiting VEGF-mediated retinal neoangiogenesis

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Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells

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MiR-126 overexpression inhibits high glucose-induced migration and tube formation of rhesus macaque choroid-retinal endothelial cells by obstructing VEGFA and PIK3R2

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Diabetic retinopathy, an overview

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Association of Repeated Intravitreous Bevacizumab Injections With Risk for Glaucoma Surgery

(2017) Brennan D. Eadie et al.   JAMA Ophthalmology

MiR-20b targets AKT3 and modulates vascular endothelial growth factor-mediated changes in diabetic retinopathy

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Protection of tauroursodeoxycholic acid on high glucose-induced human retinal microvascular endothelial cells dysfunction and streptozotocin-induced diabetic retinopathy rats

(2016) Chun-fei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Circulating Biomarkers of Diabetic Retinopathy: An Overview Based on Physiopathology

(2016) Olga Simó-Servat et al.   Journal of Diabetes Research

Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy

(2015) Ting-Ting Wan et al.   BIOMEDICINE & PHARMACOTHERAPY

Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway

(2015) MINGHONG DENG et al.   Molecular Medicine Reports

Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway

(2015) Wei-Kang Pan et al.   PEDIATRIC BLOOD & CANCER

Diabetic Retinopathy

(2015) Andrew M. Hendrick et al.   PRIMARY CARE

Repeated Intravitreous Ranibizumab Injections for Diabetic Macular Edema and the Risk of Sustained Elevation of Intraocular Pressure or the Need for Ocular Hypotensive Treatment

(2015) Susan B. Bressler et al.   JAMA Ophthalmology

Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture

(2015) Ana Galán-Cobo et al.   PLoS One

Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and Is Associated With Akt Activation and HIF1α-VEGF Pathway Inhibition

(2014) Hu Huang et al.   DIABETES

A review of anti-VEGF agents for proliferative diabetic retinopathy

(2014) P Osaadon et al.   EYE

PTEN/PI3K/Akt/VEGF signaling and the cross talk to KRIT1, CCM2, and PDCD10 proteins in cerebral cavernous malformations

(2014) Souvik Kar et al.   NEUROSURGICAL REVIEW

Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet

(2014) Byulchorong Min et al.   Nutrition Research and Practice

Potassium channels in cell cycle and cell proliferation

(2014) D. Urrego et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Optimization of Extraction and Purification of Arctiin from Fructus arctii and Its Protection Against Glucose-Induced Rat Aortic Endothelial Cell Injury

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Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity

(2012) Aparna Pal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Arctiin on Streptozotocin-Induced Diabetic Retinopathy in Sprague-Dawley Rats

(2012) Lai-chun Lu et al.   PLANTA MEDICA

PI(3)K/PTEN/AKT pathway

(2010) Anne-Christine Piguet et al.   JOURNAL OF HEPATOLOGY

High glucose attenuates insulin-induced VEGF expression in bovine retinal microvascular endothelial cells

(2009) H Wu et al.   EYE

In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway

(2009) Feng Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

PTEN regulate angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells

(2009) Jiachi Ma et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The role of PTEN signaling perturbations in cancer and in targeted therapy

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