Single-cell multiomic analysis of in vivo and in vitro matured human oocytes

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

DNA methylation and mRNA expression of imprinted genes in blastocysts derived from an improved in vitro maturation method for oocytes from small antral follicles in polycystic ovary syndrome patients

(2019) M D Saenz-de-Juano et al.   HUMAN REPRODUCTION

Chromosome errors in human eggs shape natural fertility over reproductive life span

(2019) Jennifer R. Gruhn et al.   SCIENCE

Single-Cell Transcriptomics of Human Oocytes: Environment-Driven Metabolic Competition and Compensatory Mechanisms During Oocyte Maturation

(2018) Hongcui Zhao et al.   ANTIOXIDANTS & REDOX SIGNALING

Comprehensive meta-analysis reveals association between multiple imprinting disorders and conception by assisted reproductive technology

(2018) Victoria K. Cortessis et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell multi-omics sequencing of human early embryos

(2018) Lin Li et al.   NATURE CELL BIOLOGY

Minor zygotic gene activation is essential for mouse preimplantation development

(2018) Ken-ichiro Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human oocyte maturation in vitro is improved by co-culture with cumulus cells from mature oocytes

(2018) Irma Virant-Klun et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Single-cell multiomics sequencing and analyses of human colorectal cancer

(2018) Shuhui Bian et al.   SCIENCE

Development of in vitro maturation techniques for clinical applications

(2017) Zhi-Yong Yang et al.   FERTILITY AND STERILITY

Single-cell DNA methylome sequencing of human preimplantation embryos

(2017) Ping Zhu et al.   NATURE GENETICS

Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation

(2017) Bo Yu et al.   Stem Cell Reports

Single-cell triple omics sequencing reveals genetic, epigenetic and transcriptomic heterogeneity in hepatocellular carcinomas

(2016) Yu Hou et al.   CELL RESEARCH

Single-cell analysis of differences in transcriptomic profiles of oocytes and cumulus cells at GV, MI, MII stages from PCOS patients

(2016) Qiwei Liu et al.   Scientific Reports

Maternal PCBP1 determines the normal timing of pronucleus formation in mouse eggs

(2015) Zhonghua Shi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Comparison of genome-wide and gene-specific DNA methylation between ART and naturally conceived pregnancies

(2015) Nir Melamed et al.   Epigenetics

mRNA Levels of Imprinted Genes in Bovine In Vivo Oocytes, Embryos and Cross Species Comparisons with Humans, Mice and Pigs

(2015) Zongliang Jiang et al.   Scientific Reports

DNA methylation differences between in vitro- and in vivo-conceived children are associated with ART procedures rather than infertility

(2015) Sisi Song et al.   Clinical Epigenetics

Human in vitro oocyte maturation is not associated with increased imprinting error rates at LIT1, SNRPN, PEG3 and GTL2

(2014) J. Kuhtz et al.   HUMAN REPRODUCTION

The DNA methylation landscape of human early embryos

(2014) Hongshan Guo et al.   NATURE

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity

(2014) Sébastien A Smallwood et al.   NATURE METHODS

Abnormal DNA Methylation of Imprinted Loci in Human Preimplantation Embryos

(2014) Xiaoyun Shi et al.   Reproductive Sciences

Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development

(2014) Hiroaki Okae et al.   PLoS Genetics

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

(2013) Jason M. Franasiak et al.   FERTILITY AND STERILITY

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PCBP1 is required for maintenance of the transcriptionally silent state in fully grown mouse oocytes

(2012) Meng Xia et al.   CELL CYCLE

Aberrant DNA methylation of imprinted loci in human in vitro matured oocytes after long agonist stimulation

(2012) Xiaoyun Shi et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Contribution of Intragenic DNA Methylation in Mouse Gametic DNA Methylomes to Establish Oocyte-Specific Heritable Marks

(2012) Hisato Kobayashi et al.   PLoS Genetics

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Deletion of the paternal allele of the imprinted MEST/PEG1 region in a patient with Silver-Russell syndrome features

(2011) T Eggermann et al.   CLINICAL GENETICS

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

(2011) Michael J. Ziller et al.   PLoS Genetics

Dynamic changes in the human methylome during differentiation

(2010) L. Laurent et al.   GENOME RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Beckwith–Wiedemann syndrome

(2009) Rosanna Weksberg et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Gene expression profiling of human oocytes at different maturational stages and after in vitro maturation

(2008) Dagan Wells et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos

(2008) Pengpeng Ma et al.   DEVELOPMENTAL BIOLOGY