Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases
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Title
Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases
Authors
Keywords
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Journal
HUMAN GENETICS
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-31
DOI
10.1007/s00439-020-02154-2
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Note: Only part of the references are listed.- Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification
- (2020) Aziz Bousfiha et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci
- (2019) Tom Dudding et al. Nature Communications
- Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
- (2019) Yi Rang Na et al. Nature Reviews Gastroenterology & Hepatology
- Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target
- (2019) Nuphar Veiga et al. JOURNAL OF CONTROLLED RELEASE
- Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells
- (2018) S. Alivernini et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation
- (2018) Venetia Bigley et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Sensing of invading pathogens by GBPs: At the crossroads between cell-autonomous and innate immunity
- (2018) José Carlos Santos et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis
- (2018) Fengna Chu et al. JOURNAL OF NEUROIMMUNOLOGY
- Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
- (2018) Xiao-Fei Kong et al. NATURE IMMUNOLOGY
- Cerebral Malaria in Mouse and Man
- (2018) Nazanin Ghazanfari et al. Frontiers in Immunology
- Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells
- (2018) Stéphanie Humblet-Baron et al. BLOOD
- Genome-wide association studies identifyPRKCBas a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population
- (2017) Minae Kawashima et al. HUMAN MOLECULAR GENETICS
- Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility
- (2017) Masaki Takeuchi et al. NATURE GENETICS
- IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection
- (2017) Rajesh M. Valanparambil et al. PLoS Pathogens
- The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
- (2016) William J. Astle et al. CELL
- Interferon regulatory factor 8 and the regulation of neutrophil, monocyte, and dendritic cell production
- (2016) Alberto Yáñez et al. CURRENT OPINION IN HEMATOLOGY
- Biallelic mutations in IRF8 impair human NK cell maturation and function
- (2016) Emily M. Mace et al. JOURNAL OF CLINICAL INVESTIGATION
- The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation
- (2016) David Langlais et al. JOURNAL OF EXPERIMENTAL MEDICINE
- USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation
- (2016) Sabrina Torre et al. NATURE IMMUNOLOGY
- Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection
- (2016) Nassima Fodil et al. TRENDS IN IMMUNOLOGY
- A dualcis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
- (2015) Alessandra Mancino et al. GENES & DEVELOPMENT
- Regulation of myelopoiesis by the transcription factor IRF8
- (2015) Tomohiko Tamura et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
- (2015) Hong Liu et al. NATURE GENETICS
- Pathogenic CD8+ T cells in experimental cerebral malaria
- (2015) Shanshan Wu Howland et al. Seminars in Immunopathology
- Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis
- (2015) Maria Arismendi et al. ARTHRITIS RESEARCH & THERAPY
- International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
- (2015) Heather J. Cordell et al. Nature Communications
- Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8K108E mutation
- (2014) S. Salem et al. BLOOD
- Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1
- (2014) Ynto S. de Boer et al. GASTROENTEROLOGY
- The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation
- (2014) Yuko Yoshida et al. IMMUNITY
- CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation
- (2014) James M. Kennedy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation
- (2014) Xianqin Zhang et al. NATURE
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Coronary Heart Disease in Systemic Lupus Erythematosus Is Associated With Interferon Regulatory Factor-8 Gene Variants
- (2013) Dag Leonard et al. Circulation-Cardiovascular Genetics
- Genetic variation associated with circulating monocyte count in the eMERGE Network
- (2013) David R. Crosslin et al. HUMAN MOLECULAR GENETICS
- Single-nucleotide polymorphisms ofIRF8gene are associated with systemic lupus erythematosus in Chinese Han population
- (2013) S.-W. Li et al. International Journal of Immunogenetics
- Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer
- (2013) Xiaolin Hu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood
- (2013) Minji Byun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
- (2013) Ashley H Beecham et al. NATURE GENETICS
- Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria
- (2013) Joanne Berghout et al. PLoS Pathogens
- BATF–JUN is critical for IRF4-mediated transcription in T cells
- (2012) Peng Li et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes
- (2012) E. Glasmacher et al. SCIENCE
- Mycobacterial Disease and Impaired IFN- Immunity in Humans with Inherited ISG15 Deficiency
- (2012) D. Bogunovic et al. SCIENCE
- Dissecting the Genetics of Complex Inheritance: Linkage Disequilibrium Mapping Provides Insight into Crohn Disease
- (2011) Heather Elding et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- (2011) Stephen Sawcer et al. NATURE
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- IRF8Mutations and Human Dendritic-Cell Immunodeficiency
- (2011) Sophie Hambleton et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Genetic Association of Variants in CD6, TNFRSF1A and IRF8 to Multiple Sclerosis: A Multicenter Case-Control Study
- (2011) PLoS One
- Removal of GABAA Receptor γ2 Subunits from Parvalbumin Neurons Causes Wide-Ranging Behavioral Alterations
- (2011) Elli Leppä et al. PLoS One
- Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy
- (2011) Olga Gorlova et al. PLoS Genetics
- Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis
- (2011) Jean-François Marquis et al. PLoS Genetics
- Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
- (2011) Deborah S. Cunninghame Graham et al. PLoS Genetics
- Restriction of Legionella pneumophila Replication in Macrophages Requires Concerted Action of the Transcriptional Regulators Irf1 and Irf8 and Nod-Like Receptors Naip5 and Nlrc4
- (2009) A. Fortier et al. INFECTION AND IMMUNITY
- Disseminated and Rapidly Fatal Tuberculosis in Mice Bearing a Defective Allele at IFN Regulatory Factor 8
- (2009) J.-F. Marquis et al. JOURNAL OF IMMUNOLOGY
- A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
- (2009) Vesela Gateva et al. NATURE GENETICS
- Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
- (2009) Philip L De Jager et al. NATURE GENETICS
- Genetic and genomic analyses of host-pathogen interactions in malaria
- (2009) Silayuv E. Bongfen et al. TRENDS IN PARASITOLOGY
- The IRF Family Transcription Factors in Immunity and Oncogenesis
- (2008) Tomohiko Tamura et al. Annual Review of Immunology
- The Interferon Consensus Sequence-binding Protein (ICSBP/IRF8) RepressesPTPN13Gene Transcription in Differentiating Myeloid Cells
- (2008) Weiqi Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Pyruvate Kinase Deficiency and Malaria
- (2008) Kodjo Ayi et al. NEW ENGLAND JOURNAL OF MEDICINE
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