Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer
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Title
Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 288, Issue 26, Pages 19103-19115
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2013-05-16
DOI
10.1074/jbc.m112.434530
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Note: Only part of the references are listed.- Oxidative Stress Regulates Expression of VEGFR1 in Myeloid Cells: Link to Tumor-Induced Immune Suppression in Renal Cell Carcinoma
- (2014) S. Kusmartsev et al. JOURNAL OF IMMUNOLOGY
- Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells
- (2014) P. Sinha et al. JOURNAL OF IMMUNOLOGY
- Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
- (2013) T. A. Mace et al. CANCER RESEARCH
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- (2013) I. R. Ramachandran et al. JOURNAL OF IMMUNOLOGY
- Myeloid suppressor cells and immune modulation in lung cancer
- (2012) Minu K Srivastava et al. Immunotherapy
- Decitabine and Vorinostat Cooperate To Sensitize Colon Carcinoma Cells to Fas Ligand-Induced Apoptosis In Vitro and Tumor Suppression In Vivo
- (2012) D. Yang et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Mast Cells Critically Augment Myeloid-Derived Suppressor Cell Activity
- (2012) S. J. Saleem et al. JOURNAL OF IMMUNOLOGY
- NK Cell Response to Vaccinia Virus Is Regulated by Myeloid-Derived Suppressor Cells
- (2012) C. Fortin et al. JOURNAL OF IMMUNOLOGY
- Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release
- (2012) P. Jayaraman et al. JOURNAL OF IMMUNOLOGY
- Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer
- (2012) Minu K. Srivastava et al. PLoS One
- Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B
- (2012) R W Rooswinkel et al. Cell Death & Disease
- Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL
- (2011) P. Sinha et al. BLOOD
- Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
- (2011) N. Obermajer et al. BLOOD
- A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells
- (2011) S. Solito et al. BLOOD
- IRF8 Regulates Acid Ceramidase Expression to Mediate Apoptosis and Suppresses Myelogeneous Leukemia
- (2011) X. Hu et al. CANCER RESEARCH
- Verticillin A Overcomes Apoptosis Resistance in Human Colon Carcinoma through DNA Methylation-Dependent Upregulation of BNIP3
- (2011) F. Liu et al. CANCER RESEARCH
- Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice
- (2011) B. L. Mundy-Bosse et al. CANCER RESEARCH
- Regulation of CD95/Fas signaling at the DISC
- (2011) I N Lavrik et al. CELL DEATH AND DIFFERENTIATION
- High Cell Surface Death Receptor Expression Determines Type IVersusType II Signaling
- (2011) Xue Wei Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8
- (2011) Aminah Ikner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modeling Reveals That Dynamic Regulation of c-FLIP Levels Determines Cell-to-Cell Distribution of CD95-mediated Apoptosis
- (2011) Hannu T. Toivonen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells
- (2011) J. Yang et al. JOURNAL OF IMMUNOLOGY
- IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival
- (2011) H. R. Turnquist et al. JOURNAL OF IMMUNOLOGY
- Myeloid-Specific Expression of Human Lysosomal Acid Lipase Corrects Malformation and Malfunction of Myeloid-Derived Suppressor Cells in lal-/- Mice
- (2011) P. Qu et al. JOURNAL OF IMMUNOLOGY
- Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
- (2011) S. Ryzhov et al. JOURNAL OF IMMUNOLOGY
- Murine Pancreatic Adenocarcinoma Dampens SHIP-1 Expression and Alters MDSC Homeostasis and Function
- (2011) Shari Pilon-Thomas et al. PLoS One
- Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development
- (2011) Michio Yamamoto et al. PLoS One
- Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism
- (2011) Jeremy D. Waight et al. PLoS One
- Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation
- (2011) A M M Kober et al. Cell Death & Disease
- Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein
- (2010) N. P. Nikolov et al. BLOOD
- Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity
- (2010) Suzanne Ostrand-Rosenberg CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2010) S. Nagaraj et al. CLINICAL CANCER RESEARCH
- ALPS—Ten Lessons from an International Workshop on a Genetic Disease of Apoptosis
- (2010) Michael J. Lenardo et al. IMMUNITY
- Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells
- (2010) Trina J. Stewart et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
- (2010) Cesar A. Corzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17 Promotes Tumor Development through the Induction of Tumor Promoting Microenvironments at Tumor Sites and Myeloid-Derived Suppressor Cells
- (2010) Donggou He et al. JOURNAL OF IMMUNOLOGY
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- (2010) L. A. Haile et al. JOURNAL OF IMMUNOLOGY
- Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells
- (2010) M. G. Lechner et al. JOURNAL OF IMMUNOLOGY
- Loss of Irf8 does not co-operate with overexpression of BCL-2 in the induction of leukemias in vivo
- (2010) Jessica Koenigsmann et al. LEUKEMIA & LYMPHOMA
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- (2010) Thomas Condamine et al. TRENDS IN IMMUNOLOGY
- Role of apoptosis resistance in immune evasion and metastasis of colorectal cancer
- (2010) Kebin Liu World Journal of Gastrointestinal Oncology
- IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor-Initiated Apoptosis via Repression of FLICE-like Protein Expression
- (2009) D. Yang et al. CANCER RESEARCH
- The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies
- (2009) J. Ozao-Choy et al. CANCER RESEARCH
- Modulating the Expression of IFN Regulatory Factor 8 Alters the Protumorigenic Behavior of CD11b+Gr-1+ Myeloid Cells
- (2009) T. J. Stewart et al. JOURNAL OF IMMUNOLOGY
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- (2009) M. O. Kilinc et al. JOURNAL OF IMMUNOLOGY
- Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
- (2009) S. Ostrand-Rosenberg et al. JOURNAL OF IMMUNOLOGY
- Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis
- (2008) Li Yang et al. CANCER CELL
- CD95 Stimulation Results in the Formation of a Novel Death Effector Domain Protein-containing Complex
- (2008) Inna N. Lavrik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
- (2008) Pingyan Cheng et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
- (2008) Avi Ashkenazi NATURE REVIEWS DRUG DISCOVERY
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