The human genetic determinism of life-threatening infectious diseases: genetic heterogeneity and physiological homogeneity?

Mendelian susceptibility to mycobacterial disease: recent discoveries

(2020) Jacinta Bustamante   HUMAN GENETICS

Human genetics of HCV infection phenotypes in the era of direct-acting antivirals

(2020) Pierre Nahon et al.   HUMAN GENETICS

The genetic basis of pneumococcal and staphylococcal infections: inborn errors of human TLR and IL-1R immunity

(2020) Bertrand Boisson   HUMAN GENETICS

New approaches to the study of immune responses in humans

(2020) Petter Brodin   HUMAN GENETICS

Herpes simplex virus encephalitis of childhood: inborn errors of central nervous system cell-intrinsic immunity

(2020) Shen-Ying Zhang   HUMAN GENETICS

Susceptibility to infection in early life: a growing role for human genetics

(2020) Alessandro Borghesi et al.   HUMAN GENETICS

Genetic determinants of host immunity against human rhinovirus infections

(2020) Ian T. Lamborn et al.   HUMAN GENETICS

Human genetics of life-threatening influenza pneumonitis

(2020) Qian Zhang   HUMAN GENETICS

Human genetics of leishmania infections

(2020) Jenefer M. Blackwell et al.   HUMAN GENETICS

The monogenic basis of human tuberculosis

(2020) Stephanie Boisson-Dupuis   HUMAN GENETICS

Human genetics and malaria resistance

(2020) Silvia N. Kariuki et al.   HUMAN GENETICS

Human genetics of meningococcal infections

(2020) Stephanie Hodeib et al.   HUMAN GENETICS

Incomplete penetrance in primary immunodeficiency: a skeleton in the closet

(2020) Conor Gruber et al.   HUMAN GENETICS

Human inborn errors of immunity underlying superficial or invasive candidiasis

(2020) Anne Puel   HUMAN GENETICS

Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

(2020) Stuart G. Tangye et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency

(2020) Scott B. Drutman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lethal Infectious Diseases as Inborn Errors of Immunity: Toward a Synthesis of the Germ and Genetic Theories

(2020) Jean-Laurent Casanova et al.   Annual Review of Pathology-Mechanisms of Disease

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection

(2020) Jean-Laurent Casanova et al.   CELL

Human genetics of Buruli ulcer

(2020) Jeremy Manry   HUMAN GENETICS

Evolutionary and population (epi)genetics of immunity to infection

(2020) Luis B. Barreiro et al.   HUMAN GENETICS

Identifying disease-causing mutations in genomes of single patients by computational approaches

(2020) Cigdem Sevim Bayrak et al.   HUMAN GENETICS

Human genetic dissection of papillomavirus-driven diseases: new insight into their pathogenesis

(2020) Vivien Béziat   HUMAN GENETICS

Minding the gap in HIV host genetics: opportunities and challenges

(2020) Shanelle N. Gingras et al.   HUMAN GENETICS

Human genetic basis of fulminant viral hepatitis

(2020) Emmanuelle Jouanguy   HUMAN GENETICS

Genetic susceptibility to EBV infection: insights from inborn errors of immunity

(2020) Stuart G. Tangye   HUMAN GENETICS

Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes

(2020) Hélia Dessein et al.   HUMAN GENETICS

Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases

(2020) Sandra Salem et al.   HUMAN GENETICS

Autoantibodies against cytokines: phenocopies of primary immunodeficiencies?

(2020) Chen-Lung Ku et al.   HUMAN GENETICS

Human Immunology through the Lens of Evolutionary Genetics

(2019) Lluis Quintana-Murci   CELL

Homozygosity for TYK2 P1104A underlies tuberculosis in about 1% of patients in a cohort of European ancestry

(2019) Gaspard Kerner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe influenza pneumonitis in children with inherited TLR3 deficiency

(2019) Hye Kyung Lim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modeling Varicella Zoster Virus Persistence and Reactivation – Closer to Resolving a Perplexing Persistent State

(2019) Lillian Laemmle et al.   Frontiers in Microbiology

Human inborn errors of immunity to infection affecting cells other than leukocytes: from the immune system to the whole organism

(2019) Shen-Ying Zhang et al.   CURRENT OPINION IN IMMUNOLOGY

Fondness for sugars of enteric viruses confronts them with human glycans genetic diversity

(2019) Jacques Le Pendu et al.   HUMAN GENETICS

Mx genes: host determinants controlling influenza virus infection and trans-species transmission

(2019) Otto Haller et al.   HUMAN GENETICS

Exploring the interactions between the human and viral genomes

(2019) Jacques Fellay et al.   HUMAN GENETICS

Genetics of leprosy: today and beyond

(2019) Vinicius M. Fava et al.   HUMAN GENETICS

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

(2019) Michael J. Mina et al.   SCIENCE

Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β

(2019) Juan Li et al.   Science Immunology

Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles

(2019) Velislava N. Petrova et al.   Science Immunology

Regulatory genome variants in human susceptibility to infection

(2019) Amalio Telenti et al.   HUMAN GENETICS

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis

(2019) Fabien G. Lafaille et al.   NATURE MEDICINE

Human genetics of infectious diseases: Unique insights into immunological redundancy

(2018) Jean-Laurent Casanova et al.   SEMINARS IN IMMUNOLOGY

IRF4 haploinsufficiency in a family with Whipple’s disease

(2018) Antoine Guérin et al.   eLife

Influenza

(2018) Florian Krammer et al.   Nature Reviews Disease Primers

Mendelian susceptibility to mycobacterial disease: 2014-2018 update

(2018) Jérémie Rosain et al.   IMMUNOLOGY AND CELL BIOLOGY

Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection

(2018) Bastian Zimmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The phylogenomics of evolving virus virulence

(2018) Jemma L. Geoghegan et al.   NATURE REVIEWS GENETICS

Risk Factors in Children Older Than 5 Years With Pneumococcal Meningitis

(2017) Fanny Hénaff et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Heterogeneities in the case fatality ratio in the West African Ebola outbreak 2013–2016

(2017) Tini Garske et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pathogenesis ofStaphylococcus aureusBloodstream Infections

(2016) Lena Thomer et al.   Annual Review of Pathology-Mechanisms of Disease

Emerging bacterial pathogens: the past and beyond

(2016) M. Vouga et al.   CLINICAL MICROBIOLOGY AND INFECTION

Host genetics of severe influenza: from mouse Mx1 to human IRF7

(2016) Michael J Ciancanelli et al.   CURRENT OPINION IN IMMUNOLOGY

Exome and genome sequencing for inborn errors of immunity

(2016) Isabelle Meyts et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intracellular innate immune surveillance devices in plants and animals

(2016) J. D. G. Jones et al.   SCIENCE

Tuberculosis in Newborns: The Lessons of the “Lübeck Disaster” (1929–1933)

(2016) Gregory J. Fox et al.   PLoS Pathogens

The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

(2015) John C. Kash et al.   AMERICAN JOURNAL OF PATHOLOGY

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults

(2015) Himal Lal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human genetic basis of interindividual variability in the course of infection

(2015) Jean-Laurent Casanova   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe infectious diseases of childhood as monogenic inborn errors of immunity

(2015) Jean-Laurent Casanova   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

(2014) Jacinta Bustamante et al.   SEMINARS IN IMMUNOLOGY

The Genetic Theory of Infectious Diseases: A Brief History and Selected Illustrations

(2013) Jean-Laurent Casanova et al.   Annual Review of Genomics and Human Genetics

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood

(2013) Minji Byun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evolutionary implications of a third lymphocyte lineage in lampreys

(2013) Masayuki Hirano et al.   NATURE

Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis

(2012) Anne Puel et al.   Current Opinion in Allergy and Clinical Immunology

Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans

(2012) Horst von Bernuth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

(2012) Fabien G. Lafaille et al.   NATURE

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Infectious Complications Associated with Immunomodulating Biologic Agents

(2011) Sophia Koo et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Genes controlling vaccine responses and disease resistance to respiratory viral pathogens in cattle

(2011) Elizabeth J. Glass et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Life-threatening infectious diseases of childhood: single-gene inborn errors of immunity?

(2010) Alexandre Alcaïs et al.   Annals of the New York Academy of Sciences

Treatment of Disseminated Mycobacterial Infection with High-Dose IFN-γin a Patient with IL-12Rβ1 Deficiency

(2010) Abdullah A. Alangari et al.   Clinical & Developmental Immunology

A Life of Adventure in Immunobiology

(2009) Max D. Cooper   Annual Review of Immunology

Genetic control of resistance to human malaria

(2009) Anthony C Allison   CURRENT OPINION IN IMMUNOLOGY

Dual nature of the adaptive immune system in lampreys

(2009) Peng Guo et al.   NATURE

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Mycobacterial and Other Serious Infections in Patients Receiving Anti–Tumor Necrosis Factor and Other Newly Approved Biologic Therapies: Case Finding through the Emerging Infections Network

(2008) Kevin L. Winthrop et al.   CLINICAL INFECTIOUS DISEASES

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Forward Genetic Dissection of Immunity to Infection in the Mouse

(2007) S.M. Vidal et al.   Annual Review of Immunology