Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis

DOCK8 deficiency

(2012) Helen C. Su et al.   Annals of the New York Academy of Sciences

The phenotype of human STK4 deficiency

(2012) H. Abdollahpour et al.   BLOOD

Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain

(2012) S. Takezaki et al.   JOURNAL OF IMMUNOLOGY

Herpes in STAT1 gain-of-function mutation

(2012) Beáta Tóth et al.   LANCET

Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or I B  Deficiency

(2011) C. Picard et al.   CLINICAL MICROBIOLOGY REVIEWS

Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: Clinical and pathogenetic implications

(2011) Kai Kisand et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells

(2011) Neil V. Morgan et al.   JOURNAL OF CLINICAL INVESTIGATION

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-27-Mediated Suppression of Human Th17 Cells Is Associated with Activation of STAT1 and Suppressor of Cytokine Signaling Protein 1

(2011) Hong Liu et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Insights into human antifungal immunity from primary immunodeficiencies

(2011) Donald C Vinh   LANCET INFECTIOUS DISEASES

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Sanne P. Smeekens et al.   PLoS One

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Successful Treatment of Chronic Mucocutaneous Candidiasis Caused by Azole-ResistantCandida albicanswith Posaconazole

(2010) Davide Firinu et al.   Clinical & Developmental Immunology

Immunodeficiency due to mutations in ORAI1 and STIM1

(2010) Stefan Feske et al.   CLINICAL IMMUNOLOGY

Superficial mycoses in immunodepressed patients (AIDS)

(2010) Marcia Ramos-e-Silva et al.   CLINICS IN DERMATOLOGY

Dedicator of cytokinesis 8 (DOCK8) deficiency

(2010) Helen C Su   Current Opinion in Allergy and Clinical Immunology

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

(2010) Kiyoshi Hirahara et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

(2010) Rebecca A. Drummond et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-27 Induces a STAT1/3- and NF-κB-dependent Proinflammatory Cytokine Profile in Human Monocytes

(2010) Christina Guzzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT1-Activating Cytokines Limit Th17 Responses through Both T-bet-Dependent and -Independent Mechanisms

(2010) A. V. Villarino et al.   JOURNAL OF IMMUNOLOGY

Revisiting Human IL-12Rβ1 Deficiency

(2010) Ludovic de Beaucoudrey et al.   MEDICINE

Autosomal dominant chronic mucocutaneous candidiasis and primary hypothyroidism complicated by oesophageal carcinoma

(2009) D. Koch et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

(2009) M. Hong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Hyper-IgE syndrome

(2009) Yoshiyuki Minegishi   CURRENT OPINION IN IMMUNOLOGY

Regulatory effects of IFN-β on production of osteopontin and IL-17 by CD4+ T Cells in MS

(2009) Meiyue Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human genetics of infectious diseases: between proof of principle and paradigm

(2009) Alexandre Alcaïs et al.   JOURNAL OF CLINICAL INVESTIGATION

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rethinking T cell immunity in oropharyngeal candidiasis: Figure 1.

(2009) Liise-anne Pirofski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFN-  Inhibits Human Th17 Cell Differentiation

(2009) V. S. Ramgolam et al.   JOURNAL OF IMMUNOLOGY

Differential Effect of IL-27 on Developing versus Committed Th17 Cells

(2009) M. El-behi et al.   JOURNAL OF IMMUNOLOGY

The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling

(2009) S. Crabe et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I

(2009) E. S. Husebye et al.   JOURNAL OF INTERNAL MEDICINE

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combined Immunodeficiency Associated withDOCK8Mutations

(2009) Qian Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED

(2008) K. R. Ryan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Hyper IgE syndrome: an update on clinical aspects and the role of signal transducer and activator of transcription 3

(2008) Michelle L Paulson et al.   Current Opinion in Allergy and Clinical Immunology

Exogenous IFN-γ ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells

(2008) Gang Feng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Patients with Chronic Mucocutaneous Candidiasis Exhibit Reduced Production of Th17-Associated Cytokines IL-17 and IL-22

(2008) Kilian Eyerich et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Chronic mucocutaneous candidiasis and oesophageal cancer

(2008) Daniela D. Rosa et al.   MEDICAL MYCOLOGY

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology