Structural and functional divergence of GDAP1 from the glutathione S‐transferase superfamily

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A role for the GDAP1 gene in the molecular pathogenesis of Charcot-Marie-Tooth disease

(2018) Weronika Rzepnikowska et al.   ACTA NEUROBIOLOGIAE EXPERIMENTALIS

Genotype–phenotype correlation and frequency of distribution in a cohort of Chinese Charcot–Marie–Tooth patients associated with GDAP1 mutations

(2018) Pukar Singh Pakhrin et al.   JOURNAL OF NEUROLOGY

A novel mutation in the FGD4 gene causing Charcot-Marie-Tooth disease

(2017) Panagiotis Zis et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration

(2017) Paloma González-Sánchez et al.   Scientific Reports

Oxidative stress and lipotoxicity

(2016) Amy K. Hauck et al.   JOURNAL OF LIPID RESEARCH

Plasma neurofilament heavy chain is not a useful biomarker in Charcot-Marie-Tooth disease

(2016) Alexander M. Rossor et al.   MUSCLE & NERVE

Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

(2016) Nina Huber et al.   Scientific Reports

Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin

(2015) Kate E. Helmich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Template-based protein structure prediction in CASP11 and retrospect of I-TASSER in the last decade

(2015) Jianyi Yang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy

(2015) Manuela Barneo-Muñoz et al.   PLoS Genetics

The Gdap1 knockout mouse mechanistically links redox control to Charcot–Marie–Tooth disease

(2014) Axel Niemann et al.   BRAIN

Charcot Marie Tooth disease (CMT): historical perspectives and evolution

(2014) Mohamed Kazamel et al.   JOURNAL OF NEUROLOGY

Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter

(2013) Ira Kukic et al.   BIOCHEMICAL JOURNAL

Loss of TRPML1 promotes production of reactive oxygen species: is oxidative damage a factor in mucolipidosis type IV?

(2013) Jessica Coblentz et al.   BIOCHEMICAL JOURNAL

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission

(2013) Nina Huber et al.   EMBO REPORTS

Clinical implications of genetic advances in Charcot–Marie–Tooth disease

(2013) Alexander M. Rossor et al.   Nature Reviews Neurology

Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry

(2013) David Pla-Martín et al.   NEUROBIOLOGY OF DISEASE

Charcot-Marie-Tooth disease: Genetic and clinical spectrum in a Spanish clinical series

(2013) R. Sivera et al.   NEUROLOGY

Charcot–Marie–Tooth disease: frequency of genetic subtypes and guidelines for genetic testing

(2012) Sinead M Murphy et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The combined use of photoaffinity labeling and surface plasmon resonance-based technology identifies multiple salicylic acid-binding proteins

(2012) Miaoying Tian et al.   PLANT JOURNAL

Neural and Molecular Features on Charcot-Marie-Tooth Disease Plasticity and Therapy

(2012) Paula Juárez et al.   NEURAL PLASTICITY

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Glutathione transferases: a structural perspective

(2011) Aaron Oakley   DRUG METABOLISM REVIEWS

Rapid force generation is impaired in cerebral palsy and is related to decreased muscle size and functional mobility

(2011) Noelle G. Moreau et al.   GAIT & POSTURE

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential

(2011) Rebecca Noack et al.   HUMAN MOLECULAR GENETICS

Charcot-Marie-Tooth-related GeneGDAP1Complements Cell Cycle Delay at G2/M Phase inSaccharomyces cerevisiae fis1Gene-defective Cells

(2011) Anna Estela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mitochondrial dysfunction and pathophysiology of Charcot–Marie–Tooth disease involving GDAP1 mutations

(2010) Julien Cassereau et al.   EXPERIMENTAL NEUROLOGY

Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V

(2010) Indalecio Quesada-Soriano et al.   JOURNAL OF MOLECULAR RECOGNITION

Phenotypical features of the p.R120W mutation in the GDAP1 gene causing autosomal dominant Charcot-Marie-Tooth disease

(2010) Rafael Sivera et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance

(2009) Axel Niemann et al.   NEUROBIOLOGY OF DISEASE

Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor

(2009) Konstanze M. Wagner et al.   PLoS One

Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: Structure-thermodynamic relationships and thermal stability

(2009) Indalecio Quesada-Soriano et al.   PROTEIN SCIENCE

Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease

(2008) Laia Pedrola et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE