Copper promotion of myocardial regeneration

Profiling of nuclear copper-binding proteins under hypoxic condition

(2019) Haiying Fu et al.   BIOMETALS

Phosphatase PPM1L Prevents Excessive Inflammatory Responses and Cardiac Dysfunction after Myocardial Infarction by Inhibiting IKKβ Activation

(2019) Bo Wang et al.   JOURNAL OF IMMUNOLOGY

Cardiac regeneration using human‐induced pluripotent stem cell‐derived biomaterial‐free 3D‐bioprinted cardiac patch in vivo

(2019) Enoch Yeung et al.   Journal of Tissue Engineering and Regenerative Medicine

An acute immune response underlies the benefit of cardiac stem-cell therapy

(2019) Ronald J. Vagnozzi et al.   NATURE

Copper Metal–Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes

(2018) Jisheng Xiao et al.   ACS Nano

Copper Transporters and Copper Chaperones: Roles in Cardiovascular Physiology and Disease.

(2018) Tohru Fukai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Featured Article: The loss of copper is associated with the increase in copper metabolism MURR domain 1 in ischemic hearts of mice

(2018) Kui Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Copper-induced reduction in myocardial fibrosis is associated with increased matrix metalloproteins in a rat model of cardiac hypertrophy

(2018) Yinjie Liu et al.   Metallomics

Exercise preconditioning and low dose copper nanoparticles exhibits cardioprotection through targeting GSK-3β phosphorylation in ischemia/reperfusion induced myocardial infarction

(2018) Arun K. Sharma et al.   MICROVASCULAR RESEARCH

Copper levels affect targeting of hypoxia-inducible factor 1α to the promoters of hypoxia-regulated genes

(2018) Xiaojuan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elesclomol restores mitochondrial function in genetic models of copper deficiency

(2018) Shivatheja Soma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feature Article: Trientine selectively delivers copper to the heart and suppresses pressure overload-induced cardiac hypertrophy in rats

(2018) Jiaming Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regeneration-associated cells improve recovery from myocardial infarction through enhanced vasculogenesis, anti-inflammation, and cardiomyogenesis

(2018) Amankeldi A. Salybekov et al.   PLoS One

Cardiomyocyte renewal in the human heart: insights from the fall-out

(2017) Enikő Lázár et al.   EUROPEAN HEART JOURNAL

Hippo pathway deficiency reverses systolic heart failure after infarction

(2017) John P. Leach et al.   NATURE

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics

(2017) Thomas J. Cahill et al.   NATURE REVIEWS DRUG DISCOVERY

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB

(2017) Si-yong Gao et al.   PLoS One

Dynamics of angiogenesis in ischemic areas of the infarcted heart

(2017) Koichi Kobayashi et al.   Scientific Reports

Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration

(2016) Virpi Talman et al.   CELL AND TISSUE RESEARCH

The association of depressed angiogenic factors with reduced capillary density in the Rhesus monkey model of myocardial ischemia

(2016) Wenjing Zhang et al.   Metallomics

Pharmacological activity of metal binding agents that alter copper bioavailability

(2015) Marian E. Helsel et al.   DALTON TRANSACTIONS

SCFJFKis a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer

(2015) Ruorong Yan et al.   GENES & DEVELOPMENT

Approaches to Improving Cardiac Structure and Function During and After an Acute Myocardial Infarction

(2015) Robert A. Kloner et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Role of copper in regression of cardiac hypertrophy

(2015) Lily Zheng et al.   PHARMACOLOGY & THERAPEUTICS

Paracrine Action of Mesenchymal Stem Cells Revealed by Single Cell Gene Profiling in Infarcted Murine Hearts

(2015) Yan Yao et al.   PLoS One

Evaluation of Hypoxia With Copper-Labeled Diacetyl-bis(N-Methylthiosemicarbazone)

(2015) Suzanne E. Lapi et al.   SEMINARS IN NUCLEAR MEDICINE

Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function

(2015) Gin-Fu Chen et al.   Scientific Reports

HIF-1 Signaling in Drug Resistance to Chemotherapy

(2014) N.A. Warfel et al.   CURRENT MEDICINAL CHEMISTRY

Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression

(2014) Zhen Zhang et al.   Metallomics

Increasing Intracellular Bioavailable Copper Selectively Targets Prostate Cancer Cells

(2013) Michael A. Cater et al.   ACS Chemical Biology

Hypoxia-Inducible Factor 1 and Cardiovascular Disease

(2013) Gregg L. Semenza   Annual Review of Physiology

Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment

(2013) Jun Lu et al.   Cardiovascular Diabetology

Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats

(2013) Lin Zhang et al.   Cardiovascular Diabetology

Copper promotion of angiogenesis in isolated rat aortic ring: role of vascular endothelial growth factor

(2013) Qi-feng Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

CTR1 Silencing Inhibits Angiogenesis by Limiting Copper Entry into Endothelial Cells

(2013) Gomathy Narayanan et al.   PLoS One

Angiogenesis in the Infarcted Myocardium

(2012) Clement Cochain et al.   ANTIOXIDANTS & REDOX SIGNALING

Ischemia-induced Copper Loss and Suppression of Angiogenesis in the Pathogenesis of Myocardial Infarction

(2012) Weihong He et al.   Cardiovascular Toxicology

Reduced microvascular density in non-ischemic myocardium of patients with recent non-ST-segment-elevation myocardial infarction

(2012) Duncan J. Campbell et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Neural Stem Cells Genetically Modified to Overexpress Cu/Zn-Superoxide Dismutase Enhance Amelioration of Ischemic Stroke in Mice

(2012) Hiroyuki Sakata et al.   STROKE

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Copper stimulates growth of human umbilical vein endothelial cells in a vascular endothelial growth factor-independent pathway

(2011) Shun Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hypoxia inducible factor 1 (HIF-1) and cardioprotection

(2010) Demet Tekin et al.   ACTA PHARMACOLOGICA SINICA

Cardiac-Specific Overexpression of HIF-1α Prevents Deterioration of Glycolytic Pathway and Cardiac Remodeling in Streptozotocin-Induced Diabetic Mice

(2010) Wanli Xue et al.   AMERICAN JOURNAL OF PATHOLOGY

Complementary Actions of Inhibitors of Angiopoietin-2 and VEGF on Tumor Angiogenesis and Growth

(2010) H. Hashizume et al.   CANCER RESEARCH

Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy

(2010) Javid Moslehi et al.   CIRCULATION

COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

(2010) Bart van de Sluis et al.   JOURNAL OF CLINICAL INVESTIGATION

SDF-1α as a therapeutic stem cell homing factor in myocardial infarction

(2010) Santhosh K. Ghadge et al.   PHARMACOLOGY & THERAPEUTICS

Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth

(2009) Patrick Nasarre et al.   CANCER RESEARCH

Angiogenic and Vascular Modulation by Extracellular Matrix Cleavage Products

(2009) Frank Suhr et al.   CURRENT PHARMACEUTICAL DESIGN

The Extracellular Matrix of Blood Vessels

(2009) Johannes Eble et al.   CURRENT PHARMACEUTICAL DESIGN

Nuclear-Cytosolic Transport of COMMD1 Regulates NF-κB and HIF-1 Activity

(2009) Patricia A. J. Muller et al.   TRAFFIC

Serum Zinc and Copper Levels in Ischemic Cardiomyopathy

(2008) Mohammad Shokrzadeh et al.   BIOLOGICAL TRACE ELEMENT RESEARCH