Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment

Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice

(2012) Hao Wei et al.   ATHEROSCLEROSIS

Selective Divalent Copper Chelation for the Treatment of Diabetes Mellitus

(2012) G. J.S. Cooper   CURRENT MEDICINAL CHEMISTRY

Cellular Responses to the Metal-Binding Properties of Metformin

(2012) L. Logie et al.   DIABETES

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications

(2012) R. Nagai et al.   DIABETES

Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis

(2011) Vasundhara Kain et al.   Cardiovascular Diabetology

Therapeutic Potential of Copper Chelation with Triethylenetetramine in Managing Diabetes Mellitus and Alzheimerʼs Disease

(2011) Garth J.S. Cooper   DRUGS

Copper(II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments

(2010) J. Lu et al.   DIABETOLOGIA

Pharmacokinetics, Pharmacodynamics, and Metabolism of Triethylenetetramine in Healthy Human Participants: An Open-Label Trial

(2010) Jun Lu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Illuminating the molecular basis of diabetic arteriopathy: A proteomic comparison of aortic tissue from diabetic and healthy rats

(2010) Mia Jüllig et al.   PROTEOMICS

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study

(2009) G. J. S. Cooper et al.   DIABETOLOGIA

Pharmacokinetic and Pharmacodynamic Modeling of a Copper-Selective Chelator (TETA) in Healthy Adults

(2009) Hea-Young Cho et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats

(2009) Deming Gong et al.   PROTEOMICS

Altered Calcium Homeostasis Does Not Explain the Contractile Deficit of Diabetic Cardiomyopathy

(2008) L. Zhang et al.   DIABETES

A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes

(2008) D. Gong et al.   DIABETOLOGIA

Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardium

(2008) Peter Kellman et al.   MAGNETIC RESONANCE IN MEDICINE

Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats

(2008) Mia Jüllig et al.   PROTEOMICS