LC3-associated phagocytosis: a crucial mechanism for antifungal host defence againstAspergillus fumigatus

Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease

(2016) Georgios Chamilos et al.   Autophagy

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

(2016) Tonia Akoumianaki et al.   Cell Host & Microbe

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients

(2016) Sébastien Imbert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan

(2016) Nida S. Khan et al.   JOURNAL OF IMMUNOLOGY

Apoptotic-likeLeishmaniaexploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination

(2015) Peter Crauwels et al.   Autophagy

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus

(2015) S. Herbst et al.   EMBO Molecular Medicine

Virulence determinants of the human pathogenic fungusAspergillus fumigatusprotect against soil amoeba predation

(2015) Falk Hillmann et al.   ENVIRONMENTAL MICROBIOLOGY

Rab14 Regulates Maturation of Macrophage Phagosomes Containing the Fungal Pathogen Candida albicans and Outcome of the Host-Pathogen Interaction

(2015) Blessing Okai et al.   INFECTION AND IMMUNITY

Rubicon swaps autophagy for LAP

(2015) Keith B. Boyle et al.   NATURE CELL BIOLOGY

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Invasive Aspergillosis: Epidemiology, Clinical Aspects, and Treatment

(2015) Carol Kauffman et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Autophagy Is Required for Neutrophil-Mediated Inflammation

(2015) Abhisek Bhattacharya et al.   Cell Reports

IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

(2015) Alayna K. Caffrey et al.   PLoS Pathogens

Screening in Planarians Identifies MORN2 as a Key Component in LC3-Associated Phagocytosis and Resistance to Bacterial Infection

(2014) Prasad Abnave et al.   Cell Host & Microbe

The Role of Interleukin-1 Family Members in the Host Defence Against Aspergillus fumigatus

(2014) Mark S. Gresnigt et al.   MYCOPATHOLOGIA

Bacteria–autophagy interplay: a battle for survival

(2014) Ju Huang et al.   NATURE REVIEWS MICROBIOLOGY

Host and Bacterial Proteins That Repress Recruitment of LC3 to Shigella Early during Infection

(2014) Leigh A. Baxt et al.   PLoS One

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interference of Aspergillus fumigatus with the immune response

(2014) Thorsten Heinekamp et al.   Seminars in Immunopathology

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation

(2014) Judith M. Bain et al.   mBio

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing

(2013) Susana Romao et al.   JOURNAL OF CELL BIOLOGY

Corticosteroids Block Autophagy Protein Recruitment in Aspergillus fumigatus Phagosomes via Targeting Dectin-1/Syk Kinase Signaling

(2013) I. Kyrmizi et al.   JOURNAL OF IMMUNOLOGY

Pulmonary immune responses toAspergillus fumigatusin an immunocompetent mouse model of repeated exposures

(2013) Amanda D. Buskirk et al.   Journal of Immunotoxicology

Pattern recognition receptors and their role in invasive aspergillosis

(2012) Mark S. Gresnigt et al.   Annals of the New York Academy of Sciences

Infections associated with chronic granulomatous disease: linking genetics to phenotypic expression

(2012) Josef Ben-Ari et al.   Expert Review of Anti-Infective Therapy

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

How nascent phagosomes mature to become phagolysosomes

(2012) Gregory D. Fairn et al.   TRENDS IN IMMUNOLOGY

The role of dendritic cells in the innate recognition of pathogenic fungi (A. fumigatus,C. neoformansandC. albicans)

(2012) Zaida G. Ramirez-Ortiz et al.   Virulence

LC3-Associated Phagocytosis (LAP): Connections with Host Autophagy

(2012) Shu-chin Lai et al.   Cells

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

(2011) Peiyuan Li et al.   CANCER LETTERS

Cooperation of p40phoxwith p47phoxfor Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis

(2011) Takehiko Ueyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low Interleukin-17A Production in Response to Fungal Pathogens in Patients with Chronic Granulomatous Disease

(2011) Sanne P. Smeekens et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

(2010) C. Cunha et al.   BLOOD

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

TLR9 Is Actively Recruited to Aspergillus fumigatus Phagosomes and Requires the N-Terminal Proteolytic Cleavage Domain for Proper Intracellular Trafficking

(2010) P. V. Kasperkovitz et al.   JOURNAL OF IMMUNOLOGY

Epidemiology and Outcome of Invasive Fungal Diseases in Patients With Chronic Granulomatous Disease

(2010) Julien Beauté et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Reactive oxygen species-independent activation of the IL-1  inflammasome in cells from patients with chronic granulomatous disease

(2010) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Aspergillus fumigatus Conidial Melanin Modulates Host Cytokine Response

(2009) Louis Y.A. Chai et al.   IMMUNOBIOLOGY

Anti-Aspergillushuman host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity

(2009) Louis Y. A. Chai et al.   IMMUNOLOGY

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via Autophagy

(2009) Munir A. Al-Zeer et al.   PLoS One

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-Like Receptor 9 Modulates Immune Responses to Aspergillus fumigatus Conidia in Immunodeficient and Allergic Mice

(2008) H. Ramaprakash et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

(2008) Z. G. Ramirez-Ortiz et al.   INFECTION AND IMMUNITY

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

(2008) Michela G. Schäppi et al.   Seminars in Immunopathology