5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

(2016) Xu Wang et al.   JOURNAL OF NEUROSCIENCE

Temporal retinal transcriptome and systems biology analysis identifies key pathways and hub genes in Staphylococcus aureus endophthalmitis

(2016) Deepa Rajamani et al.   Scientific Reports

Effects of pre-analytical processes on blood samples used in metabolomics studies

(2015) Peiyuan Yin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Enhanced M1 and Impaired M2 Macrophage Polarization and Reduced Mitochondrial Biogenesis via Inhibition of AMP Kinase in Chronic Kidney Disease

(2015) Cong Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Antidiabetic agents: Potential anti-inflammatory activity beyond glucose control

(2015) A.J. Scheen et al.   DIABETES & METABOLISM

Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria

(2015) Salai Madhumathi Parkunan et al.   INFECTION AND IMMUNITY

In Vivo Role of TLR2 and MyD88 Signaling in Eliciting Innate Immune Responses in Staphylococcal Endophthalmitis

(2015) D. Talreja et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis

(2015) Laila M. Poisson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AICAR Enhances the Phagocytic Ability of Macrophages towards Apoptotic Cells through P38 Mitogen Activated Protein Kinase Activation Independent of AMP-Activated Protein Kinase

(2015) Hui Quan et al.   PLoS One

Microglial Activation Promotes Cell Survival in Organotypic Cultures of Postnatal Mouse Retinal Explants

(2015) Rosa M. Ferrer-Martín et al.   PLoS One

Metformin limits the adipocyte tumor-promoting effect on ovarian cancer

(2015) Calvin Tebbe et al.   Oncotarget

Intravitreal Injection of the Chimeric Phage Endolysin Ply187 Protects Mice from Staphylococcus aureus Endophthalmitis

(2014) Pawan Kumar Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Translating Glycolytic Metabolism to Innate Immunity in Dendritic Cells

(2014) Mario Cortese et al.   Cell Metabolism

AMP-activated protein kinase activators in diabetic ulcers: from animal studies to Phase II drugs under investigation

(2014) Jiun-Tsai Lin et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Identification of novel omega-3 fatty acid-derived bioactive metabolites based on a targeted lipidomics approach

(2014) Yosuke Isobe et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Metabolic profiling in diabetes

(2014) Karsten Suhre   JOURNAL OF ENDOCRINOLOGY

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

(2014) D. Grahame Hardie   JOURNAL OF INTERNAL MEDICINE

Antibacterial responses of retinal Müller glia: production of antimicrobial peptides, oxidative burst and phagocytosis

(2014) Pawan Singh et al.   Journal of Neuroinflammation

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(2014) Dae Won Park et al.   MOLECULAR MEDICINE

AMPK Inhibition Blocks ROS-NFκB Signaling and Attenuates Endotoxemia-Induced Liver Injury

(2014) Yuan Guo et al.   PLoS One

AMPK-NF-κB Axis in the Photoreceptor Disorder during Retinal Inflammation

(2014) Mamoru Kamoshita et al.   PLoS One

A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implications for their use as bioenergetic biomarkers

(2014) Philip A. Kramer et al.   Redox Biology

AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

(2013) Madhumita Dandapani et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

(2013) Rémi Mounier et al.   Cell Metabolism

Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

(2013) Silvia Bijland et al.   CLINICAL SCIENCE

Muller Glia in Retinal Innate Immunity: A Perspective on Their Roles in Endophthalmitis

(2013) Ashok Kumar et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Role of heparan sulfate in ocular diseases

(2013) Paul J. Park et al.   EXPERIMENTAL EYE RESEARCH

An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy

(2013) Xavier Palomer et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Vitronectin Inhibits Efferocytosis through Interactions with Apoptotic Cells as well as with Macrophages

(2013) H.-B. Bae et al.   JOURNAL OF IMMUNOLOGY

Capsaicin induces apoptosis in human osteosarcoma cells through AMPK-dependent and AMPK-independent signaling pathways

(2013) Hui Ying et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Defective Phagocytosis in Airways Disease

(2012) Louise E. Donnelly et al.   CHEST

Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

(2012) Ian P Salt et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Toll-Like Receptor 2 Ligand Pretreatment Attenuates Retinal Microglial Inflammatory Response but Enhances Phagocytic Activity toward Staphylococcus aureus

(2012) Travis Kochan et al.   INFECTION AND IMMUNITY

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

(2012) Branden Stansley et al.   Journal of Neuroinflammation

AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation

(2012) Johanna T Lanner et al.   NATURE MEDICINE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Correction: Retinal Muller Glia Initiate Innate Response to Infectious Stimuli via Toll-Like Receptor Signaling

(2012) Ashok Kumar et al.   PLoS One

AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

(2011) Hong-Beom Bae et al.   FASEB JOURNAL

TLR2 Mediates the Innate Response of Retinal Muller Glia to Staphylococcus aureus

(2011) N. Shamsuddin et al.   JOURNAL OF IMMUNOLOGY

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

5′-Adenosine Monophosphate-Activated Protein Kinase–Mammalian Target of Rapamycin Axis As Therapeutic Target for Age-Related Macular Degeneration

(2011) Juha M.T. Hyttinen et al.   REJUVENATION RESEARCH

Urokinase-Type Plasminogen Activator Inhibits Efferocytosis of Neutrophils

(2010) Yanping Yang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapid Expansion of Intravitreal Drug Injection Procedures, 2000 to 2008

(2010) Robert J. Campbell   ARCHIVES OF OPHTHALMOLOGY

Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans

(2010) Marie-Soleil Gauthier et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

(2010) Aiping Bai et al.   BIOCHEMICAL PHARMACOLOGY

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

AMPK inhibition in health and disease

(2010) Benoit Viollet et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase

(2010) Sofia Theodoropoulou et al.   FASEB JOURNAL

5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB

(2010) Marina Katerelos et al.   IMMUNOLOGY AND CELL BIOLOGY

Novel Anti-Inflammatory Action of 5-Aminoimidazole-4-carboxamide Ribonucleoside with Protective Effect in Dextran Sulfate Sodium-Induced Acute and Chronic Colitis

(2010) A. Bai et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells

(2009) Michael M. Myerburg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

(2009) Narender Nath et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells

(2009) A. Peairs et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

(2009) N. Nath et al.   JOURNAL OF IMMUNOLOGY

Toll‐like Receptor 2 Ligand–Induced Protection against Bacterial Endophthalmitis

(2009) Ashok Kumar et al.   JOURNAL OF INFECTIOUS DISEASES

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury

(2008) Xia Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA

 B-Crystallin Protects Retinal Tissue during Staphylococcus aureus- Induced Endophthalmitis

(2008) E. A. Whiston et al.   INFECTION AND IMMUNITY