A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway

(2013) Jonathan M. Coquet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selection of Self-Reactive T Cells in the Thymus

(2012) Gretta L. Stritesky et al.   Annual Review of Immunology

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold

(2012) T. L. Stephen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regenerative capacity of adult cortical thymic epithelial cells

(2012) I. Rode et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

(2012) Graham Anderson et al.   TRENDS IN IMMUNOLOGY

c-Ski in health and disease

(2011) Carine Bonnon et al.   CELL AND TISSUE RESEARCH

The thymus: “Interactive teaching during lymphopoiesis”

(2011) Willem van Ewijk   IMMUNOLOGY LETTERS

NKAP is required for T cell maturation and acquisition of functional competency

(2011) Fan-Chi Hsu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells

(2011) Jiyeon S. Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T cell lineage commitment in the thymus

(2011) Ludger Klein et al.   SEMINARS IN IMMUNOLOGY

B7/CD28 in Central Tolerance: Costimulation Promotes Maturation of Regulatory T Cell Precursors and Prevents Their Clonal Deletion

(2011) Maria Hinterberger et al.   Frontiers in Immunology

How thymic antigen presenting cells sample the body's self-antigens

(2010) Jens Derbinski et al.   CURRENT OPINION IN IMMUNOLOGY

Aire and T cell development

(2010) Mark S Anderson et al.   CURRENT OPINION IN IMMUNOLOGY

Cytokine crosstalk for thymic medulla formation

(2010) Takeshi Nitta et al.   CURRENT OPINION IN IMMUNOLOGY

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes

(2010) Gerald Wirnsberger et al.   IMMUNOLOGY AND CELL BIOLOGY

TCR-dependent differentiation of thymic Foxp3+cells is limited to small clonal sizes

(2009) Monica W.L. Leung et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Activation Threshold of CD4+ T Cells Is Defined by TCR/Peptide-MHC Class II Interactions in the Thymic Medulla

(2009) T. L. Stephen et al.   JOURNAL OF IMMUNOLOGY

Stabilized  -Catenin in Thymic Epithelial Cells Blocks Thymus Development and Function

(2009) S. Zuklys et al.   JOURNAL OF IMMUNOLOGY

Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation

(2009) Benjamin R Marks et al.   NATURE IMMUNOLOGY

Intraclonal competition limits the fate determination of regulatory T cells in the thymus

(2009) Jhoanne L Bautista et al.   NATURE IMMUNOLOGY

The impact of negative selection on thymocyte migration in the medulla

(2009) Marie Le Borgne et al.   NATURE IMMUNOLOGY

CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens

(2009) T. Nitta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-  signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

(2008) M. M. Hauri-Hohl et al.   BLOOD

TGF-β: A Master of All T Cell Trades

(2008) Ming O. Li et al.   CELL

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

(2008) Yu Hikosaka et al.   IMMUNITY

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

(2008) Magali Irla et al.   IMMUNITY

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

(2008) A. Liston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development

(2008) P. J. Spence et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA