Does Vitamin C Deficiency Increase Lifestyle-Associated Vascular Disease Progression? Evidence Based on Experimental and Clinical Studies

Vitamin status in morbidly obese patients: a cross-sectional study

(2018) Erlend T Aasheim et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer–Norfolk prospective population study

(2018) Phyo K Myint et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Influence of vitamin C on markers of oxidative stress in the earliest period of ischemic stroke

(2014) Monika Lagowska-Lenard et al.   Pharmacological Reports

Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials

(2012) Stephen P Juraschek et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nitroso-Redox Status and Vascular Function in Marginal and Severe Ascorbate Deficiency

(2012) Maria-Francisca Garcia-Saura et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function

(2012) Alan Mortensen et al.   BIOMARKERS

Second-Hand Tobacco Smoke and Cardiovascular Disease Risk

(2012) Andrew Dunbar et al.   Cardiology in Review

Independent Association Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in the US Population

(2012) Maria Stepanova et al.   Clinical Gastroenterology and Hepatology

Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans?

(2012) Balz Frei et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Prevalence of Prediabetes and Diabetes and Metabolic Profile of Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

(2012) C. Ortiz-Lopez et al.   DIABETES CARE

Proinflammatory and oxidative stress markers in patients submitted to Roux-en-Y gastric bypass after 1 year of follow-up

(2012) V R G da Silva et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status

(2012) Angela Ladurner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: results from a cross-sectional study

(2012) Olga García et al.   Nutrition & Metabolism

Interventions with Vitamins B6, B12 and C in Pregnancy

(2012) Daphna K. Dror et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

eNOS Protects from Atherosclerosis Despite Relevant Superoxide Production by the Enzyme in apoE−/− Mice

(2012) Padmapriya Ponnuswamy et al.   PLoS One

Molecular and Cellular Mechanisms of Cigarette Smoke-Induced Myocardial Injury: Prevention by Vitamin C

(2012) Archita Das et al.   PLoS One

The role of tetrahydrobiopterin in inflammation and cardiovascular disease

(2012) E. McNeill et al.   THROMBOSIS AND HAEMOSTASIS

Oxidized Low-Density Lipoprotein and Atherosclerosis Implications in Antioxidant Therapy

(2011) Sona Mitra et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases

(2011) Rocio I. R. Macias et al.   BRITISH JOURNAL OF NUTRITION

Intake of antioxidants and risk of type 2 diabetes in a cohort of male smokers

(2011) M K Kataja-Tuomola et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Prevention of pre-eclampsia with low-dose aspirin or vitamins C and E in women at high or low risk: a systematic review with meta-analysis

(2011) A. Cristina Rossi et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Vitamin C Prevents Cigarette Smoke Induced Atherosclerosis in Guinea Pig Model

(2011) Tanusree Ray et al.   Journal of Atherosclerosis and Thrombosis

Pancreatic insulin release in vitamin C-deficient senescence marker protein-30/gluconolactonase knockout mice

(2011) Takafumi Senmaru et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The interaction of hepatic lipid and glucose metabolism in liver diseases

(2011) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

Vitamin C Status Is Related to Proinflammatory Responses and Impaired Vascular Endothelial Function in Healthy, College-Aged Lean and Obese Men

(2011) Eunice Mah et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Vitamin C modulates the interaction between adipocytes and macrophages

(2011) Diego F. Garcia-Diaz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Prevalence and Risk Factors for Vitamin C Deficiency in North and South India: A Two Centre Population Based Study in People Aged 60 Years and Over

(2011) Ravilla D. Ravindran et al.   PLoS One

Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells

(2011) Henriette Frikke-Schmidt et al.   TOXICOLOGY LETTERS

Oxidant mechanisms in childhood obesity: the link between inflammation and oxidative stress

(2011) Pilar Codoñer-Franch et al.   Translational Research

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of l-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants

(2010) Nicholas J Timpson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency

(2010) Leah E Cahill et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Atorvastatin and Antioxidants for the Treatment of Nonalcoholic Fatty Liver Disease: The St Francis Heart Study Randomized Clinical Trial

(2010) Temitope Foster et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Oxidative Stress as Pathogenesis of Cardiovascular Risk Associated with Metabolic Syndrome

(2010) Hajime Otani   ANTIOXIDANTS & REDOX SIGNALING

High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

(2010) Henriette Frikke-Schmidt et al.   BRITISH JOURNAL OF NUTRITION

Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling

(2010) Ulrich Förstermann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Obesity, Inflammation, and Cardiovascular Risk

(2010) P Mathieu et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Vitamin C levels in blood are influenced by polymorphisms in glutathione S-transferases

(2010) Alexandra Horska et al.   EUROPEAN JOURNAL OF NUTRITION

Selective macrophage ascorbate deficiency suppresses early atherosclerosis

(2010) Vladimir R. Babaev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intravenous Ascorbic Acid Infusion Improves Myocardial Perfusion Grade During Elective Percutaneous Coronary Intervention

(2010) Stefania Basili et al.   JACC-Cardiovascular Interventions

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes

(2010) D F Garcia-Diaz et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Oxidized LDL up-regulates the ascorbic acid transporter SVCT2 in endothelial cells

(2010) James M. May et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Evidence-based criteria in the nutritional context

(2010) Jeffrey Blumberg et al.   NUTRITION REVIEWS

The true cost of in-patient obesity: impact of obesity on inflammatory stress and morbidity

(2010) Robert F. Grimble   PROCEEDINGS OF THE NUTRITION SOCIETY

Vitamin C, resveratrol and lipoic acid actions on isolated rat liver mitochondria: all antioxidants but different

(2010) M. Pilar Valdecantos et al.   REDOX REPORT

Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults

(2009) Sébastien Czernichow et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes

(2009) Michal Odermarsky et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003–2004 National Health and Nutrition Examination Survey (NHANES)

(2009) Rosemary L Schleicher et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture

(2009) Henriette Frikke-Schmidt et al.   ANALYTICAL BIOCHEMISTRY

Vitamin C intake attenuates the degree of experimental atherosclerosis induced by periodontitis in the rat by decreasing oxidative stress

(2009) Daisuke Ekuni et al.   ARCHIVES OF ORAL BIOLOGY

Serum vitamin C concentration and hs-CRP level in middle-aged Japanese men and women

(2009) Yoshimi Kubota et al.   ATHEROSCLEROSIS

Role of Marginal Vitamin C Deficiency in Atherogenesis:In VivoModels and Clinical Studies

(2009) Henriette Frikke-Schmidt et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Some Cyclin-Dependent Kinase Inhibitors-Related Genes Are Regulated by Vitamin C in a Model of Diet-Induced Obesity

(2009) Noemí Boqué et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

(2009) Jens Lykkesfeldt et al.   BRITISH JOURNAL OF NUTRITION

Vitamin C restores healthy aging in a mouse model for Werner syndrome

(2009) Laurent Massip et al.   FASEB JOURNAL

Vitamins E and C in the prevention of cardiovascular disease and cancer in men

(2009) L. Jackson Roberts et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of antioxidant supplementation on insulin sensitivity, endothelial adhesion molecules, and oxidative stress in normal-weight and overweight young adults

(2009) Heather K. Vincent et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Obesity and Type 2 diabetes: Slow down!—Can metabolic deceleration protect the islet beta cell from excess nutrient-induced damage?

(2009) S. Andrikopoulos   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

Plasma Vitamin C Level, Fruit and Vegetable Consumption, and the Risk of New-Onset Type 2 Diabetes MellitusThe European Prospective Investigation of Cancer–Norfolk Prospective Study

(2008) Anne-Helen Harding   ARCHIVES OF INTERNAL MEDICINE

The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level

(2008) Gladys Block et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: A randomized, controlled trial

(2008) Valerio Nobili et al.   HEPATOLOGY

Vitamin C Supplementation Influences Body Fat Mass and Steroidogenesis-Related Genes when Fed a High-Fat Diet

(2008) Campión et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Vitamins E and C in the Prevention of Cardiovascular Disease in Men

(2008) Howard D. Sesso   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Quantitative Regulation of Intracellular Endothelial Nitric-oxide Synthase (eNOS) Coupling by Both Tetrahydrobiopterin-eNOS Stoichiometry and Biopterin Redox Status

(2008) Mark J. Crabtree et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population

(2008) A. Mosdol et al.   JOURNAL OF PUBLIC HEALTH

Inflammation in the vascular bed: Importance of vitamin C

(2008) Rene Aguirre et al.   PHARMACOLOGY & THERAPEUTICS

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

(2008) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

(2008) Ulrich Förstermann   Nature clinical practice. Cardiovascular medicine