X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis

(2011) M. Ananthanarayanan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

(2011) A. M. Jankowska et al.   BLOOD

Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

(2011) T. Sengoku et al.   GENES & DEVELOPMENT

Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

(2011) Lukas D. Wartman et al.   JOURNAL OF CLINICAL INVESTIGATION

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Genetic engineering of human pluripotent cells using TALE nucleases

(2011) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Genetic heterogeneity and chromatin modifiers in renal clear cell carcinoma

(2010) Peter Staller   Future Oncology

The histone demethylase UTX enables RB-dependent cell fate control

(2010) J. K. Wang et al.   GENES & DEVELOPMENT

Jmjd3 activates Mash1 gene in RA-induced neuronal differentiation of P19 cells

(2010) Jin-po Dai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Jmjd3 and UTX Play a Demethylase-Independent Role in Chromatin Remodeling to Regulate T-Box Family Member-Dependent Gene Expression

(2010) Sara A. Miller et al.   MOLECULAR CELL

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

(2010) Ryan D Morin et al.   NATURE GENETICS

ASCOM Controls Farnesoid X Receptor Transactivation through Its Associated Histone H3 Lysine 4 Methyltransferase Activity

(2009) Dae-Hwan Kim et al.   MOLECULAR ENDOCRINOLOGY

Crucial Roles for Interactions between MLL3/4 and INI1 in Nuclear Receptor Transactivation

(2009) Seunghee Lee et al.   MOLECULAR ENDOCRINOLOGY

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

(2009) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Sex-Specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons

(2008) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse

(2008) S MARKOULAKI et al.   METHODS

Activating Signal Cointegrator-2 Is an Essential Adaptor to Recruit Histone H3 Lysine 4 Methyltransferases MLL3 and MLL4 to the Liver X Receptors

(2008) Seunghee Lee et al.   MOLECULAR ENDOCRINOLOGY

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

(2008) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA