E-cadherin junctions as active mechanical integrators in tissue dynamics

Actin-Delimited Adhesion-Independent Clustering of E-Cadherin Forms the Nanoscale Building Blocks of Adherens Junctions

(2015) Yao Wu et al.   DEVELOPMENTAL CELL

Direct laser manipulation reveals the mechanics of cell contacts in vivo

(2015) Kapil Bambardekar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinants of Fluidlike Behavior and Effective Viscosity in Cross-Linked Actin Networks

(2014) Taeyoon Kim et al.   BIOPHYSICAL JOURNAL

Tension-Sensitive Actin Assembly Supports Contractility at the Epithelial Zonula Adherens

(2014) Joanne M. Leerberg et al.   CURRENT BIOLOGY

Diverse and dynamic sources and sinks in gradient formation and directed migration

(2014) Danfeng Cai et al.   CURRENT OPINION IN CELL BIOLOGY

Apical constriction: themes and variations on a cellular mechanism driving morphogenesis

(2014) A. C. Martin et al.   DEVELOPMENT

Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens

(2014) Siew Ping Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho GTPase and Shroom direct planar polarized actomyosin contractility during convergent extension

(2014) Sérgio de Matos Simões et al.   JOURNAL OF CELL BIOLOGY

 -Catenin cytomechanics - role in cadherin-dependent adhesion and mechanotransduction

(2014) A. K. Barry et al.   JOURNAL OF CELL SCIENCE

Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions

(2014) W. Engl et al.   NATURE CELL BIOLOGY

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement

(2014) A. Shindo et al.   SCIENCE

The minimal cadherin-catenin complex binds to actin filaments under force

(2014) C. D. Buckley et al.   SCIENCE

Resolving the molecular mechanism of cadherin catch bond formation

(2014) Kristine Manibog et al.   Nature Communications

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Principles of E-Cadherin Supramolecular Organization In Vivo

(2013) Binh-An Truong Quang et al.   CURRENT BIOLOGY

Oscillation and Polarity of E-Cadherin Asymmetries Control Actomyosin Flow Patterns during Morphogenesis

(2013) Romain Levayer et al.   DEVELOPMENTAL CELL

Septins Regulate the Contractility of the Actomyosin Ring to Enable Adherens Junction Remodeling during Cytokinesis of Epithelial Cells

(2013) Nabila Founounou et al.   DEVELOPMENTAL CELL

Adhesion Disengagement Uncouples Intrinsic and Extrinsic Forces to Drive Cytokinesis in Epithelial Tissues

(2013) Charlène Guillot et al.   DEVELOPMENTAL CELL

Interplay between the Dividing Cell and Its Neighbors Regulates Adherens Junction Formation during Cytokinesis in Epithelial Tissue

(2013) Sophie Herszterg et al.   DEVELOPMENTAL CELL

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

(2013) Rashmi Priya et al.   DIFFERENTIATION

Adherens junctions determine the apical position of the midbody during follicular epithelial cell division

(2013) Eurico Morais-de-Sá et al.   EMBO REPORTS

FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions

(2013) Vivian W. Tang et al.   JOURNAL OF CELL BIOLOGY

Monomeric α-catenin links cadherin to the actin cytoskeleton

(2013) Ridhdhi Desai et al.   NATURE CELL BIOLOGY

Apical domain polarization localizes actin–myosin activity to drive ratchet-like apical constriction

(2013) Frank M. Mason et al.   NATURE CELL BIOLOGY

Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly

(2013) Pedro Campinho et al.   NATURE CELL BIOLOGY

Cell intercalation from top to bottom

(2013) Elise Walck-Shannon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biomechanics of cell adhesion: how force regulates the lifetime of adhesive bonds at the single molecule level

(2013) Sabyasachi Rakshit et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Hydrodynamics of soft active matter

(2013) M. C. Marchetti et al.   REVIEWS OF MODERN PHYSICS

Mechanics of Epithelial Tissue Homeostasis and Morphogenesis

(2013) C. Guillot et al.   SCIENCE

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

Cadherin junctions and their cytoskeleton(s)

(2012) William M Brieher et al.   CURRENT OPINION IN CELL BIOLOGY

Cytokinesis mechanics and mechanosensing

(2012) Hoku West-Foyle et al.   Cytoskeleton

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding

(2012) Eliana Marinari et al.   NATURE

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

(2012) Aparna Ratheesh et al.   NATURE CELL BIOLOGY

E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch

(2012) N. Borghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ideal, catch, and slip bonds in cadherin adhesion

(2012) S. Rakshit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex

(2012) M. P. Murrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions

(2012) Minna Roh-Johnson et al.   SCIENCE

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

(2012) J.-L. Maitre et al.   SCIENCE

Forces Driving Epithelial Spreading in Zebrafish Gastrulation

(2012) M. Behrndt et al.   SCIENCE

Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway

(2012) F. Bosveld et al.   SCIENCE

Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells

(2012) Georgios Trichas et al.   PLOS BIOLOGY

Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis

(2011) Thomas Lecuit et al.   Annual Review of Cell and Developmental Biology

Cadherin–actin interactions at adherens junctions

(2011) Shigenobu Yonemura   CURRENT OPINION IN CELL BIOLOGY

Spatial, temporal and molecular hierarchies in the link between death, delamination and dorsal closure

(2011) S. Muliyil et al.   DEVELOPMENT

Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin

(2011) Andrew L. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway

(2011) Eva M. Kovacs et al.   NATURE CELL BIOLOGY

Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis

(2011) Romain Levayer et al.   NATURE CELL BIOLOGY

Active multistage coarsening of actin networks driven by myosin motors

(2011) M. Soares e Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Productive tension: force-sensing and homeostasis of cell–cell junctions

(2011) Guillermo A. Gomez et al.   TRENDS IN CELL BIOLOGY

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

(2010) Benoît Aigouy et al.   CELL

Sequential Activation of Apical and Basolateral Contractility Drives Ascidian Endoderm Invagination

(2010) Kristin Sherrard et al.   CURRENT BIOLOGY

Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure

(2010) G. B. Blanchard et al.   DEVELOPMENT

Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

(2010) Sérgio de Matos Simões et al.   DEVELOPMENTAL CELL

Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction

(2010) Cory Bolinger et al.   DEVELOPMENTAL DYNAMICS

Unconventional Processive Mechanics of Non-muscle Myosin IIB

(2010) Melanie F. Norstrom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VASP is a processive actin polymerase that requires monomeric actin for barbed end association

(2010) Scott D. Hansen et al.   JOURNAL OF CELL BIOLOGY

Integration of contractile forces during tissue invagination

(2010) Adam C. Martin et al.   JOURNAL OF CELL BIOLOGY

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

(2010) Quint le Duc et al.   JOURNAL OF CELL BIOLOGY

Cytoskeletal coherence requires myosin-IIA contractility

(2010) Y. Cai et al.   JOURNAL OF CELL SCIENCE

Robust Mechanosensing and Tension Generation by Myosin VI

(2010) Peiying Chuan et al.   JOURNAL OF MOLECULAR BIOLOGY

Planar polarized actomyosin contractile flows control epithelial junction remodelling

(2010) Matteo Rauzi et al.   NATURE

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

(2010) Mirjam Mayer et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

Two-step adhesive binding by classical cadherins

(2010) Oliver J Harrison et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure

(2009) Jerome Solon et al.   CELL

N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements

(2009) S. Nandadasa et al.   DEVELOPMENT

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

Active gels as a description of the actin‐myosin cytoskeleton

(2009) Jean‐François Joanny et al.   HFSP Journal

Characterization of the interface between normal and transformed epithelial cells

(2009) Catherine Hogan et al.   NATURE CELL BIOLOGY

An active biopolymer network controlled by molecular motors

(2009) G. H. Koenderink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Desmosome

(2009) E. Delva et al.   Cold Spring Harbor Perspectives in Biology

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT

A two-tiered mechanism for stabilization and immobilization of E-cadherin

(2008) Matthieu Cavey et al.   NATURE

Pulsed contractions of an actin–myosin network drive apical constriction

(2008) Adam C. Martin et al.   NATURE

Tensile forces govern germ-layer organization in zebrafish

(2008) M. Krieg et al.   NATURE CELL BIOLOGY

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

(2008) Matteo Rauzi et al.   NATURE CELL BIOLOGY

Apoptotic Force and Tissue Dynamics During Drosophila Embryogenesis

(2008) Y. Toyama et al.   SCIENCE

Touch, Grasp, Deliver and Control: Functional Cross-Talk Between Microtubules and Cell Adhesions

(2008) Anna Akhmanova et al.   TRAFFIC