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Title
Absent in melanoma 2 proteins in the development of cancer
Authors
Keywords
Colitis, Colorectal cancer, Inflammation, Inflammasome, PYHIN-family proteins
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 23, Pages 4383-4395
Publisher
Springer Nature
Online
2016-06-23
DOI
10.1007/s00018-016-2296-9
References
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- AIMing 2 Curtail Cancer
- (2015) Leah M. Rommereim et al. CELL
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- (2015) Si Ming Man et al. CELL
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- (2015) David P. Sester et al. JOURNAL OF IMMUNOLOGY
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- (2015) Sanjukta Chakrabarti et al. MEDICAL ONCOLOGY
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- (2015) Justin E Wilson et al. NATURE MEDICINE
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- (2015) Hui Kong et al. TUMOR BIOLOGY
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- (2015) Rongrong Liu et al. Oncotarget
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- (2015) Shuiqing Hu et al. Cell Reports
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- (2014) Dympna J. Connolly et al. BIOCHEMICAL PHARMACOLOGY
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- (2014) Sonal Khare et al. NATURE IMMUNOLOGY
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- (2014) C.-A. Yang et al. RHEUMATOLOGY
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- (2013) He LI et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
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- (2013) Larissa Ponomareva et al. MOLECULAR CANCER RESEARCH
- Sex Differences in Colorectal Cancer Survival: Population-Based Analysis of 164,996 Colorectal Cancer Patients in Germany
- (2013) Ondrej Majek et al. PLoS One
- Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
- (2013) J. G. M. Markle et al. SCIENCE
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- (2013) Qian Yin et al. Cell Reports
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- (2012) Yuudai Kondo et al. CANCER SCIENCE
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- (2012) Anliu Tang et al. CARCINOGENESIS
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- (2011) Grace Y. Chen et al. GASTROENTEROLOGY
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- (2011) Stefan A. Schattgen et al. IMMUNOLOGICAL REVIEWS
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- (2009) Georgios Patsos et al. INTERNATIONAL JOURNAL OF CANCER
- Female and Male Sex Hormones Differentially Regulate Expression of Ifi202, an Interferon-Inducible Lupus Susceptibility Gene within the Nba2 Interval
- (2009) R. Panchanathan et al. JOURNAL OF IMMUNOLOGY
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- (2009) T. L. Roberts et al. SCIENCE
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