Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients

Protection From Colorectal Cancer After Colonoscopy

(2013) Hermann Brenner et al.   ANNALS OF INTERNAL MEDICINE

HPV16 activates the AIM2 inflammasome in keratinocytes

(2013) M. Reinholz et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Inflammation-related induction of absent in melanoma 2 (AIM2) in vascular cells and atherosclerotic lesions suggests a role in vascular pathogenesis

(2013) Maani Hakimi et al.   JOURNAL OF VASCULAR SURGERY

AIM2, an IFN-Inducible Cytosolic DNA Sensor, in the Development of Benign Prostate Hyperplasia and Prostate Cancer

(2013) Larissa Ponomareva et al.   MOLECULAR CANCER RESEARCH

Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: A systemic review of current development, evidence, and recommendation

(2013) Clement Chung et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Expression Analysis of Aldehyde Dehydrogenase 1A1 (ALDH1A1) in Colon and Rectal Cancer in Association with Prognosis and Response to Chemotherapy

(2012) Christoph Kahlert et al.   ANNALS OF SURGICAL ONCOLOGY

Expression of oestrogen receptor β and prognosis of colorectal cancer

(2012) A Rudolph et al.   BRITISH JOURNAL OF CANCER

Biomarkers in Early-Stage Colorectal Cancer: Ready for Prime Time?

(2012) David Church et al.   DIGESTIVE DISEASES

Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions

(2012) Heleen D. de Koning et al.   EXPERIMENTAL DERMATOLOGY

Molecular Profiling of Colon Tumors: The Search for Clinically Relevant Biomarkers of Progression, Prognosis, Therapeutics, and Predisposition

(2011) Manny D. Bacolod et al.   ANNALS OF SURGICAL ONCOLOGY

Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion

(2011) Verena Kopfnagel et al.   EXPERIMENTAL DERMATOLOGY

Postoperative Adjuvant Chemotherapy for Stage II Colorectal Cancer: A Systematic Review of 12 Randomized Controlled Trials

(2011) Xiaojian Wu et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers

(2011) J Lee et al.   ONCOGENE

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

(2011) Y. Dombrowski et al.   Science Translational Medicine

Sensing Cytoplasmic Danger Signals by the Inflammasome

(2010) Emad S. Alnemri   JOURNAL OF CLINICAL IMMUNOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

Systemic Treatment of Colorectal Cancer

(2008) Brian M. Wolpin et al.   GASTROENTEROLOGY