Remarkable evolutionary relatedness among the enzymes and proteins from the α-amylase family

The Gram-negative bacterium Azotobacter chroococcum NCIMB 8003 employs a new glycoside hydrolase family 70 4,6-α-glucanotransferase enzyme (GtfD) to synthesize a reuteran like polymer from maltodextrins and starch

(2016) Joana Gangoiti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Structure and function of α-glucan debranching enzymes

(2016) Marie Sofie Møller et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Distribution of glucan-branching enzymes among prokaryotes

(2016) Eiji Suzuki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Sus operon: a model system for starch uptake by the human gut Bacteroidetes

(2016) Matthew H. Foley et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GH13 amylosucrases and GH70 branching sucrases, atypical enzymes in their respective families

(2016) Claire Moulis et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Unique carbohydrate binding platforms employed by the glucan phosphatases

(2016) Shane Emanuelle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Starch-degrading polysaccharide monooxygenases

(2016) Van V. Vu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

α-Glucosidases and α-1,4-glucan lyases: structures, functions, and physiological actions

(2016) Masayuki Okuyama et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Formation of starch in plant cells

(2016) Barbara Pfister et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Starch phosphorylation: insights and perspectives

(2016) Sebastian Mahlow et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structure–function relationships of family GH70 glucansucrase and 4,6-α-glucanotransferase enzymes, and their evolutionary relationships with family GH13 enzymes

(2016) Xiangfeng Meng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Exiguobacterium sibiricum 255-15 GtfC Enzyme Represents a Novel Glycoside Hydrolase 70 Subfamily of 4,6-α-Glucanotransferase Enzymes

(2015) Joana Gangoiti et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In silico analysis of family GH77 with focus on amylomaltases from borreliae and disproportionating enzymes DPE2 from plants and bacteria

(2015) Andrea Kuchtová et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Starch-processing enzymes – emphasis on thermostable 4-α-glucanotransferases

(2015) Nasir Ahmad et al.   BIOLOGIA

A novel GH13 subfamily of α-amylases with a pair of tryptophans in the helix α3 of the catalytic TIM-barrel, the LPDlx signature in the conserved sequence region V and a conserved aromatic motif at the C-terminus

(2015) Štefan Janeček et al.   BIOLOGIA

Carbohydrate-binding module tribes

(2015) Caio C. Carvalho et al.   BIOPOLYMERS

Inventory of the GH70 enzymes encoded byLeuconostoc citreumNRRL B-1299 - identification of three novel α-transglucosylases

(2015) Delphine Passerini et al.   FEBS Journal

Structural insights into the catalytic reaction that is involved in the reorientation of Trp238 at the substrate-binding site in GH13 dextran glucosidase

(2015) Momoko Kobayashi et al.   FEBS LETTERS

Structural elements responsible for the glucosidic linkage-selectivity of a glycoside hydrolase family 13 exo-glucosidase

(2015) Wataru Saburi et al.   FEBS LETTERS

Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation

(2015) Darrell Cockburn et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Identification of essential tryptophan in amylomaltase from Corynebacterium glutamicum

(2015) Wanitcha Rachadech et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase ofEscherichia coli

(2015) Simon C. Weiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Dissection of the Maltodextrin Disproportionation Cycle of theArabidopsisPlastidial Disproportionating Enzyme 1 (DPE1)

(2015) Ellis C. O'Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Mechanism of Laforin Function in Glycogen Dephosphorylation and Lafora Disease

(2015) Madushi Raththagala et al.   MOLECULAR CELL

SnRK1 fromArabidopsis thalianais an atypical AMPK

(2015) Shane Emanuelle et al.   PLANT JOURNAL

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

(2015) Leila Lo Leggio et al.   Nature Communications

Gene Analysis, Expression, and Characterization of an Intracellular α-Amylase from the Extremely Halophilic Archaeon Haloarcula japonica

(2015) Masahiko ONODERA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Two structurally related starch-binding domain families CBM25 and CBM26

(2014) Katarína Majzlová et al.   BIOLOGIA

Crystal structure of α-amylase fromOryza sativa: molecular insights into enzyme activity and thermostability

(2014) Akihito Ochiai et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Close relationship of a novel Flavobacteriaceae α-amylase with archaeal α-amylases and good potentials for industrial applications

(2014) Chunfang Li et al.   Biotechnology for Biofuels

A starch-binding domain identified in α-amylase (AmyP) represents a new family of carbohydrate-binding modules that contribute to enzymatic hydrolysis of soluble starch

(2014) Hui Peng et al.   FEBS LETTERS

Dimeric Quaternary Structure of Human Laforin

(2014) Rajeshwer S. Sankhala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insight in the structural features of haloadaptation in α-amylases from halophilic Archaea following homology modeling strategy: folded and stable conformation maintained through low hydrophobicity and highly negative charged surface

(2014) Mohamed Amine Zorgani et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

(2014) A. Rosell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A family of starch-active polysaccharide monooxygenases

(2014) V. V. Vu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystallization and preliminary X-ray crystallographic analysis of the amylomaltase fromCorynebacterium glutamicum

(2013) Wiraya Srisimarat et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Direct cloning of gene encoding a novel amylomaltase from soil bacterial DNA for large-ring cyclodextrin production

(2013) K. Sawasdee et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

α-Amylase: an enzyme specificity found in various families of glycoside hydrolases

(2013) Štefan Janeček et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Biochemical characterization of 4-α-glucanotransferase fromSaccharophagus degradans2-40 and its potential role in glycogen degradation

(2013) Sungmin Hwang et al.   FEMS MICROBIOLOGY LETTERS

A Bacterial Glucanotransferase Can Replace the Complex Maltose Metabolism Required for Starch to Sucrose Conversion in Leaves at Night

(2013) Christian Ruzanski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary History of Eukaryotic α-Glucosidases from the α-Amylase Family

(2013) Marek Gabriško   JOURNAL OF MOLECULAR EVOLUTION

Two potentially novel amylolytic enzyme specificities in the prokaryotic glycoside hydrolase  -amylase family GH57

(2013) K. Blesak et al.   MICROBIOLOGY-SGM

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Polysaccharide-synthesizing Glycosyltransferases and Carbohydrate Binding Modules: the case of Starch Synthase III

(2013) Diego Casati et al.   PROTEIN AND PEPTIDE LETTERS

Functional and structural studies of pullulanase fromAnoxybacillussp. LM18-11

(2013) Jianyong Xu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Analysis of the expression, subcellular and tissue localisation of phosphoglucan, water dikinase (PWD/GWD3) in Solanum tuberosum L.: a bioinformatics approach for the comparative analysis of two α-glucan, water dikinases (GWDs) from Solanum tuberosum L.

(2012) Slawomir Orzechowski et al.   ACTA PHYSIOLOGIAE PLANTARUM

Altered Large-Ring Cyclodextrin Product Profile Due to a Mutation at Tyr-172 in the Amylomaltase of Corynebacterium glutamicum

(2012) Wiraya Srisimarat et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Preferential and rapid degradation of raw rice starch by an α-amylase of glycoside hydrolase subfamily GH13_37

(2012) Yin Lei et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Starch modification with microbial alpha-glucanotransferase enzymes

(2012) Marc J.E.C. van der Maarel et al.   CARBOHYDRATE POLYMERS

Tracing the evolution of the α-amylase subfamily GH13_36 covering the amylolytic enzymes intermediate between oligo-1,6-glucosidases and neopullulanases

(2012) Katarína Majzlová et al.   CARBOHYDRATE RESEARCH

Sequence fingerprints of enzyme specificities from the glycoside hydrolase family GH57

(2012) Karol Blesák et al.   EXTREMOPHILES

Laforin, a protein with many faces: glucan phosphatase, adapter protein, et alii

(2012) Matthew S. Gentry et al.   FEBS Journal

The plastidial glucan, water dikinase (GWD) catalyses multiple phosphotransfer reactions

(2012) Mahdi Hejazi et al.   FEBS Journal

In silico identification of catalytic residues and domain fold of the family GH119 sharing the catalytic machinery with the α-amylase family GH57

(2012) Štefan Janeček et al.   FEBS LETTERS

Borrelia burgdorferi malQmutants utilize disaccharides and traverse the enzootic cycle

(2012) Laura L. Hoon-Hanks et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Raw starch-degrading α-amylase fromBacillus aquimarisMKSC 6.2: isolation and expression of the gene, bioinformatics and biochemical characterization of the recombinant enzyme

(2012) F. Puspasari et al.   JOURNAL OF APPLIED MICROBIOLOGY

Enzymology and Structure of the GH13_31 Glucan 1,6- -Glucosidase That Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus acidophilus NCFM

(2012) M. S. Moller et al.   JOURNAL OF BACTERIOLOGY

Multidomain Carbohydrate-binding Proteins Involved inBacteroides thetaiotaomicronStarch Metabolism

(2012) Elizabeth A. Cameron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4,6-α-Glucanotransferase, a Novel Enzyme That Structurally and Functionally Provides an Evolutionary Link between Glycoside Hydrolase Enzyme Families 13 and 70

(2011) Slavko Kralj et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Occurrence and functional significance of secondary carbohydrate binding sites in glycoside hydrolases

(2011) Sven Cuyvers et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Structural and evolutionary aspects of two families of non-catalytic domains present in starch and glycogen binding proteins from microbes, plants and animals

(2011) Štefan Janeček et al.   ENZYME AND MICROBIAL TECHNOLOGY

Starch-binding domains in the CBM45 family - low-affinity domains from glucan, water dikinase and α-amylase involved in plastidial starch metabolism

(2011) Mikkel A. Glaring et al.   FEBS Journal

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Sequence-Structural Features and Evolutionary Relationships of Family GH57 α-Amylases and Their Putative α-Amylase-Like Homologues

(2011) Štefan Janeček et al.   PROTEIN JOURNAL

Tyrosine 39 of GH13 α-amylase from Thermococcus hydrothermalis contributes to its thermostability

(2010) Andrej Godány et al.   BIOLOGIA

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism

(2010) Sixin Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel amylomaltase from Corynebacterium glutamicum and analysis of the large-ring cyclodextrin products

(2010) Wiraya Srisimarat et al.   JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

Pathophysiology and treatment of cystinuria

(2010) Josep Chillarón et al.   Nature Reviews Nephrology

Repression of both isoforms of disproportionating enzyme leads to higher malto-oligosaccharide content and reduced growth in potato

(2010) Henrik Lütken et al.   PLANTA

Structural basis for the glucan phosphatase activity of Starch Excess4

(2010) C. W. Vander Kooi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes

(2010) A. Vujicic-Zagar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Sequence, Bioinformatics and Enzymatic Characterization of α-Amylase from Saccharomycopsis fibuligera KZ

(2010) Eva Hostinová et al.   PROTEIN JOURNAL

Structural and functional analysis of substrate recognition by the 250s loop in amylomaltase from Thermus brockianus

(2010) Jong-Hyun Jung et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

SusG: A Unique Cell-Membrane-Associated α-Amylase from a Prominent Human Gut Symbiont Targets Complex Starch Molecules

(2010) Nicole M. Koropatkin et al.   STRUCTURE

Drosophilaexpresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties

(2009) Bruno Reynolds et al.   BIOCHEMICAL JOURNAL

Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 α-amylase family

(2009) Marek Gabriško et al.   FEBS Journal

The carbohydrate-binding module family 20 - diversity, structure, and function

(2009) Camilla Christiansen et al.   FEBS Journal

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Characterization of 4-α-glucanotransferase from Synechocystis sp. PCC 6803 and its application to various corn starches

(2009) Byung-Hoo Lee et al.   New Biotechnology

STARCH-EXCESS4 Is a Laforin-Like Phosphoglucan Phosphatase Required for Starch Degradation in Arabidopsis thaliana

(2009) O. Kotting et al.   PLANT CELL

Lafora disease: insights into neurodegeneration from plant metabolism

(2009) Matthew S. Gentry et al.   TRENDS IN BIOCHEMICAL SCIENCES

The unique glycoside hydrolase family 77 amylomaltase fromBorrelia burgdorferiwith only catalytic triad conserved

(2008) Andrej Godány et al.   FEMS MICROBIOLOGY LETTERS

Domain Characterization of a 4-α-Glucanotransferase Essential for Maltose Metabolism in Photosynthetic Leaves

(2008) Jon M. Steichen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing the Role of Aromatic Residues at the Secondary Saccharide-Binding Sites of Human Salivary α-Amylase in Substrate Hydrolysis and Bacterial Binding

(2008) Chandran Ragunath et al.   JOURNAL OF MOLECULAR BIOLOGY

Substrate Recognition Mechanism of α-1,6-Glucosidic Linkage Hydrolyzing Enzyme, Dextran Glucosidase from Streptococcus mutans

(2008) Hironori Hondoh et al.   JOURNAL OF MOLECULAR BIOLOGY

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of GH13 α-glucosidase GSJ from one of the deepest sea bacteria

(2008) Tsuyoshi Shirai et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS