Tunable and reversible drug control of protein production via a self-excising degron

A Dual Small-Molecule Rheostat for Precise Control of Protein Concentration in Mammalian Cells

(2014) Yu Hsuan Lin et al.   CHEMBIOCHEM

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impact of regulatory variation from RNA to protein

(2014) A. Battle et al.   SCIENCE

Oncolytic measles virus strains as novel anticancer agents

(2013) Pavlos Msaouel et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The Measles Virus Nucleocapsid Protein Tail Domain Is Dispensable for Viral Polymerase Recruitment and Activity

(2013) Stefanie A. Krumm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A rugged and accurate liquid chromatography–tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma

(2013) Long Yuan et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease

(2013) Yutong Jiang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Broadly Applicable Methodology for the Rapid and Dosable Small Molecule-Mediated Regulation of Transcription Factors in Human Cells

(2013) Matthew D. Shoulders et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Stabilized Headless Measles Virus Attachment Protein Stalk Efficiently Triggers Membrane Fusion

(2013) M. A. Brindley et al.   JOURNAL OF VIROLOGY

Variation and genetic control of protein abundance in humans

(2013) Linfeng Wu et al.   NATURE

New viruses for cancer therapy: meeting clinical needs

(2013) Tanner S. Miest et al.   NATURE REVIEWS MICROBIOLOGY

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032)

(2012) Fiona McPhee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of Hydrophobic Tags for the Degradation of Stabilized Proteins

(2012) Hyun Seop Tae et al.   CHEMBIOCHEM

Plasticity in Structural and Functional Interactions between the Phosphoprotein and Nucleoprotein of Measles Virus

(2012) Yaoling Shu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy

(2012) Margaret T Butko et al.   NATURE NEUROSCIENCE

Kinetic study of de novo chromophore maturation of fluorescent proteins

(2011) Ryo Iizuka et al.   ANALYTICAL BIOCHEMISTRY

Functional genetics in Apicomplexa: Potentials and limits

(2011) Julien Limenitakis et al.   FEBS LETTERS

Small-molecule displacement of a cryptic degron causes conditional protein degradation

(2011) Kimberly M Bonger et al.   Nature Chemical Biology

Vigilance and Validation: Keys to Success in RNAi Screening

(2010) Frederic D. Sigoillot et al.   ACS Chemical Biology

A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System

(2010) Mari Iwamoto et al.   CHEMISTRY & BIOLOGY

Enhanced Antitumor Effects of an Engineered Measles Virus Edmonston Strain Expressing the Wild-type N , P , L Genes on Human Renal Cell Carcinoma

(2010) Xin Meng et al.   MOLECULAR THERAPY

Poxvirus interleukin-4 expression overcomes inherent resistance and vaccine-induced immunity: Pathogenesis, prophylaxis, and antiviral therapy

(2010) Nanhai Chen et al.   VIROLOGY

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

(2009) L. J. Su et al.   Disease Models & Mechanisms

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded

(2008) Roberto Cattaneo et al.   NATURE REVIEWS MICROBIOLOGY

A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals

(2008) M. Z. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex

(2008) V. Brass et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis

(2008) M. Garas et al.   RNA