The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Assessing Kinetics from Fixed Cells Reveals Activation of the Mitotic Entry Network at the S/G2 Transition

(2014) Karen Akopyan et al.   MOLECULAR CELL

Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair

(2013) T. O. Auer et al.   GENOME RESEARCH

Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression

(2013) Peng Wang et al.   JOURNAL OF CELL BIOLOGY

Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A

(2013) Ricardo Nunes Bastos et al.   JOURNAL OF CELL BIOLOGY

The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation

(2013) Michael J. Cundell et al.   MOLECULAR CELL

Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals

(2013) M. Alvarez-Fernandez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond

(2013) Lidiya Luzhna et al.   Frontiers in Genetics

Cancer cell micronucleus: an update on clinical and diagnostic applications

(2012) Alka Bhatia et al.   APMIS

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

(2012) M. K. Diril et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KIF4 Regulates Midzone Length during Cytokinesis

(2011) Chi-Kuo Hu et al.   CURRENT BIOLOGY

The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

(2011) Anja K. Dunsch et al.   JOURNAL OF CELL BIOLOGY

Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited

(2011) Tamara A. Potapova et al.   MOLECULAR BIOLOGY OF THE CELL

A Minimal Midzone Protein Module Controls Formation and Length of Antiparallel Microtubule Overlaps

(2010) Peter Bieling et al.   CELL

Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein

(2010) Radhika Subramanian et al.   CELL

MASTL is the human ortholog of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis

(2010) Erik Voets et al.   CELL CYCLE

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

(2010) Amity L Manning et al.   EMBO JOURNAL

Aurora B kinase controls the targeting of the Astrin–SKAP complex to bioriented kinetochores

(2010) Jens C. Schmidt et al.   JOURNAL OF CELL BIOLOGY

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

Cyclin A2-Cyclin-Dependent Kinase 2 Cooperates with the PLK1-SCF -TrCP1-EMI1-Anaphase-Promoting Complex/Cyclosome Axis To Promote Genome Reduplication in the Absence of Mitosis

(2009) H. T. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis

(2008) Qiang Chen et al.   CELL RESEARCH

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

(2008) Alexander W. Bird et al.   JOURNAL OF CELL BIOLOGY

Survival of aneuploid, micronucleated and/or polyploid cells: Crosstalk between ploidy control and apoptosis

(2007) Ilse Decordier et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS