Wound healing across the animal kingdom: Crosstalk between the immune system and the extracellular matrix

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair

(2020) Filipa C. Simões et al.   Nature Communications

Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus

(2020) Jung Hae Yoon et al.   Scientific Reports

Blastemal progenitors modulate immune signaling during early limb regeneration

(2019) Stephanie L. Tsai et al.   DEVELOPMENT

CTHRC1 promotes wound repair by increasing M2 macrophages via regulating the TGF-β and notch pathways

(2019) Shu Qin et al.   BIOMEDICINE & PHARMACOTHERAPY

Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases

(2019) Oindrila Bhattacharjee et al.   Frontiers in Cell and Developmental Biology

Gene Expression Profiling of the Extracellular Matrix Signature in Macrophages of Different Activation Status: Relevance for Skin Wound Healing

(2019) Julia Etich et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fundamental aspects of arm repair phase in two echinoderm models

(2018) Cinzia Ferrario et al.   DEVELOPMENTAL BIOLOGY

Learning from regeneration research organisms: The circuitous road to scar free wound healing

(2018) Jami R. Erickson et al.   DEVELOPMENTAL BIOLOGY

A complex interplay between the extracellular matrix and the innate immune response to microbial pathogens

(2018) Hannah Tomlin et al.   IMMUNOLOGY

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

(2018) Mireya Plass et al.   SCIENCE

Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation

(2018) Timothy Q. DuBuc et al.   Nature Communications

The Cellular and Molecular Basis for Planarian Regeneration

(2018) Peter W. Reddien   CELL

foxF-1 Controls Specification of Non-body Wall Muscle and Phagocytic Cells in Planarians

(2018) M. Lucila Scimone et al.   CURRENT BIOLOGY

Insights into the regeneration of skin from Acomys , the spiny mouse

(2018) Malcolm Maden et al.   EXPERIMENTAL DERMATOLOGY

Identification and characterization of an atypical RIG-I encoded by planarian Dugesia japonica and its essential role in the immune response

(2018) Na Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Chasing the recipe for a pro-regenerative immune system

(2017) James W. Godwin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish

(2017) Daniel Wehner et al.   Nature Communications

Drosophila Embryonic Hemocytes Produce Laminins to Strengthen Migratory Response

(2017) Besaiz J. Sánchez-Sánchez et al.   Cell Reports

The sea cucumber genome provides insights into morphological evolution and visceral regeneration

(2017) Xiaojun Zhang et al.   PLOS BIOLOGY

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

(2017) Shih-Lei Lai et al.   eLife

Macrophages are necessary for epimorphic regeneration in African spiny mice

(2017) Jennifer Simkin et al.   eLife

Immunity in Protochordates: The Tunicate Perspective

(2017) Nicola Franchi et al.   Frontiers in Immunology

Genomics and development of Nematostella vectensis and other anthozoans

(2016) Fabian Rentzsch et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cellular events during scar-free skin regeneration in the spiny mouse,Acomys

(2016) Jason O. Brant et al.   WOUND REPAIR AND REGENERATION

Comparative analysis of ear-hole closure identifies epimorphic regeneration as a discrete trait in mammals

(2016) Thomas R. Gawriluk et al.   Nature Communications

The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration

(2016) Michael J. Layden et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing

(2016) Thomas S. Lisse et al.   Scientific Reports

Draper/CED-1 Mediates an Ancient Damage Response to Control Inflammatory Blood Cell Migration In Vivo

(2015) Iwan Robert Evans et al.   CURRENT BIOLOGY

Matrix metalloproteinase 9 modulates collagen matrices and wound repair

(2015) D. C. LeBert et al.   DEVELOPMENT

Drosophilablood cells and their role in immune responses

(2015) Isabella Vlisidou et al.   FEBS Journal

Cellular responses and HSP70 expression during wound healing in Holothuria tubulosa (Gmelin, 1788)

(2015) Mirella Vazzana et al.   FISH & SHELLFISH IMMUNOLOGY

Genetics on the Fly: A Primer on the Drosophila Model System

(2015) K. G. Hales et al.   GENETICS

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

Heat stress promotes extracellular matrix remodelling via TGF-β1 and MMP-2/TIMP-2 modulation in tenotomised soleus and plantaris muscles

(2015) Muthita Hirunsai et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation

(2015) J. Knuever et al.   JOURNAL OF IMMUNOLOGY

Ultrastructural aspects of naturally occurring wound in the tunic of two ascidians: Ciona intestinalis and Styela plicata (Tunicata)

(2015) Maria Antonietta Di Bella et al.   MICRON

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials-Science & Engineering

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials Science & Engineering

Fibrinogen-Related Proteins in Tissue Repair: How a Unique Domain with a Common Structure Controls Diverse Aspects of Wound Healing

(2015) Lorena Zuliani-Alvarez et al.   Advances in Wound Care

Cysteine cathepsins and extracellular matrix degradation

(2014) Marko Fonović et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Macrophages modulate adult zebrafish tail fin regeneration

(2014) T. A. Petrie et al.   DEVELOPMENT

Preliminary characterization of complement in a colonial tunicate: C3, Bf and inhibition of C3 opsonic activity by compstatin

(2014) Nicola Franchi et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Extracellular matrix considerations for scar-free repair and regeneration: Insights from regenerative diversity among vertebrates

(2014) James Godwin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Deer antler – A novel model for studying organ regeneration in mammals

(2014) Chunyi Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The tunicateCiona: a model system for understanding the relationship between regeneration and aging

(2014) William R. Jeffery   INVERTEBRATE REPRODUCTION & DEVELOPMENT

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Innate immune system and tissue regeneration in planarians: An area ripe for exploration

(2014) T. Harshani Peiris et al.   SEMINARS IN IMMUNOLOGY

Injury-induced immune responses in Hydra

(2014) Yvan Wenger et al.   SEMINARS IN IMMUNOLOGY

Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals

(2014) Kurt Buchmann   Frontiers in Immunology

Skin Wound Healing and Scarring: Fetal Wounds and Regenerative Restitution

(2013) Cecelia C. Yates et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Lens regeneration in axolotl: new evidence of developmental plasticity

(2013) Rinako Suetsugu-Maki et al.   BMC BIOLOGY

Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release

(2013) William Razzell et al.   CURRENT BIOLOGY

Skin wound healing in different agedXenopus laevis

(2013) Evelina Bertolotti et al.   JOURNAL OF MORPHOLOGY

Calpain A modulates Toll responses by limited Cactus/IκB proteolysis

(2013) Marcio Fontenele et al.   MOLECULAR BIOLOGY OF THE CELL

Macrophages are required for adult salamander limb regeneration

(2013) James W. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat Shock Proteins: Stimulators of Innate and Acquired Immunity

(2013) Camilo A. Colaco et al.   Biomed Research International

Immunosenescence in vertebrates and invertebrates

(2013) Ludmila Müller et al.   Immunity & Ageing

Evolution of Vertebrate Immunity

(2012) Thomas Boehm   CURRENT BIOLOGY

Fetal wound healing

(2012) Alice Leung et al.   CURRENT OPINION IN PEDIATRICS

An RNAi Screen Reveals Intestinal Regulators of Branching Morphogenesis, Differentiation, and Stem Cell Proliferation in Planarians

(2012) David J. Forsthoefel et al.   DEVELOPMENTAL CELL

Components, structure, biogenesis and function of the Hydra extracellular matrix in regeneration, pattern formation and cell differentiation

(2012) Michael P. Sarras (Jr)   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

(2012) Sa Kan Yoo et al.   JOURNAL OF CELL BIOLOGY

Skin shedding and tissue regeneration in African spiny mice (Acomys)

(2012) Ashley W. Seifert et al.   NATURE

Skin Regeneration in Adult Axolotls: A Blueprint for Scar-Free Healing in Vertebrates

(2012) Ashley W. Seifert et al.   PLoS One

Genome streamlining and chemical defense in a coral reef symbiosis

(2012) J. C. Kwan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlating structure and function during the evolution of fibrinogen-related domains

(2012) Russell F. Doolittle et al.   PROTEIN SCIENCE

Regeneration: The ultimate example of wound healing

(2012) Prayag Murawala et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Gαq-Ca2+ Signaling Pathway Promotes Actin-Mediated Epidermal Wound Closure in C. elegans

(2011) Suhong Xu et al.   CURRENT BIOLOGY

Innate immune response in the hemolymph of an ascidian, Halocynthia roretzi, showing soft tunic syndrome, using label-free quantitative proteomics

(2011) In Seok Cha et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Swatting flies: modelling wound healing and inflammation in Drosophila

(2011) W. Razzell et al.   Disease Models & Mechanisms

A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome

(2011) Alessandro Ori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prx-1 Expression in Xenopus laevis Scarless Skin-Wound Healing and Its Resemblance to Epimorphic Regeneration

(2011) Hitoshi Yokoyama et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Cross Talk among TGF-  Signaling Pathways, Integrins, and the Extracellular Matrix

(2011) J. S. Munger et al.   Cold Spring Harbor Perspectives in Biology

Regenerative capacity in newts is not altered by repeated regeneration and ageing

(2011) Goro Eguchi et al.   Nature Communications

The head-regeneration transcriptome of the planarian Schmidtea mediterranea

(2011) Thomas Sandmann et al.   GENOME BIOLOGY

Prioritization of Competing Damage and Developmental Signals by Migrating Macrophages in the Drosophila Embryo

(2010) Severina Moreira et al.   CURRENT BIOLOGY

A transitional extracellular matrix instructs cell behavior during muscle regeneration

(2010) Sarah Calve et al.   DEVELOPMENTAL BIOLOGY

Matrix metalloproteinase expression during blastema formation in regeneration-competent versus regeneration-deficient amphibian limbs

(2010) Neetha Santosh et al.   DEVELOPMENTAL DYNAMICS

Differential Roles of Macrophages in Diverse Phases of Skin Repair

(2010) T. Lucas et al.   JOURNAL OF IMMUNOLOGY

The dynamic genome of Hydra

(2010) Jarrod A. Chapman et al.   NATURE

Platelet receptors and signaling in the dynamics of thrombus formation

(2009) J. Rivera et al.   HAEMATOLOGICA

Signaling Pathways Implicated in the Stimulation of β-Cell Proliferation by Extracellular Matrix

(2009) Géraldine Parnaud et al.   MOLECULAR ENDOCRINOLOGY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Assessing the root of bilaterian animals with scalable phylogenomic methods

(2009) A. Hejnol et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Comparative Aspects of Animal Regeneration

(2008) Jeremy P. Brockes et al.   Annual Review of Cell and Developmental Biology

Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence

(2008) Thomas C.G. Bosch et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Induced cell proliferation in putative haematopoietic tissues of the sea star, Asterias rubens (L.)

(2008) K. Holm et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The extracellular matrix of hydra is a porous sheet and contains type IV collagen

(2008) Hiroshi Shimizu et al.   ZOOLOGY