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Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis

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A Highly Durable RNAi Therapeutic Inhibitor of PCSK9

(2017) Kevin Fitzgerald et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol

(2017) Kausik K. Ray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant?

(2017) Zhongji Meng et al.   Frontiers in Immunology

Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia

(2017) Sabine Sewing et al.   PLoS One

From guide to target: molecular insights into eukaryotic RNA-interference machinery

(2015) Jonathan J Ipsaro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

From guide to target: molecular insights into eukaryotic RNA-interference machinery

(2015) Jonathan J Ipsaro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

(2014) A. Forsbach et al.   JOURNAL OF IMMUNOLOGY

Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

(2014) Jayaprakash K. Nair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering

(2012) Jesper B. Bramsen et al.   Frontiers in Genetics

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY