Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions

Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

(2019) Marlijn van der Poel et al.   Nature Communications

Post‐mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms

(2019) Nina L. Fransen et al.   BRAIN PATHOLOGY

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice

(2019) Karin Steinbach et al.   Science Translational Medicine

PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis

(2019) Shwetank et al.   Frontiers in Immunology

Communication of CD 8 + T cells with mononuclear phagocytes in multiple sclerosis

(2019) Matea Konjevic Sabolek et al.   Annals of Clinical and Translational Neurology

Location, location, location: Tissue resident memory T cells in mice and humans

(2019) Peter A. Szabo et al.   Science Immunology

Myelin-specific CD8+ T cells exacerbate brain inflammation in CNS autoimmunity

(2019) Catriona A. Wagner et al.   JOURNAL OF CLINICAL INVESTIGATION

Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis

(2018) Sabina Luchetti et al.   ACTA NEUROPATHOLOGICA

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells

(2018) Joana Machado-Santos et al.   BRAIN

The roles of resident, central and effector memory CD4 T-cells in protective immunity following infection or vaccination

(2018) Joshua I. Gray et al.   IMMUNOLOGY

Dynamics of Tissue-Specific CD8+ T Cell Responses during West Nile Virus Infection

(2018) Renan Aguilar-Valenzuela et al.   JOURNAL OF VIROLOGY

Multiple sclerosis

(2018) Alan J Thompson et al.   LANCET

Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study

(2018) Mario Merlini et al.   Neurodegenerative Diseases

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

(2018) David J. Topham et al.   Frontiers in Immunology

Tissue-resident memory T cells populate the human brain

(2018) Joost Smolders et al.   Nature Communications

Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types

(2017) Vincent van Unen et al.   Nature Communications

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions

(2017) Debbie A. E. Hendrickx et al.   Frontiers in Immunology

Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables

(2017) Mark R. Mizee et al.   Acta Neuropathologica Communications

MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer’s disease

(2016) Qiong-Bin Zhu et al.   BRAIN

The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain

(2016) Lukas Haider et al.   BRAIN

Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer’s Disease?

(2016) Antoine Louveau et al.   NEURON

Disease modifying therapies for relapsing multiple sclerosis

(2016) Dean M Wingerchuk et al.   BMJ-British Medical Journal

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

(2016) Gin-Wen Chang et al.   Cell Reports

Disease modifying therapies for relapsing multiple sclerosis

(2016) Dean M Wingerchuk et al.   BMJ-British Medical Journal

Ectopic Lymphoid Structures: Powerhouse of Autoimmunity

(2016) Elisa Corsiero et al.   Frontiers in Immunology

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Subacute CNS Demyelination after Treatment with Nivolumab for Melanoma

(2015) C. Maurice et al.   Cancer Immunology Research

Characteristics of differentiated CD8+ and CD4+ T cells present in the human brain

(2013) Joost Smolders et al.   ACTA NEUROPATHOLOGICA

Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization

(2013) Elina Zotova et al.   BRAIN

Selective Upregulation of Scavenger Receptors in and Around Demyelinating Areas in Multiple Sclerosis

(2013) Debbie A.E. Hendrickx et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions

(2013) Corinne Brana et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis

(2012) Kathrine E. Attfield et al.   IMMUNOLOGICAL REVIEWS

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

GRK2-Dependent S1PR1 Desensitization Is Required for Lymphocytes to Overcome Their Attraction to Blood

(2011) T. I. Arnon et al.   SCIENCE

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

(2010) Ruben Van Doorn et al.   GLIA

Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation

(2010) Andreia Soares et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

(2010) L. M. Wakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN