Myelin-specific CD8+ T cells exacerbate brain inflammation in CNS autoimmunity

The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models

(2019) Benjamin Segal   Journal of Clinical Medicine

Opposing T cell responses in experimental autoimmune encephalomyelitis

(2019) Naresha Saligrama et al.   NATURE

Beyond Cell Death: New Functions for TNF Family Cytokines in Autoimmunity and Tumor Immunotherapy

(2018) Fei Yi et al.   TRENDS IN MOLECULAR MEDICINE

Multiple sclerosis

(2018) Massimo Filippi et al.   Nature Reviews Disease Primers

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Anti-inflammatory mechanisms of IFN-γ studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis

(2015) Nichole M. Miller et al.   Frontiers in Neuroscience

CD8+ T-Cells as Immune Regulators of Multiple Sclerosis

(2015) Sushmita Sinha et al.   Frontiers in Immunology

Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells

(2014) Khrishen Cunnusamy et al.   CLINICAL IMMUNOLOGY

Relapsing-Remitting Central Nervous System Autoimmunity Mediated by GFAP-Specific CD8 T Cells

(2014) K. Sasaki et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Regulated Neutrophil Recruitment Is Required for Brain but Not Spinal Cord Inflammation during Experimental Autoimmune Encephalomyelitis

(2014) Sarah B. Simmons et al.   JOURNAL OF IMMUNOLOGY

MHC class I–restricted myelin epitopes are cross-presented by Tip-DCs that promote determinant spreading to CD8+ T cells

(2013) Qingyong Ji et al.   NATURE IMMUNOLOGY

Modeling the heterogeneity of multiple sclerosis in animals

(2013) Sarah B. Simmons et al.   TRENDS IN IMMUNOLOGY

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Frequency of circulating autoreactive T cells committed to myelin determinants in relapsing–remitting multiple sclerosis patients

(2012) Annie Elong Ngono et al.   CLINICAL IMMUNOLOGY

A Transgenic Model of Central Nervous System Autoimmunity Mediated by CD4+ and CD8+ T and B Cells

(2012) A. C. Anderson et al.   JOURNAL OF IMMUNOLOGY

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis

(2011) Ethan J. Baughman et al.   JOURNAL OF AUTOIMMUNITY

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models

(2010) Lennart T. Mars et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs

(2010) Qingyong Ji et al.   NATURE IMMUNOLOGY

A new function of the Fas-FasL pathway in macrophage activation

(2009) Reza Chakour et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

(2008) Manuel A Friese et al.   NATURE MEDICINE