Designing a new dimerized anti human TNF‐α aptamer with blocking activity

Recent Advances in Aptamer Discovery and Applications

(2019) Yang Zhang et al.   MOLECULES

Gradual tapering TNF inhibitors versus conventional synthetic DMARDs after achieving controlled disease in patients with rheumatoid arthritis: first-year results of the randomised controlled TARA study

(2019) Elise van Mulligen et al.   ANNALS OF THE RHEUMATIC DISEASES

Tumour Necrosis Factor Alpha in Intestinal Homeostasis and Gut Related Diseases

(2019) Barbara Ruder et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

V617F‐independent upregulation of JAK2 gene expression in patients with inflammatory bowel disease

(2019) Hamid Asadzadeh‐Aghdaei et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inside the Black Box: What Makes SELEX Better?

(2019) Natalia Komarova et al.   MOLECULES

Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application

(2019) Adachi et al.   MOLECULES

Effectiveness and safety of anti-TNF therapy for inflammatory bowel disease in liver transplant recipients for primary sclerosing cholangitis: A nationwide case series

(2018) Romain Altwegg et al.   DIGESTIVE AND LIVER DISEASE

Structural Biology of the TNFα Antagonists Used in the Treatment of Rheumatoid Arthritis

(2018) Heejin Lim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AS1411 aptamer conjugated gold nanoclusters as a targeted radiosensitizer for megavoltage radiation therapy of 4T1 breast cancer cells

(2018) Fatemeh Ghahremani et al.   RSC Advances

Safety and tolerability of adalimumab for the treatment of psoriasis: a review summarizing 15 years of real-life experience

(2018) Paul Sator   Therapeutic Advances in Chronic Disease

Development of Cell-Specific Aptamers: Recent Advances and Insight into the Selection Procedures

(2017) Kamal Rahimizadeh et al.   MOLECULES

PLGA nanoparticles with CD133 aptamers for targeted delivery and sustained release of propranolol to hemangioma

(2017) Xiaonan Guo et al.   Nanomedicine

DNA aptamer probes for detection of estrogen receptor α positive carcinomas

(2017) Arghya Sett et al.   Translational Research

Selection, characterization, and application of DNA aptamers for detection of Mycobacterium tuberculosis secreted protein MPT64

(2017) Marzhan Sypabekova et al.   TUBERCULOSIS

A Novel PEGylation Method for Improving the Pharmacokinetic Properties of Anti-Interleukin-17A RNA Aptamers

(2017) Kazuhiko Haruta et al.   Nucleic Acid Therapeutics

Cell-SELEX-based selection and characterization of a G-quadruplex DNA aptamer against mouse dendritic cells

(2016) M. Moghadam et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Methods for Improving Aptamer Binding Affinity

(2016) Hijiri Hasegawa et al.   MOLECULES

Screening and identification of DNA aptamers toward Schistosoma japonicum eggs via SELEX

(2016) Yuqian Long et al.   Scientific Reports

Selection of LNA-containing DNA aptamers against recombinant human CD73

(2015) Ida C. Elle et al.   Molecular BioSystems

Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers

(2015) Aaron Prodeus et al.   Molecular Therapy-Nucleic Acids

Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis: a systematic review and economic evaluation

(2014) M Rodgers et al.   HEALTH TECHNOLOGY ASSESSMENT

Optimization of SELEX: Comparison of different methods for monitoring the progress of in vitro selection of aptamers

(2014) Nina Mencin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Agonistic CD200R1 DNA Aptamers Are Potent Immunosuppressants That Prolong Allogeneic Skin Graft Survival

(2014) Aaron Prodeus et al.   Molecular Therapy-Nucleic Acids

Comparison of the Inhibition Mechanisms of Adalimumab and Infliximab in Treating Tumor Necrosis Factor α-Associated Diseases from a Molecular View

(2013) Shi Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Short DNA Aptamer That Recognizes TNFα and Blocks Its Activity in Vitro

(2012) Erik W. Orava et al.   ACS Chemical Biology

Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralising agents in chronic inflammatory diseases: a real issue, a clinical perspective

(2012) Fabien B Vincent et al.   ANNALS OF THE RHEUMATIC DISEASES

Aptamers and Their Biological Applications

(2012) Kyung-Mi Song et al.   SENSORS

In Vitro and Ex Vivo Selection Procedures for Identifying Potentially Therapeutic DNA and RNA Molecules

(2010) Soledad Marton et al.   MOLECULES

Screening and Improvement of an Anti-VEGF DNA Aptamer

(2010) Yoshihiko Nonaka et al.   MOLECULES

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Conditions optimized for the preparation of single-stranded DNA (ssDNA) employing lambda exonuclease digestion in generating DNA aptamer

(2010) Marimuthu Citartan et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Anti-TNF therapies: a comprehensive analysis of adverse effects associated with immunosuppression

(2009) Victoria Connor   RHEUMATOLOGY INTERNATIONAL

Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review

(2009) Andrea Rubbert-Roth et al.   ARTHRITIS RESEARCH & THERAPY

Mechanisms for cytotoxic effects of anti–tumor necrosis factor agents on transmembrane tumor necrosis factor α–expressing cells: Comparison among infliximab, etanercept, and adalimumab

(2008) Hiroki Mitoma et al.   ARTHRITIS AND RHEUMATISM

Improvement of Aptamer Affinity by Dimerization

(2008) Hijiri Hasegawa et al.   SENSORS

Anti-TNF agents for rheumatoid arthritis

(2003) H. E. Seymour et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY