Tanshinone II A enhances pyroptosis and represses cell proliferation of HeLa cells by regulating miR-145/GSDMD signaling pathway

MiR‐145 inhibits the migration and invasion of papillary thyroid carcinoma cells through NF‐κB pathway regulation

(2020) Gengyu Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Exosomal miR-106b serves as a novel marker for lung cancer and promotes cancer metastasis via targeting PTEN

(2020) Shifang Sun et al.   LIFE SCIENCES

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

(2020) Jin-Feng Teng et al.   Cancers

Natural killer T cell cytotoxic activity in cervical cancer is facilitated by the LINC00240/microRNA-124-3p/STAT3/MICA axis

(2020) Yan Zhang et al.   CANCER LETTERS

MiR-145 negatively regulates TGFBR2 signaling responsible for sepsis-induced acute lung injury

(2019) Xiaohua Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study

(2019) Hyun Cheol Chung et al.   JOURNAL OF CLINICAL ONCOLOGY

α-NETA induces pyroptosis of epithelial ovarian cancer cells through the GSDMD/caspase-4 pathway

(2019) Lianqiao Qiao et al.   FASEB JOURNAL

GSDMD is required for effector CD8+ T cell responses to lung cancer cells

(2019) Guangmin Xi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tanshinone IIA mediates SMAD7-YAP interaction to inhibit liver cancer growth by inactivating the transforming growth factor beta signaling pathway

(2019) Lifang Ma et al.   Aging-US

miR‐145 promotes miR‐133b expression through c‐myc and DNMT3A‐mediated methylation in ovarian cancer cells

(2019) Jie Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mode of action of carboplatin via activating p53/miR‐145 axis in head and neck cancers

(2019) Ahsen Kilic et al.   LARYNGOSCOPE

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

(2019) Dan A. Erkes et al.   Cancer Discovery

DNMT1 recruited by EZH2-mediated silencing of miR-484 contributes to the malignancy of cervical cancer cells through MMP14 and HNF1A

(2019) Yang Hu et al.   Clinical Epigenetics

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice

(2018) Bing Xu et al.   JOURNAL OF HEPATOLOGY

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

(2018) Darren C. Johnson et al.   NATURE MEDICINE

Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense

(2018) Daeho So et al.   ONCOGENE

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Downregulation of miR‐145‐5p contributes to hyperproliferation of keratinocytes and skin inflammation in psoriasis

(2018) J.J. Yan et al.   BRITISH JOURNAL OF DERMATOLOGY

Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling

(2018) Zhen Gong et al.   CELLULAR IMMUNOLOGY

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Management of patients with recurrent/advanced cervical cancer beyond first line platinum regimens: Where do we stand? A literature review

(2016) Stergios Boussios et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer

(2015) Radha Munagala et al.   CANCER LETTERS

Tanshinone II A Inhibits Tat-Induced HIV-1 Transactivation Through Redox-Regulated AMPK/Nampt Pathway

(2014) Hong-Sheng Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tanshinone derivatives: a patent review (January 2006 – September 2012)

(2012) Xiao-Hong Tian et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in Apolipoprotein-E knockout mice fed a high cholesterol diet

(2011) Suowen Xu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS

(2009) Guan-Wei Fan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Reducing Uncertainties About the Effects of Chemoradiotherapy for Cervical Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 18 Randomized Trials

(2008)   JOURNAL OF CLINICAL ONCOLOGY