Tanshinone II A Inhibits Tat-Induced HIV-1 Transactivation Through Redox-Regulated AMPK/Nampt Pathway

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Poly(ADP-ribose) polymerase-1-induced NAD+ depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation

(2013) Tiina M. Kauppinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Blocking HIV-1 Replication by Targeting the Tat-Hijacked Transcriptional Machinery

(2013) Serena Massari et al.   CURRENT PHARMACEUTICAL DESIGN

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology

(2012) Tuva B. Dahl et al.   Annual Review of Nutrition

Tanshinone IIA improves endoplasmic reticulum stress-induced insulin resistance through AMP-activated protein kinase

(2012) Seung-Lark Hwang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

(2012) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Control of HIV Latency by Epigenetic and Non-Epigenetic Mechanisms

(2012) Jonathan Karn et al.   CURRENT HIV RESEARCH

Tanshinone derivatives: a patent review (January 2006 – September 2012)

(2012) Xiao-Hong Tian et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Tanshinone II-A: new perspectives for old remedies

(2012) Suowen Xu et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Seven sirtuins for seven deadly diseases ofaging

(2012) Brian J. Morris   FREE RADICAL BIOLOGY AND MEDICINE

Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

(2012) Xin-Yu Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hydrogen peroxide-mediated oxidative stress and collagen synthesis in cardiac fibroblasts: Blockade by tanshinone IIA

(2012) Ping Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Transcriptional Control of HIV Replication by Multiple Modulators and Their Implication for a Novel Antiviral Therapy

(2011) Ann Florence B. Victoriano et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

The Control of HIV Transcription: Keeping RNA Polymerase II on Track

(2011) Melanie Ott et al.   Cell Host & Microbe

NAMPT in Regulated NAD Biosynthesis and its Pivotal Role in Human Metabolism

(2011) E S. Burgos   CURRENT MEDICINAL CHEMISTRY

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

(2011) Shin-ichiro Imai   FEBS LETTERS

HDAC inhibitors in HIV

(2011) Fiona Wightman et al.   IMMUNOLOGY AND CELL BIOLOGY

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Shay Matalon et al.   MOLECULAR MEDICINE

Epigenetic regulation of HIV-1 transcription

(2011) Manoj Kumar Tripathy et al.   Epigenomics

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

(2010) Hong-Sheng Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Review: NAD + : A modulator of immune functions

(2010) Andreas Grahnert et al.   Innate Immunity

Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation

(2010) Hong-Sheng Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise

(2010) Brandon S. Razooky et al.   METHODS

Transcriptome analysis of monocyte-HIV interactions

(2010) Rafael Van den Bergh et al.   Retrovirology

Research Highlights

(2010) Jiri Hejnar et al.   Epigenomics

The Nicotinamide Phosphoribosyltransferase: A Molecular Link between Metabolism, Inflammation, and Cancer

(2009) M. Galli et al.   CANCER RESEARCH

Nrf2 is involved in inhibiting Tat-induced HIV-1 long terminal repeat transactivation

(2009) Hong-Sheng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol inhibited Tat-induced HIV-1 LTR transactivation via NAD+-dependent SIRT1 activity

(2009) Hong-Sheng Zhang et al.   LIFE SCIENCES

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

(2009) Frédéric Van Gool et al.   NATURE MEDICINE

Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

(2009) Santina Bruzzone et al.   PLoS One

SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase

(2009) Hong-Sheng Zhang et al.   VIRUS RESEARCH

Human Immunodeficiency Virus Type 1 Tat Protein Inhibits the SIRT1 Deacetylase and Induces T Cell Hyperactivation

(2008) Hye-Sook Kwon et al.   Cell Host & Microbe