The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis

Statin Toxicity

(2019) Natalie C. Ward et al.   CIRCULATION RESEARCH

Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells

(2019) Magda R Hamczyk et al.   EMBO Molecular Medicine

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

(2019) Robert C. Wirka et al.   NATURE MEDICINE

Vascular smooth muscle cells in atherosclerosis

(2019) Gemma L. Basatemur et al.   Nature Reviews Cardiology

Smooth muscle cell fate and plasticity in atherosclerosis

(2018) Sima Allahverdian et al.   CARDIOVASCULAR RESEARCH

Chloroquine improves the response to ischemic muscle injury and increases HMGB1 after arterial ligation

(2018) Jun Xu et al.   JOURNAL OF VASCULAR SURGERY

Evolving targets for the treatment of atherosclerosis

(2018) Ankita Solanki et al.   PHARMACOLOGY & THERAPEUTICS

Galectins Control MTOR and AMPK in Response to Lysosomal Damage to Induce Autophagy

(2018) Jingyue Jia et al.   Autophagy

The role of P2Y12 receptor in ischemic stroke of atherosclerotic origin

(2018) Ying Gao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Semaphorin-3A protects against neointimal hyperplasia after vascular injury

(2018) Jie-hong Wu et al.   EBioMedicine

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway

(2017) Yichi Yu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Efficacy and safety of ticagrelor versus aspirin in acute stroke or transient ischaemic attack of atherosclerotic origin: a subgroup analysis of SOCRATES, a randomised, double-blind, controlled trial

(2017) Pierre Amarenco et al.   LANCET NEUROLOGY

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

(2017) Kuan-lin Huang et al.   Nature Communications

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver

(2016) Nuria Martinez-Lopez et al.   Cell Metabolism

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic LesionsNovelty and Significance

(2016) Suzanne M. Eken et al.   CIRCULATION RESEARCH

Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease

(2016) William Herrington et al.   CIRCULATION RESEARCH

NG2 Ablation Reduces Low-Density Lipoprotein Retention of Synthetic Smooth Muscle Cells and Atherogenesis

(2015) Zhi-Gang She et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Purinergic Receptors in Thrombosis and Inflammation

(2015) Béatrice Hechler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

(2015) Ksenya Shchors et al.   CANCER CELL

Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis RegressionNovelty and Significance

(2015) Emil D. Bartels et al.   CIRCULATION RESEARCH

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Vessel wall, not platelet, P2Y12 potentiates early atherogenesis

(2014) L. E. West et al.   CARDIOVASCULAR RESEARCH

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Mechanisms That Regulate Macrophage Burden in Atherosclerosis

(2014) Gwendalyn J Randolph   CIRCULATION RESEARCH

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

CXCL5 limits macrophage foam cell formation in atherosclerosis

(2013) Anthony Rousselle et al.   JOURNAL OF CLINICAL INVESTIGATION

Wip1-Dependent Regulation of Autophagy, Obesity, and Atherosclerosis

(2012) Xavier Le Guezennec et al.   Cell Metabolism

Loss of autophagy in hypothalamic POMC neurons impairs lipolysis

(2012) Susmita Kaushik et al.   EMBO REPORTS

P2Y12 receptors in platelets and other hematopoietic and non-hematopoietic cells

(2012) Christian Gachet   Purinergic Signalling

Comparison of Differential Expression of P2Y12 Receptor in Culprit Coronary Plaques in Patients With Acute Myocardial Infarction Versus Stable Angina Pectoris

(2011) Cheol Whan Lee et al.   AMERICAN JOURNAL OF CARDIOLOGY

Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells

(2011) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Vitamin D Deficiency Is Associated With Subclinical Carotid Atherosclerosis

(2011) Angela L. Carrelli et al.   STROKE

Regulation of Functionally Active P2Y12 ADP Receptors by Thrombin in Human Smooth Muscle Cells and the Presence of P2Y12 in Carotid Artery Lesions

(2010) Bernhard H. Rauch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Novel Role of the CXC Chemokine Receptor 3 in Inflammatory Response to Arterial Injury

(2008) Johannes B.K. Schwarz et al.   CIRCULATION RESEARCH

Carotid plaque, a subclinical precursor of vascular events: The Northern Manhattan Study

(2008) T. Rundek et al.   NEUROLOGY