Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines

In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes

(2019) Georg Tascher et al.   Cells

Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay

(2019) Ji-Eun Seo et al.   ARCHIVES OF TOXICOLOGY

Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay

(2019) Marion Mandon et al.   Scientific Reports

Genetic toxicity assessment using liver cell models: past, present, and future

(2019) Xiaoqing Guo et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Assessment of the predictive capacity of the optimized in vitro comet assay using HepG2 cells

(2018) Yoon-hee Hong et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells

(2018) Xiaoqing Guo et al.   TOXICOLOGICAL SCIENCES

Use of human derived liver cells for the detection of genotoxins in comet assays

(2018) Miroslav Mišík et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comparing BMD-derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay

(2017) John W. Wills et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop

(2017) Gudrun Koppen et al.   MUTAGENESIS

Cell sources for in vitro human liver cell culture models

(2016) Katrin Zeilinger et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Quantitative analysis of the relative mutagenicity of five chemical constituents of tobacco smoke in the mouse lymphoma assay

(2015) Xiaoqing Guo et al.   MUTAGENESIS

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

(2015) Yoshifumi Uno et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

(2015) Günter Speit et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Performance of Comet and Micronucleus Assays in Metabolic Competent HepaRG Cells to Predict In Vivo Genotoxicity

(2014) Ludovic Le Hégarat et al.   TOXICOLOGICAL SCIENCES

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

(2012) H. H. J. Gerets et al.   CELL BIOLOGY AND TOXICOLOGY

Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test

(2011) Damian E. Bowen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells

(2009) S. Antherieu et al.   DRUG METABOLISM AND DISPOSITION

An in vivo comet assay of multiple organs (liver, kidney and bone marrow) in mice treated with methyl methanesulfonate and acetaminophen accompanied by hematology and/or blood chemistry

(2008) Keiyu Oshida et al.   JOURNAL OF TOXICOLOGICAL SCIENCES