Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

(2019) Jianying Han et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Potential of marine natural products against drug-resistant bacterial infections

(2019) Miaomiao Liu et al.   LANCET INFECTIOUS DISEASES

Sekgranaticin, a SEK34b-Granaticin Hybrid Polyketide from Streptomyces sp. 166#

(2019) Qianqian Lv et al.   JOURNAL OF ORGANIC CHEMISTRY

Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

(2019) Eachan O. Johnson et al.   NATURE

Absolute Configuration and Biological Activities of Meroterpenoids from an Endophytic Fungus of Lycium barbarum

(2019) Yi Long et al.   JOURNAL OF NATURAL PRODUCTS

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces

(2019) Weishan Wang et al.   NATURE BIOTECHNOLOGY

Genome Mining and Comparative Biosynthesis of Meroterpenoids from Two Phylogenetically Distinct Fungi

(2018) Xuan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic antifungal indolecarbazoles from Streptomyces sp. CNS-42 associated with traditional Chinese medicine Alisma orientale

(2017) Mei Liu et al.   JOURNAL OF ANTIBIOTICS

Actinomycete Metabolome Induction/Suppression with N-Acetylglucosamine

(2017) Yousef Dashti et al.   JOURNAL OF NATURAL PRODUCTS

Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp. MS100047

(2016) Pei Huang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity

(2016) Wenni He et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cytotoxic cochlioquinone derivatives from the endophytic fungus Bipolaris sorokiniana derived from Pogostemon cablin

(2016) Mo Wang et al.   FITOTERAPIA

Biosynthesis of fungal meroterpenoids

(2016) Yudai Matsuda et al.   NATURAL PRODUCT REPORTS

Meroterpenoids with Antiproliferative Activity from a Hawaiian-Plant Associated Fungus Peyronellaea coffeae-arabicae FT238

(2016) Chun-Shun Li et al.   ORGANIC LETTERS

Noncyanogenic Cyanoglucoside Cyclooxygenase Inhibitors from Simmondsia chinensis

(2016) Wael M. Abdel-Mageed et al.   ORGANIC LETTERS

Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

(2015) Wupeng Yan et al.   NATURE

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products inStreptomyces

(2015) Chaoxian Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methicillin-Resistant Staphylococcus aureus: An Evolving Pathogen

(2013) M. E. Stryjewski et al.   CLINICAL INFECTIOUS DISEASES

Caesanines A–D, New Cassane Diterpenes with Unprecedented N Bridge from Caesalpinia sappan

(2013) Jingyu Zhang et al.   ORGANIC LETTERS

Reconstituted biosynthesis of fungal meroterpenoid andrastin A

(2013) Yudai Matsuda et al.   TETRAHEDRON

Abyssomicins from the South China Sea Deep-Sea SedimentVerrucosisporasp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs

(2012) Qian Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

(2012) Yit-Heng Chooi et al.   JOURNAL OF ORGANIC CHEMISTRY

Quinazolin-4-one Coupled with Pyrrolidin-2-iminium Alkaloids from Marine-Derived Fungus Penicillium aurantiogriseum

(2012) Fuhang Song et al.   Marine Drugs

The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

(2011) David H. Kwan et al.   MOLECULES

Mutagenesis of a Modular Polyketide Synthase Enoylreductase Domain Reveals Insights into Catalysis and Stereospecificity

(2010) David H. Kwan et al.   ACS Chemical Biology

Antituberculosis Agents and an Inhibitor of the para-Aminobenzoic Acid Biosynthetic Pathway from Hydnocarpus anthelminthica Seeds

(2010) Jun-Feng Wang et al.   CHEMISTRY & BIODIVERSITY

Assigning Stereochemistry to Single Diastereoisomers by GIAO NMR Calculation: The DP4 Probability

(2010) Steven G. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases

(2010) Takayuki Itoh et al.   Nature Chemistry

Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

(2010) Y. Zhuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meroterpenoids produced by fungi

(2009) Regina Geris et al.   NATURAL PRODUCT REPORTS

Prediction and Manipulation of the Stereochemistry of Enoylreduction in Modular Polyketide Synthases

(2008) David H. Kwan et al.   CHEMISTRY & BIOLOGY

NCBI BLAST: a better web interface

(2008) M. Johnson et al.   NUCLEIC ACIDS RESEARCH

Leishmanicidal Metabolites from Cochliobolus sp., an Endophytic Fungus Isolated from Piptadenia adiantoides (Fabaceae)

(2008) Fernanda Fraga Campos et al.   PLoS Neglected Tropical Diseases