Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I andN-hydroxyaristolactam I in human cells

Bioactivation of the human carcinogen aristolochic acid

(2014) Viktoriya S. Sidorenko et al.   CARCINOGENESIS

Total Synthesis of the Aristolochic Acids, Their Major Metabolites, and Related Compounds

(2014) Sivaprasad Attaluri et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

(2014) Lukas Vaclavik et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Cd2+-Induced Alteration of the Global Proteome of Human Skin Fibroblast Cells

(2014) John M. Prins et al.   JOURNAL OF PROTEOME RESEARCH

The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats

(2014) Marie Stiborová et al.   MUTAGENESIS

Variation in genomic landscape of clear cell renal cell carcinoma across Europe

(2014) Ghislaine Scelo et al.   Nature Communications

Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer

(2013) Marie Stiborova et al.   CURRENT DRUG METABOLISM

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

(2013) S. L. Poon et al.   Science Translational Medicine

Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

(2013) M. L. Hoang et al.   Science Translational Medicine

Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease

(2012) Arthur P. Grollman   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy

(2012) Marc E. De Broe   KIDNEY INTERNATIONAL

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases

(2011) Marie Stiborová et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

(2011) Bojan Jelaković et al.   KIDNEY INTERNATIONAL

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

(2011) Victoria S. Sidorenko et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Renal NQO1 Activity by Dicoumarol Suppresses Nitroreduction of Aristolochic Acid I and Attenuates its Nephrotoxicity

(2011) Min Chen et al.   TOXICOLOGICAL SCIENCES

Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the Mouse

(2010) T. A. Rosenquist et al.   DRUG METABOLISM AND DISPOSITION

Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie"

(2009) Z. Riches et al.   DRUG METABOLISM AND DISPOSITION

Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents

(2009) Shinya Shibutani et al.   INTERNATIONAL JOURNAL OF CANCER

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells

(2009) Sivaprasad Attaluri et al.   NUCLEIC ACIDS RESEARCH

Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity

(2008) Y. Xiao et al.   KIDNEY INTERNATIONAL