Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy

(2013) M. Refik Gökmen et al.   ANNALS OF INTERNAL MEDICINE

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: Clinical characteristics and outcomes

(2013) Chung-Hsin Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

(2013) M. L. Hoang et al.   Science Translational Medicine

Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

(2012) Jueng Soo You et al.   CANCER CELL

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Clinical and pathological spectrums of aristolochic acid nephropathy

(2012) Dongmei Chen et al.   CLINICAL NEPHROLOGY

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

(2012) Wing-Kin Sung et al.   NATURE GENETICS

Exome sequencing of liver fluke–associated cholangiocarcinoma

(2012) Choon Kiat Ong et al.   NATURE GENETICS

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

(2012) Zhi Jiang Zang et al.   NATURE GENETICS

TFIIH: when transcription met DNA repair

(2012) Emmanuel Compe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aristolochia Manshuriensis Kom Inhibits Adipocyte Differentiation by Regulation of ERK1/2 and Akt Pathway

(2012) Dong Hoon Kwak et al.   PLoS One

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole-genome reconstruction and mutational signatures in gastric cancer

(2012) Niranjan Nagarajan et al.   GENOME BIOLOGY

TP53 Mutational signature for aristolochic acid: an environmental carcinogen

(2011) Masaaki Moriya et al.   INTERNATIONAL JOURNAL OF CANCER

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

(2011) Bojan Jelaković et al.   KIDNEY INTERNATIONAL

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

(2011) Kai Wang et al.   NATURE GENETICS

Coding repeats coordinate repression

(2011) Mary Muers   NATURE REVIEWS GENETICS

Structure and stability of DNA containing an aristolactam II-dA lesion: implications for the NER recognition of bulky adducts

(2011) Mark Lukin et al.   NUCLEIC ACIDS RESEARCH

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

(2011) Victoria S. Sidorenko et al.   NUCLEIC ACIDS RESEARCH

Expression of parvin-β is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract

(2010) C-F Wu et al.   BRITISH JOURNAL OF CANCER

Identification of genetic alterations in upper urinary tract urothelial carcinoma in end-stage renal disease patients

(2010) Ching-Fang Wu et al.   GENES CHROMOSOMES & CANCER

Recognition of Damaged DNA: Structure and Dynamic Markers

(2010) Markus W. Germann et al.   MEDICINAL RESEARCH REVIEWS

Nonsense-Mediated RNA Decay Regulation by Cellular Stress: Implications for Tumorigenesis

(2010) L. B. Gardner   MOLECULAR CANCER RESEARCH

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

Biotransformation enzymes in development of renal injury and urothelial cancer caused by aristolochic acid

(2008) M. Stiborová et al.   KIDNEY INTERNATIONAL

Aristolochic acid nephropathy: A worldwide problem

(2008) Frédéric D. Debelle et al.   KIDNEY INTERNATIONAL