The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats

The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy

(2013) M. Refik Gökmen et al.   ANNALS OF INTERNAL MEDICINE

Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer

(2013) Marie Stiborova et al.   CURRENT DRUG METABOLISM

Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

(2013) S. L. Poon et al.   Science Translational Medicine

Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

(2013) M. L. Hoang et al.   Science Translational Medicine

Biomonitoring of Aristolactam-DNA Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry

(2012) Byeong Hwa Yun et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I

(2012) Katerina Levova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells

(2012) Shaohua Zhu et al.   TOXICOLOGY IN VITRO

Rosuvastatin suppresses the liver microsomal CYP2C11 and CYP2C6 expression in male Wistar rats

(2012) Alice Zachařová et al.   XENOBIOTICA

New Anticoagulants in Ischemic Heart Disease

(2012) Lawrence Rajan et al.   Current Cardiology Reports

Fenofibrate-induced decrease of expression of CYP2C11 and CYP2C6 in rat

(2011) Rostislav Večeřa et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Functional study of the vitamin K cycle in mammalian cells

(2011) J.-K. Tie et al.   BLOOD

Role of P450 1A1 and P450 1A2 in Bioactivation versus Detoxication of the Renal Carcinogen Aristolochic Acid I: Studies inCyp1a1(−/−),Cyp1a2(−/−), andCyp1a1/1a2(−/−)Mice

(2011) Volker M. Arlt et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases

(2011) Marie Stiborová et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

TP53 Mutational signature for aristolochic acid: an environmental carcinogen

(2011) Masaaki Moriya et al.   INTERNATIONAL JOURNAL OF CANCER

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

(2011) Bojan Jelaković et al.   KIDNEY INTERNATIONAL

Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model

(2011) Kateřina Levová et al.   TOXICOLOGICAL SCIENCES

Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2

(2011) Marie Stiborová et al.   TOXICOLOGICAL SCIENCES

Inhibition of Renal NQO1 Activity by Dicoumarol Suppresses Nitroreduction of Aristolochic Acid I and Attenuates its Nephrotoxicity

(2011) Min Chen et al.   TOXICOLOGICAL SCIENCES

Aristolochic acid I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells

(2011) Feng-Yih Yu et al.   TOXICOLOGY IN VITRO

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

(2011) Christopher R. Pudney et al.   PLOS BIOLOGY

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

(2010) Albena T. Dinkova-Kostova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450

(2010) Tomas Laursen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the Mouse

(2010) T. A. Rosenquist et al.   DRUG METABOLISM AND DISPOSITION

Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice

(2010) Volker M. Arlt et al.   INTERNATIONAL JOURNAL OF CANCER

Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents

(2009) Shinya Shibutani et al.   INTERNATIONAL JOURNAL OF CANCER

Aristolochic acid nephropathy: A worldwide problem

(2008) Frédéric D. Debelle et al.   KIDNEY INTERNATIONAL

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

(2007) Marie Stiborová et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH