Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: Clinical characteristics and outcomes

(2013) Chung-Hsin Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

(2013) S. L. Poon et al.   Science Translational Medicine

Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non–small cell lung carcinoma from Chinese patients

(2012) Donghai Xiong et al.   CARCINOGENESIS

Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing

(2012) Pengyuan Liu et al.   CARCINOGENESIS

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Biomonitoring of Aristolactam-DNA Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry

(2012) Byeong Hwa Yun et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy

(2012) Marc E. De Broe   KIDNEY INTERNATIONAL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

(2012) Charles M Rudin et al.   NATURE GENETICS

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

(2012) Michael Krauthammer et al.   NATURE GENETICS

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TP53 Mutational signature for aristolochic acid: an environmental carcinogen

(2011) Masaaki Moriya et al.   INTERNATIONAL JOURNAL OF CANCER

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

(2011) Bojan Jelaković et al.   KIDNEY INTERNATIONAL

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

(2011) Mitchell S Stark et al.   NATURE GENETICS

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

(2011) Xiaomu Wei et al.   NATURE GENETICS

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

(2011) Victoria S. Sidorenko et al.   NUCLEIC ACIDS RESEARCH

Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

(2011) C. Bettegowda et al.   SCIENCE

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

The mutation spectrum revealed by paired genome sequences from a lung cancer patient

(2010) William Lee et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk

(2009) M.-N. Lai et al.   JNCI-Journal of the National Cancer Institute

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells

(2009) Sivaprasad Attaluri et al.   NUCLEIC ACIDS RESEARCH

FGFR3 Mutations Indicate Better Survival in Invasive Upper Urinary Tract and Bladder Tumours

(2008) Johanna M.M. van Oers et al.   EUROPEAN UROLOGY

TP53mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

(2008) Tatiana Nedelko et al.   INTERNATIONAL JOURNAL OF CANCER

Prescription profile of potentially aristolochic acid containing Chinese herbal products: an analysis of National Health Insurance data in Taiwan between 1997 and 2003

(2008) Shu-Ching Hsieh et al.   Chinese Medicine